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DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

chromosome segregation

The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.

chromosome organization

A process that is carried out at the cellular level that results in the formation, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information.

mitotic sister chromatid segregation

The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

cell cycle checkpoint

The cell cycle regulatory process by which progression through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

mitotic cell cycle

Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.

M phase

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division.

nuclear division

A process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.

DNA synthesis during DNA repair

Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

cellular alcohol metabolic process

The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

DNA-dependent DNA replication

The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.

DNA replication initiation

The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.

DNA strand elongation during DNA replication

The process by which a DNA strand is synthesized from template DNA during replication by the action of polymerases, which add nucleotides to the 3' end of the nascent DNA strand.

DNA repair

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

nucleotide-excision repair

In nucleotide excision repair a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).

nucleotide-excision repair, DNA gap filling

Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.

DNA packaging

Any process by which DNA and associated proteins are formed into a compact, orderly structure.

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

cholesterol biosynthetic process

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.

cell motion

Any process involved in the controlled movement of a cell.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

response to DNA damage stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

organelle organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

microtubule-based process

Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

mitotic cell cycle checkpoint

A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.

regulation of mitotic cell cycle

Any process that modulates the rate or extent of progress through the mitotic cell cycle.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

cholesterol metabolic process

The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

biosynthetic process

The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell cycle process

Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cellular component organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component.

sterol metabolic process

The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

sterol biosynthetic process

The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

cell migration

The orderly movement of cells from one site to another, often during the development of a multicellular organism or multicellular structure.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cell cycle phase

A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.

DNA strand elongation

The DNA metabolic process by which a DNA strand is synthesized by adding nucleotides to the 3' end of an existing DNA stand.

chromosome condensation

The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.

cellular response to stress

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

cellular response to DNA damage stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

locomotion

Self-propelled movement of a cell or organism from one location to another.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.

biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

organelle fission

The creation of two or more organelles by division of one organelle.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

cell division

The process resulting in the physical partitioning and separation of a cell into daughter cells.

S phase

A cell cycle process comprising the steps by which a cell progresses through S phase, the part of the cell cycle during which DNA synthesis takes place.

interphase

A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of chromosome segregation. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.

interphase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.

localization of cell

Any process by which a cell is transported to, and/or maintained in, a specific location.

cellular response to stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cellular response to stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cellular response to stress

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

cell motion

Any process involved in the controlled movement of a cell.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

regulation of mitotic cell cycle

Any process that modulates the rate or extent of progress through the mitotic cell cycle.

regulation of cell cycle process

Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

cellular response to DNA damage stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

sterol metabolic process

The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

sterol biosynthetic process

The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

mitotic cell cycle checkpoint

A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

chromosome condensation

The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

mitotic sister chromatid segregation

The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

S phase

A cell cycle process comprising the steps by which a cell progresses through S phase, the part of the cell cycle during which DNA synthesis takes place.

interphase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.

DNA repair

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

cholesterol biosynthetic process

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.

DNA synthesis during DNA repair

Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

DNA replication initiation

The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.

DNA strand elongation during DNA replication

The process by which a DNA strand is synthesized from template DNA during replication by the action of polymerases, which add nucleotides to the 3' end of the nascent DNA strand.

nucleotide-excision repair, DNA gap filling

Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.

nuclear chromosome

A chromosome found in the nucleus of a eukaryotic cell.

condensed chromosome

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosome, centromeric region

The region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

outer kinetochore of condensed chromosome

The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

replication fork

The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

chromosome

A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

microtubule cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

membrane-enclosed lumen

The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.

nuclear lumen

The volume enclosed by the nuclear inner membrane.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

protein-DNA complex

A macromolecular complex containing both protein and DNA molecules.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

nuclear replication fork

The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

nuclear part

Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

intracellular organelle lumen

An organelle lumen that is part of an intracellular organelle.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular organelle lumen

An organelle lumen that is part of an intracellular organelle.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

outer kinetochore of condensed chromosome

The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

nuclear lumen

The volume enclosed by the nuclear inner membrane.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

outer kinetochore of condensed chromosome

The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.

nuclear part

Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.

nuclear chromosome

A chromosome found in the nucleus of a eukaryotic cell.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

nuclear replication fork

The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

nucleotide binding

Interacting selectively with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose moiety.

protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

motor activity

Catalysis of movement along a polymeric molecule such as a microfilament or microtubule, coupled to the hydrolysis of a nucleoside triphosphate.

microtubule motor activity

Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

DNA-directed DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.

nucleoside-triphosphatase activity

Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

ATP binding

Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

pyrophosphatase activity

Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.

transferase activity

Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

nucleotidyltransferase activity

Catalysis of the transfer of a nucleotidyl group to a reactant.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

hydrolase activity, acting on acid anhydrides

Catalysis of the hydrolysis of any acid anhydride.

