Under-expression is coded with green,
over-expression with red color.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
nucleic acid binding
Interacting selectively with any nucleic acid.
DNA binding
Interacting selectively with DNA (deoxyribonucleic acid).
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
monooxygenase activity
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
binding
The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.
all
This term is the most general term possible
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 00830 | 6.613e-03 | 0.2344 | 4 | 21 | Retinol metabolism |
| 00982 | 3.458e-02 | 0.4018 | 4 | 36 | Drug metabolism - cytochrome P450 |
| 00980 | 3.740e-02 | 0.4129 | 4 | 37 | Metabolism of xenobiotics by cytochrome P450 |
ABCG1ATP-binding cassette, sub-family G (WHITE), member 1 (204567_s_at), score: -0.72 ACOT11acyl-CoA thioesterase 11 (216103_at), score: -0.82 ADORA2Aadenosine A2a receptor (205013_s_at), score: -0.79 ALDOAP2aldolase A, fructose-bisphosphate pseudogene 2 (211617_at), score: -0.81 ALMS1Alstrom syndrome 1 (214707_x_at), score: -0.92 ANKRD10ankyrin repeat domain 10 (218093_s_at), score: -0.59 APBB2amyloid beta (A4) precursor protein-binding, family B, member 2 (212972_x_at), score: -0.86 ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (216954_x_at), score: -0.61 BCL9B-cell CLL/lymphoma 9 (204129_at), score: -0.77 BTF3L2basic transcription factor 3, like 2 (217461_x_at), score: -0.59 C11orf57chromosome 11 open reading frame 57 (218314_s_at), score: -0.6 C17orf86chromosome 17 open reading frame 86 (221621_at), score: -0.86 CADM4cell adhesion molecule 4 (222293_at), score: -0.59 CBFA2T2core-binding factor, runt domain, alpha subunit 2; translocated to, 2 (207625_s_at), score: -0.79 CDC14ACDC14 cell division cycle 14 homolog A (S. cerevisiae) (205288_at), score: -0.74 CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2) (213183_s_at), score: -0.9 CEP27centrosomal protein 27kDa (220071_x_at), score: -0.73 CGGBP1CGG triplet repeat binding protein 1 (214050_at), score: -0.76 CHI3L1chitinase 3-like 1 (cartilage glycoprotein-39) (209395_at), score: -0.76 CIRBPcold inducible RNA binding protein (200811_at), score: -0.73 CISD3CDGSH iron sulfur domain 3 (213551_x_at), score: -0.71 CLEC4EC-type lectin domain family 4, member E (219859_at), score: -0.61 CNOT6CCR4-NOT transcription complex, subunit 6 (217970_s_at), score: -0.62 CPEcarboxypeptidase E (201117_s_at), score: -0.69 CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2 (207608_x_at), score: -0.64 CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 6 (217133_x_at), score: -0.76 CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4 (205998_x_at), score: -0.6 DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides (219290_x_at), score: -0.97 DAZ1deleted in azoospermia 1 (216922_x_at), score: -0.69 DAZ3deleted in azoospermia 3 (208281_x_at), score: -0.65 DAZ4deleted in azoospermia 4 (216351_x_at), score: -0.78 DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila) (215529_x_at), score: -0.7 DKFZp686O1327hypothetical gene supported by BC043549; BX648102 (216877_at), score: -0.77 DNAH3dynein, axonemal, heavy chain 3 (220725_x_at), score: -0.9 ELK4ELK4, ETS-domain protein (SRF accessory protein 1) (206919_at), score: -0.73 EPB41L1erythrocyte membrane protein band 4.1-like 1 (212339_at), score: -0.86 FAM106Afamily with sequence similarity 106, member A (220575_at), score: -0.64 FAM134Afamily with sequence similarity 134, member A (222129_at), score: -0.77 FAM53Bfamily with sequence similarity 53, member B (203206_at), score: -0.62 FBXL11F-box and leucine-rich repeat protein 11 (208989_s_at), score: -0.66 FBXO41F-box protein 41 (44040_at), score: -0.81 FBXW12F-box and WD repeat domain containing 12 (215600_x_at), score: -0.75 FCARFc fragment of IgA, receptor for (211305_x_at), score: -0.78 FGD6FYVE, RhoGEF and PH domain containing 6 (219901_at), score: -0.68 FKSG49FKSG49 (211454_x_at), score: -0.63 FLJ11292hypothetical protein FLJ11292 (220828_s_at), score: -0.94 FLJ21369hypothetical protein FLJ21369 (220401_at), score: -0.68 FLJ23172hypothetical LOC389177 (217016_x_at), score: -0.8 FNBP4formin binding protein 4 (212232_at), score: -0.67 G3BP1GTPase activating protein (SH3 domain) binding protein 1 (222187_x_at), score: -0.98 GCLCglutamate-cysteine ligase, catalytic subunit (202922_at), score: -0.65 GTPBP3GTP binding protein 3 (mitochondrial) (213835_x_at), score: -0.65 HCG2P7HLA complex group 2 pseudogene 7 (216229_x_at), score: -0.85 HEY1hairy/enhancer-of-split related with YRPW motif 1 (44783_s_at), score: -0.79 HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) (213359_at), score: -0.74 IBD12Inflammatory bowel disease 12 (215373_x_at), score: -0.89 IMAASLC7A5 pseudogene (208118_x_at), score: -0.64 INSRinsulin receptor (213792_s_at), score: -0.63 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: -0.71 KCNJ14potassium inwardly-rectifying channel, subfamily J, member 14 (220776_at), score: -0.65 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: -0.6 KIAA0894KIAA0894 protein (207436_x_at), score: -0.61 KLF11Kruppel-like factor 11 (218486_at), score: -0.64 LAMB4laminin, beta 4 (215516_at), score: -0.63 LOC100128701heterogeneous nuclear ribonucleoprotein A1-like 2 pseudogene (216497_at), score: -0.64 LOC100128836similar to heterogeneous nuclear ribonucleoprotein A1 (217353_at), score: -0.61 LOC100129624hypothetical LOC100129624 (210748_at), score: -0.69 LOC100134401hypothetical protein LOC100134401 (213605_s_at), score: -0.75 LOC152719hypothetical protein LOC152719 (215978_x_at), score: -0.6 LOC23117PI-3-kinase-related kinase SMG-1 isoform 1 homolog (211996_s_at), score: -0.61 LOC51152melanoma antigen (220771_at), score: -0.67 LOC643313similar to hypothetical protein LOC284701 (211050_x_at), score: -0.75 LOC647070hypothetical LOC647070 (215467_x_at), score: -0.78 LOC728844hypothetical LOC728844 (222040_at), score: -0.63 LOC91316glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene (215816_at), score: -0.61 LRP4low density lipoprotein receptor-related protein 4 (212850_s_at), score: -0.71 MAP2K7mitogen-activated protein kinase kinase 7 (216206_x_at), score: -0.83 MAP3K9mitogen-activated protein kinase kinase kinase 9 (213927_at), score: -0.67 MCL1myeloid cell leukemia sequence 1 (BCL2-related) (214057_at), score: -0.62 MEFVMediterranean fever (208262_x_at), score: -0.82 METAP2methionyl aminopeptidase 2 (202015_x_at), score: -0.84 METTL7Amethyltransferase like 7A (211424_x_at), score: -0.91 MFSD11major facilitator superfamily domain containing 11 (221192_x_at), score: -0.74 MLLT10myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (216506_x_at), score: -0.68 MOGmyelin oligodendrocyte glycoprotein (214650_x_at), score: -0.59 MRPL44mitochondrial ribosomal protein L44 (218202_x_at), score: -0.74 NACAnascent polypeptide-associated complex alpha subunit (222018_at), score: -0.67 NACA2nascent polypeptide-associated complex alpha subunit 2 (222224_at), score: -0.6 NCRNA00092non-protein coding RNA 92 (215861_at), score: -0.63 NPIPL2nuclear pore complex interacting protein-like 2 (221992_at), score: -0.61 OPHN1oligophrenin 1 (206323_x_at), score: -0.63 PCGF2polycomb group ring finger 2 (203793_x_at), score: -0.69 PDE4Cphosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila) (206792_x_at), score: -0.74 PELI2pellino homolog 2 (Drosophila) (219132_at), score: -0.66 PER2period homolog 2 (Drosophila) (205251_at), score: -0.69 PGFplacental growth factor (215179_x_at), score: -0.69 PMS2CLPMS2 C-terminal like pseudogene (221206_at), score: -0.67 POGZpogo transposable element with ZNF domain (215281_x_at), score: -0.86 POLR1Bpolymerase (RNA) I polypeptide B, 128kDa (220113_x_at), score: -0.75 POM121L9PPOM121 membrane glycoprotein-like 9 (rat) pseudogene (222253_s_at), score: -0.75 PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha (219195_at), score: -0.82 PRINSpsoriasis associated RNA induced by stress (non-protein coding) (216051_x_at), score: -0.89 RGS5regulator of G-protein signaling 5 (218353_at), score: -0.7 RHEBRas homolog enriched in brain (213409_s_at), score: -0.62 RNMTRNA (guanine-7-) methyltransferase (202683_s_at), score: -0.67 