Murielle Bochud

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Murielle Bochud is assistant professor of epidemiology at the University Institute of Social and Preventive Medicine in Lausanne. She has a Swiss federal diploma of Medicine from Geneva University (1994), an MD from Lausanne University (2002) and a PhD in genetic epidemiology from Case Western Reserve University (2007). Her research focuses on the epidemiology of blood pressure and related cardiovascular traits, including their genetic determinants.


Contact

Unité de Prévention Communautaire

Institut Universitaire de Médecine Sociale et Préventive

Rue du Bugnon 17

1005 Lausanne

Phone: ++41 21 314 08 99

E-mail: Murielle.Bochud@chuv.ch


Epidemiology of alcohol consumption

For a general review see [1].

When moderate, alcohol consumption is associated with beneficial health outcomes, such as decreased all-cause and cardiovascular mortality [1, 2]. By contrast, excess alcohol consumption is associated with increased all-cause mortality [2]. There is a j-shape relationship between alcohol consumption and mortality[2]. Among the negative health outcomes associated with elevated alcohol consumption are type 2 diabetes, neuropsychiatric conditions, cardiovascular diseases, digestive diseases as well as intentional and unintential injuries.

Fewer women than men consume alcohol and women who drink alcohol consume less than men [3].

The principal sources of dietary ethanol are beer, distilled spirits, and wine [3]. Ethanol (C2H5OH) is a physiologically nonessential molecule that is metabolized mainly in the liver.


References and selected course readings

  1. Lindberg ML and Amsterdam EA. Alcohol, wine, and cardiovascular health. Clin Cardiol 2008 Aug; 31(8) 347-51. doi:10.1002/clc.20263 pmid:18727003. PubMed HubMed [1]
  2. Di Castelnuovo A, Costanzo S, Bagnardi V, Donati MB, Iacoviello L, and de Gaetano G. Alcohol dosing and total mortality in men and women: an updated meta-analysis of 34 prospective studies. Arch Intern Med 2006 Dec 11-25; 166(22) 2437-45. doi:10.1001/archinte.166.22.2437 pmid:17159008. PubMed HubMed [2]
  3. Ferreira MP and Weems MK. Alcohol consumption by aging adults in the United States: health benefits and detriments. J Am Diet Assoc 2008 Oct; 108(10) 1668-76. doi:10.1016/j.jada.2008.07.011 pmid:18926132. PubMed HubMed [3]
All Medline abstracts: PubMed HubMed