User:PedroMarquesVidal

Contact

Pedro Marques-Vidal

Chef de Clinique Adjoint

Institut Universitaire de Médecine Sociale et Préventive

17, rue du Bugnon

1005 Lausanne

Phone: +41 21 314 72 65

Fax: +41 21 314 73 73

Email: Pedro-Manuel.Marques-Vidal@chuv.ch

Topic

Goal: The goal of the project is to perform a genome-wide association study that will potentially identify SNPs that are related to cardiovascular risk and compare the results between genders

Mathematical tools: The tool of choice for this project is logistic regression analysis. The student will learn the basics of regressing a given phenotype to a genotype and how this analysis is implemented on a computer to handle a large number of SNPs.

References

Silander K, Alanne M, Kristiansson K, Saarela O, Ripatti S, et al. (2008) Gender Differences in Genetic Risk Profiles for Cardiovascular Disease. PLoS ONE 3(10): e3615. doi:10.1371/journal.pone.0003615