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.

purine nucleotide binding

Interacting selectively with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.

adenyl nucleotide binding

Interacting selectively with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate.

ribonucleotide binding

Interacting selectively with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.

purine ribonucleotide binding

Interacting selectively with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.

adenyl ribonucleotide binding

Interacting selectively with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.

DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and primer.

all

This term is the most general term possible

purine ribonucleotide binding

Interacting selectively with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.

adenyl ribonucleotide binding

Interacting selectively with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0022403	1.805e-22	9.743	53 ASPM, AURKB, BIRC5, BLM, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDC7, CDCA3, CDCA8, CDK2, CDT1, CENPE, CENPF, DDX11, DLGAP5, DSN1, ERCC6L, EXO1, GTSE1, IL1A, IL1B, KIF11, KIF15, KIF20B, KIF22, KIF2C, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, POLA1, POLD1, POLE, PSMC3IP, RAD54B, RAD54L, SMC2, SPC25, TACC3, TIMELESS, TPD52L1, TPX2, TTK	285	cell cycle phase
GO:0000279	1.377e-19	7.863	45 ASPM, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, DDX11, DLGAP5, DSN1, ERCC6L, EXO1, IL1A, IL1B, KIF11, KIF15, KIF20B, KIF22, KIF2C, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, PSMC3IP, RAD54B, RAD54L, SMC2, SPC25, TACC3, TIMELESS, TPX2, TTK	230	M phase
GO:0000280	5.549e-19	5.914	39 ASPM, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, DDX11, DLGAP5, DSN1, ERCC6L, IL1A, IL1B, KIF11, KIF15, KIF20B, KIF22, KIF2C, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, SMC2, SPC25, TIMELESS, TPX2	173	nuclear division
GO:0007067	5.549e-19	5.914	39 ASPM, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, DDX11, DLGAP5, DSN1, ERCC6L, IL1A, IL1B, KIF11, KIF15, KIF20B, KIF22, KIF2C, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, SMC2, SPC25, TIMELESS, TPX2	173	mitosis
GO:0000087	1.075e-18	6.017	39 ASPM, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, DDX11, DLGAP5, DSN1, ERCC6L, IL1A, IL1B, KIF11, KIF15, KIF20B, KIF22, KIF2C, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, SMC2, SPC25, TIMELESS, TPX2	176	M phase of mitotic cell cycle
GO:0048285	2.051e-18	6.119	39 ASPM, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, DDX11, DLGAP5, DSN1, ERCC6L, IL1A, IL1B, KIF11, KIF15, KIF20B, KIF22, KIF2C, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, SMC2, SPC25, TIMELESS, TPX2	179	organelle fission