RP3-377H14.5hypothetical LOC285830 (222279_at), score: -0.62 RPL21P37ribosomal protein L21 pseudogene 37 (216479_at), score: -0.84 RPL23AP32ribosomal protein L23a pseudogene 32 (207283_at), score: -0.67 RPL35Aribosomal protein L35a (215208_x_at), score: -0.81 RPS10P3ribosomal protein S10 pseudogene 3 (217336_at), score: -0.62 SAP30LSAP30-like (219129_s_at), score: -0.65 SAPS2SAPS domain family, member 2 (202792_s_at), score: -0.68 SCARF1scavenger receptor class F, member 1 (206995_x_at), score: -0.74 SCD5stearoyl-CoA desaturase 5 (220232_at), score: -0.73 SCML2sex comb on midleg-like 2 (Drosophila) (206147_x_at), score: -0.67 SERF1Bsmall EDRK-rich factor 1B (centromeric) (219982_s_at), score: -0.71 SFRS11splicing factor, arginine/serine-rich 11 (213742_at), score: -0.68 SFTPBsurfactant protein B (214354_x_at), score: -0.73 SH3BP2SH3-domain binding protein 2 (217257_at), score: -0.86 SH3GL3SH3-domain GRB2-like 3 (211565_at), score: -0.88 SKP1S-phase kinase-associated protein 1 (200719_at), score: -0.76 SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (217473_x_at), score: -0.73 SLC30A5solute carrier family 30 (zinc transporter), member 5 (220181_x_at), score: -0.95 SLC35F2solute carrier family 35, member F2 (218826_at), score: -0.64 SLC6A6solute carrier family 6 (neurotransmitter transporter, taurine), member 6 (205921_s_at), score: -0.66 SPATA2spermatogenesis associated 2 (204433_s_at), score: -0.67 SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome) (215383_x_at), score: -0.65 SPINLW1serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin) (206318_at), score: -0.92 SPNsialophorin (206057_x_at), score: -0.87 SPTLC3serine palmitoyltransferase, long chain base subunit 3 (220456_at), score: -1 SYCP1synaptonemal complex protein 1 (206740_x_at), score: -0.64 TCTN2tectonic family member 2 (206438_x_at), score: -0.71 TIGD1Ltigger transposable element derived 1-like (216459_x_at), score: -0.59 TIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast) (210800_at), score: -0.93 TP53TG3TP53 target 3 (220167_s_at), score: -0.68 TRIM36tripartite motif-containing 36 (219736_at), score: -0.77 UBQLN4ubiquilin 4 (222252_x_at), score: -0.82 UGT2B28UDP glucuronosyltransferase 2 family, polypeptide B28 (211682_x_at), score: -0.68 VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) (201557_at), score: -0.97 VEZTvezatin, adherens junctions transmembrane protein (207263_x_at), score: -0.7 XRCC2X-ray repair complementing defective repair in Chinese hamster cells 2 (207598_x_at), score: -0.79 ZBTB39zinc finger and BTB domain containing 39 (205256_at), score: -0.81 ZC3H7Bzinc finger CCCH-type containing 7B (206169_x_at), score: -0.89 ZMIZ1zinc finger, MIZ-type containing 1 (212124_at), score: -0.59 ZNF117zinc finger protein 117 (207605_x_at), score: -0.6 ZNF160zinc finger protein 160 (214715_x_at), score: -0.68 ZNF440zinc finger protein 440 (215892_at), score: -0.7 ZNF451zinc finger protein 451 (212557_at), score: -0.59 ZNF492zinc finger protein 492 (215532_x_at), score: -0.78 ZNF528zinc finger protein 528 (215019_x_at), score: -0.67 ZNF552zinc finger protein 552 (219741_x_at), score: -0.65 ZNF611zinc finger protein 611 (208137_x_at), score: -0.62 ZNF639zinc finger protein 639 (218413_s_at), score: -0.79 ZNF701zinc finger protein 701 (220242_x_at), score: -0.6 ZNF816Azinc finger protein 816A (217541_x_at), score: -0.89 ZSCAN12zinc finger and SCAN domain containing 12 (206507_at), score: -0.72
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-4219-raw-cel-1311956083.cel | 2 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956634.cel | 19 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956398.cel | 12 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956275.cel | 8 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| E-TABM-263-raw-cel-1515485651.cel | 1 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-GEOD-4219-raw-cel-1311956178.cel | 6 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956358.cel | 10 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956824.cel | 24 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
