WingX: Systems Biology of the Drosophila Wing

From Computational Biology Group

Jump to: navigation, search

Some people of our group are part of the Swiss WingX project. The goal of this project is to generate quantitative datasets that serve as input for multi-scale modeling approaches of wing development and morphogenesis. These models will make experimentally testable predictions on the biophysical properties and molecular regulatory circuits that control the basic size and shape of the wing. In our group, we will investigate among other things how (and how much!) robustness is achieved during wing imaginal disc patterning.

Introductory reading

  • Introduction to Systems Biology, Uri Alon
  • Developmental Biology, Gilbert

Recommended reading


  • Review on morphogens [1]
  • Review on Dpp gradient formation [2]
  • Dpp gradient formation with facilitated (restricted) external diffusion [3]
  • Wingless gradient formation [4] (see [5] for modeling)

Growth and size regulation

  • From the tissue perspective [6]


Error fetching PMID 14757636:
Error fetching PMID 17703237:
Error fetching PMID 15479640:
Error fetching PMID 17074313:
Error fetching PMID 10744972:
Error fetching PMID 17293093:
  1. Error fetching PMID 14757636: [tabata]
  2. Error fetching PMID 17703237: [affbasler]
  3. Error fetching PMID 15479640: [belenkaya]
  4. Error fetching PMID 10744972: [striginicohen]
  5. Error fetching PMID 17074313: [hufnagel]
  6. Error fetching PMID 17293093: [aegerter]
All Medline abstracts: PubMed HubMed