GO:0007049	9.341e-18	22.08	72 ASPM, AURKB, BIRC5, BLM, BMP2, BUB1, BUB1B, C13orf15, C18orf24, C21orf45, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDCA3, CDCA8, CDK2, CDT1, CENPE, CENPF, CHAF1A, CHAF1B, CKAP2, DDX11, DLGAP5, DSN1, ERCC6L, EXO1, FANCG, GMNN, GTSE1, IL1A, IL1B, IL8, KIF11, KIF15, KIF20B, KIF22, KIF2C, LIG1, MAD2L1, MCM2, MCM3, MCM7, MKI67, MTSS1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, POLA1, POLD1, POLE, PSMC3IP, RAD54B, RAD54L, RBL1, RGS2, SMC2, SPC25, TACC3, TIMELESS, TP53BP2, TPD52L1, TPX2, TTK	646	cell cycle
GO:0022402	1.361e-16	13.4	54 ASPM, AURKB, BIRC5, BLM, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDC7, CDCA3, CDCA8, CDK2, CDT1, CENPE, CENPF, DDX11, DLGAP5, DSN1, ERCC6L, EXO1, GTSE1, IL1A, IL1B, IL8, KIF11, KIF15, KIF20B, KIF22, KIF2C, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, POLA1, POLD1, POLE, PSMC3IP, RAD54B, RAD54L, SMC2, SPC25, TACC3, TIMELESS, TPD52L1, TPX2, TTK	392	cell cycle process
GO:0000278	2.155e-16	10.7	48 ASPM, AURKB, BIRC5, BLM, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDC7, CDCA3, CDCA8, CDK2, CDT1, CENPE, CENPF, DDX11, DLGAP5, DSN1, ERCC6L, GTSE1, IL1A, IL1B, KIF11, KIF15, KIF20B, KIF22, KIF2C, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, POLA1, POLD1, POLE, SMC2, SPC25, TIMELESS, TPD52L1, TPX2, TTK	313	mitotic cell cycle
GO:0006260	1.204e-14	6.153	35 BLM, CDC45L, CDC6, CDC7, CDK2, CDT1, CHAF1A, CHAF1B, DTL, EXO1, GINS1, GINS2, GINS3, GMNN, HMGB2, LIG1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, ORC1L, ORC6L, PDGFA, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, RFC3, RFC4, RNASEH2A	180	DNA replication
GO:0051301	4.176e-12	6.564	33 ASPM, AURKB, BLM, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNE2, CDC20, CDC6, CDC7, CDCA3, CDCA8, CDK2, CENPE, CENPF, DSN1, ERCC6L, KIF11, KIF20B, LIG1, MAD2L1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, SMC2, SPC25, TIMELESS	192	cell division
GO:0006259	2.118e-08	12.68	40 BLM, CDC45L, CDC6, CDC7, CDK2, CDT1, CHAF1A, CHAF1B, DNASE2, DTL, EXO1, FANCG, GINS1, GINS2, GINS3, GMNN, HMGB2, LIG1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, ORC1L, ORC6L, PDGFA, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PSMC3IP, RAD54B, RAD54L, RFC3, RFC4, RNASEH2A	371	DNA metabolic process
GO:0006261	4.614e-08	2.085	16 CDC45L, CDC6, CDT1, EXO1, HMGB2, MCM2, MCM3, MCM4, MCM5, MCM7, ORC1L, POLA1, POLE2, PRIM1, RFC3, RFC4	61	DNA-dependent DNA replication
GO:0008283	5.494e-08	19.11	50 BLM, BMP2, BMPR2, BUB1, BUB1B, CCL2, CDC6, CDC7, CDK2, CENPF, CREG1, DDX11, DHCR7, DLGAP5, FABP3, FGF1, FGF7, GINS1, GPNMB, HBEGF, IL1A, IL1B, IL6, IL8, INSIG1, JARID2, KIF15, KIF2C, LIF, MCM7, MKI67, NAMPT, PDGFA, PDGFD, PDGFRB, POLA1, PTHLH, SOX9, STIL, TACC3, TACSTD2, TGFBR1, TIMELESS, TNFSF4, TNS3, TPX2, TRIB1, TTK, VEGFA, WNT2	559	cell proliferation
GO:0006270	9.815e-08	0.6837	10 CDC45L, CDC6, CDT1, MCM2, MCM3, MCM4, MCM5, MCM7, ORC1L, POLA1	20	DNA replication initiation
GO:0007346	1.295e-06	2.974	17 BLM, BUB1, BUB1B, CCNA2, CDC6, CDK2, CDT1, CENPF, DLGAP5, GTSE1, IL1A, IL1B, KIF20B, MAD2L1, NUSAP1, PKMYT1, TTK	87	regulation of mitotic cell cycle
GO:0051726	3.126e-06	8.786	29 BLM, BMP2, BUB1, BUB1B, C13orf15, CCNA2, CCNE2, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, DLGAP5, FANCG, GMNN, GTSE1, IL1A, IL1B, KIF20B, MAD2L1, MTSS1, NUSAP1, PKMYT1, RBL1, TACC3, TIMELESS, TP53BP2, TTK	257	regulation of cell cycle
GO:0000075	4.614e-06	1.812	13 BLM, BUB1, BUB1B, CCNA2, CCNE2, CDC45L, CDC6, CDT1, CENPF, FANCG, GTSE1, MAD2L1, TTK	53	cell cycle checkpoint
GO:0000070	8.209e-06	0.7863	9 CENPE, DDX11, DLGAP5, NCAPD3, NCAPG, NCAPH, NDC80, NUSAP1, SMC2	23	mitotic sister chromatid segregation
GO:0000819	1.226e-05	0.8205	9 CENPE, DDX11, DLGAP5, NCAPD3, NCAPG, NCAPH, NDC80, NUSAP1, SMC2	24	sister chromatid segregation
GO:0006996	2.780e-05	30.56	60 ASF1B, ASPM, AURKB, BIRC5, BLM, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDCA3, CDCA8, CDK2, CDYL, CENPE, CENPF, CHAF1A, CHAF1B, DDX11, DLGAP5, DSN1, ERCC6L, EXOSC9, EZH2, FANCG, HMGB2, IL1A, IL1B, JMJD3, KIF11, KIF15, KIF20B, KIF22, KIF2C, KIF4A, MAD2L1, MCM2, MTSS1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NR3C1, NUSAP1, OIP5, PDGFA, PKMYT1, PRKG1, RAD54L, RBL1, SMC2, SPC25, TACC3, TIMELESS, TPX2, TTK, WNT2	894	organelle organization
GO:0016126	2.831e-05	1.162	10 C14orf1, CYP51A1, DHCR7, HMGCR, HMGCS1, IDI1, LSS, SC4MOL, SQLE, TM7SF2	34	sterol biosynthetic process
GO:0016125	4.156e-05	2.188	13 C14orf1, CYP51A1, DHCR7, HMGCR, HMGCS1, IDI1, INSIG1, LDLR, LSS, SC4MOL, SQLE, SREBF2, TM7SF2	64	sterol metabolic process
GO:0007059	6.219e-05	1.573	11 CENPE, CENPF, DDX11, DLGAP5, DSN1, NCAPD3, NCAPG, NCAPH, NDC80, NUSAP1, SMC2	46	chromosome segregation
GO:0042127	9.574e-05	12.85	33 BLM, BMP2, BMPR2, CCL2, CDC6, CDC7, CDK2, DDX11, DHCR7, FABP3, FGF1, FGF7, GPNMB, HBEGF, IL1A, IL1B, IL6, IL8, JARID2, LIF, NAMPT, PDGFA, PDGFRB, PTHLH, SOX9, TGFBR1, TIMELESS, TNFSF4, TNS3, TRIB1, TTK, VEGFA, WNT2	376	regulation of cell proliferation
GO:0051325	1.767e-04	2.496	13 BLM, CDC6, CDC7, CDK2, CDT1, CENPF, DDX11, GTSE1, POLA1, POLD1, POLE, TIMELESS, TPD52L1	73	interphase
GO:0006694	4.097e-04	1.914	11 C14orf1, CYP51A1, DHCR7, HMGCR, HMGCS1, IDI1, LSS, NR3C1, SC4MOL, SQLE, TM7SF2	56	steroid biosynthetic process
GO:0051329	6.066e-04	2.393	12 BLM, CDC6, CDC7, CDK2, CDT1, CENPF, DDX11, GTSE1, POLA1, POLD1, POLE, TPD52L1	70	interphase of mitotic cell cycle
GO:0007093	6.454e-04	0.9914	8 BLM, BUB1, BUB1B, CCNA2, CENPF, GTSE1, MAD2L1, TTK	29	mitotic cell cycle checkpoint
GO:0008284	8.499e-04	6.393	20 BLM, CCL2, CDC7, CDK2, DDX11, FGF1, FGF7, HBEGF, IL1B, IL6, LIF, NAMPT, PDGFA, PDGFRB, PTHLH, TGFBR1, TNFSF4, TNS3, TTK, VEGFA	187	positive regulation of cell proliferation
GO:0051320	9.286e-04	0.5128	6 CDC7, CDT1, DDX11, POLA1, POLD1, TIMELESS	15	S phase
GO:0006066	1.284e-03	6.598	20 ALDOC, C14orf1, CYP51A1, DHCR7, GALNAC4S-6ST, GCH1, GDPD5, GFPT2, HK2, HMGCR, HMGCS1, IDI1, INSIG1, LDLR, LSS, NR3C1, SC4MOL, SQLE, SREBF2, TM7SF2	193	cellular alcohol metabolic process
GO:0007017	1.708e-03	4.581	16 BUB1B, CENPE, GTSE1, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, NDC80, NUSAP1, TACC3, TTK, WNT2	134	microtubule-based process
GO:0006297	1.922e-03	0.5812	6 LIG1, POLD1, POLE, POLE2, RFC3, RFC4	17	nucleotide-excision repair, DNA gap filling
GO:0006695	2.000e-03	0.8546	7 CYP51A1, DHCR7, HMGCR, HMGCS1, IDI1, LSS, TM7SF2	25	cholesterol biosynthetic process
GO:0008203	2.229e-03	1.914	10 CYP51A1, DHCR7, HMGCR, HMGCS1, IDI1, INSIG1, LDLR, LSS, SREBF2, TM7SF2	56	cholesterol metabolic process
GO:0008202	2.919e-03	3.795	14 C14orf1, CYP51A1, DHCR7, HMGCR, HMGCS1, IDI1, INSIG1, LDLR, LSS, NR3C1, SC4MOL, SQLE, SREBF2, TM7SF2	111	steroid metabolic process
GO:0007076	3.627e-03	0.4102	5 NCAPD3, NCAPG, NCAPH, NUSAP1, SMC2	12	mitotic chromosome condensation
GO:0006323	4.257e-03	2.085	10 ASF1B, CHAF1A, CHAF1B, HMGB2, MCM2, NCAPD3, NCAPG, NCAPH, NUSAP1, SMC2	61	DNA packaging
GO:0006271	4.681e-03	0.1026	3 POLA1, RFC3, RFC4	3	DNA strand elongation during DNA replication
GO:0010564	5.437e-03	1.743	9 CDC7, CDT1, DLGAP5, IL1A, IL1B, KIF20B, NUSAP1, PKMYT1, TIMELESS	51	regulation of cell cycle process
GO:0016477	6.525e-03	5.777	17 CCL2, HBEGF, HMGCR, ICAM1, IL1B, IL6, IL8, PDGFA, PDGFRB, PRKG1, SRF, TGFBR1, TNS3, TRIB1, VCL, VEGFA, WNT2	169	cell migration
GO:0000731	8.526e-03	0.2735	4 POLA1, POLD1, POLE, RFC3	8	DNA synthesis during DNA repair
GO:0048870	9.244e-03	5.982	17 CCL2, HBEGF, HMGCR, ICAM1, IL1B, IL6, IL8, PDGFA, PDGFRB, PRKG1, SRF, TGFBR1, TNS3, TRIB1, VCL, VEGFA, WNT2	175	cell motility
GO:0030261	9.889e-03	0.5128	5 NCAPD3, NCAPG, NCAPH, NUSAP1, SMC2	15	chromosome condensation
GO:0022616	1.351e-02	0.1367	3 POLA1, RFC3, RFC4	4	DNA strand elongation
GO:0050000	1.351e-02	0.1367	3 CENPE, CENPF, DLGAP5	4	chromosome localization
GO:0051303	1.351e-02	0.1367	3 CENPE, CENPF, DLGAP5	4	establishment of chromosome localization
GO:0051276	1.378e-02	9.367	22 ASF1B, BLM, CDYL, CENPE, CENPF, CHAF1A, CHAF1B, DDX11, DLGAP5, EZH2, HMGB2, JMJD3, MCM2, NCAPD3, NCAPG, NCAPH, NDC80, NR3C1, NUSAP1, RAD54L, RBL1, SMC2	274	chromosome organization
GO:0007018	1.508e-02	2.051	9 CENPE, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A	60	microtubule-based movement
GO:0002237	1.634e-02	0.5812	5 GCH1, IL1B, IL6, THBD, TRIB1	17	response to molecule of bacterial origin
GO:0006974	1.818e-02	8.957	21 BLM, CCNA2, CHAF1A, CHAF1B, DTL, EXO1, FANCG, GTSE1, HMGB2, LIG1, MCM7, POLA1, POLD1, POLE, POLE2, POLQ, RAD54B, RAD54L, RFC3, RFC4, TIMELESS	262	response to DNA damage stimulus
GO:0031570	1.907e-02	0.923	6 BLM, CCNA2, CDC45L, CDC6, CDT1, GTSE1	27	DNA integrity checkpoint
GO:0016043	2.143e-02	54.59	78 ADIPOR2, ASF1B, ASPM, AURKB, BIRC5, BLM, BMP2, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CDC20, CDC6, CDCA3, CDCA8, CDK2, CDYL, CENPE, CENPF, CHAF1A, CHAF1B, COL14A1, DDX11, DLGAP5, DSN1, EGR2, ERCC6L, EXOSC9, EZH2, FANCG, GCH1, HMGB2, IL1A, IL1B, IL6, JMJD3, KIF11, KIF15, KIF20B, KIF22, KIF2C, KIF4A, KLF7, LDLR, MAD2L1, MCM2, MTSS1, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NR3C1, NUSAP1, OIP5, PDGFA, PKMYT1, PLSCR4, PRKG1, QPRT, RAD54L, RBL1, RHOQ, SMC2, SOX9, SPC25, SRF, TACC3, TGFBR1, TIMELESS, TNXB, TPX2, TTK, VCL, VEGFA, WISP1, WNT2	1597	cellular component organization
GO:0044249	2.381e-02	78.52	104 ASF1B, ATF3, B3GNT2, BHLHE40, BLM, BMP2, BMPR2, C14orf1, CCNA2, CDC45L, CDC6, CDC7, CDK2, CDT1, CDYL, CENPF, CHAF1A, CHAF1B, CREG1, CYP51A1, DHCR7, DMD, DTL, DVL3, EGR2, EXO1, EZH2, FABP3, FOSB, FRY, GALNAC4S-6ST, GCH1, GINS1, GINS2, GINS3, GMNN, HIVEP1, HIVEP2, HLX, HMGB2, HMGCR, HMGCS1, IDI1, IL1A, IL1B, IL6, INSIG1, JARID2, JMJD3, KLF7, LDLR, LIF, LIG1, LMCD1, LSS, MAN1C1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, NAMPT, NFATC1, NFIL3, NFKB1, NR3C1, NR4A1, NR4A2, NR4A3, ORC1L, ORC6L, PDGFA, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PTHLH, QPRT, RAD54B, RBL1, REL, RELB, RFC3, RFC4, RNASEH2A, RUNX1, SC4MOL, SCD, SKIL, SOX9, SQLE, SREBF2, SRF, ST3GAL1, TGFBR1, TIMELESS, TM7SF2, TRIB1, TRIP13, VDR	2297	cellular biosynthetic process
GO:0006275	2.514e-02	1.367	7 BLM, CDC45L, CDC6, CDK2, CDT1, GMNN, PDGFA	40	regulation of DNA replication
GO:0006268	2.553e-02	0.376	4 HMGB2, MCM2, MCM4, MCM7	11	DNA unwinding during replication
GO:0000085	2.609e-02	0.1709	3 BLM, CENPF, GTSE1	5	G2 phase of mitotic cell cycle
GO:0007094	2.609e-02	0.1709	3 BUB1, CENPF, TTK	5	mitotic cell cycle spindle assembly checkpoint
GO:0031577	2.609e-02	0.1709	3 BUB1, CENPF, TTK	5	spindle checkpoint
GO:0048286	2.609e-02	0.1709	3 BMPR2, PTHLH, TNS3	5	alveolus development
GO:0051319	2.609e-02	0.1709	3 BLM, CENPF, GTSE1	5	G2 phase
GO:0009058	2.733e-02	79.82	105 ASF1B, ATF3, B3GNT2, BHLHE40, BLM, BMP2, BMPR2, C14orf1, CCNA2, CDC45L, CDC6, CDC7, CDK2, CDT1, CDYL, CENPF, CHAF1A, CHAF1B, CREG1, CYP51A1, DHCR7, DMD, DTL, DVL3, EGR2, EXO1, EZH2, FABP3, FOSB, FRY, GALNAC4S-6ST, GCH1, GFPT2, GINS1, GINS2, GINS3, GMNN, HIVEP1, HIVEP2, HLX, HMGB2, HMGCR, HMGCS1, IDI1, IL1A, IL1B, IL6, INSIG1, JARID2, JMJD3, KLF7, LDLR, LIF, LIG1, LMCD1, LSS, MAN1C1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, NAMPT, NFATC1, NFIL3, NFKB1, NR3C1, NR4A1, NR4A2, NR4A3, ORC1L, ORC6L, PDGFA, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PTHLH, QPRT, RAD54B, RBL1, REL, RELB, RFC3, RFC4, RNASEH2A, RUNX1, SC4MOL, SCD, SKIL, SOX9, SQLE, SREBF2, SRF, ST3GAL1, TGFBR1, TIMELESS, TM7SF2, TRIB1, TRIP13, VDR	2335	biosynthetic process
GO:0050900	2.968e-02	1.026	6 CCL2, ICAM1, IL1B, IL6, IL8, VEGFA	30	leukocyte migration
GO:0001932	3.214e-02	1.88	8 BMP2, IL1B, IL6, LIF, PDGFD, PDGFRB, TGFBR1, TTK	55	regulation of protein amino acid phosphorylation
GO:0000084	3.334e-02	0.4102	4 CDT1, DDX11, POLA1, POLD1	12	S phase of mitotic cell cycle
GO:0051272	3.461e-02	1.47	7 HBEGF, ICAM1, IL6, PDGFA, PDGFRB, TGFBR1, VEGFA	43	positive regulation of cell motion
GO:0030705	3.537e-02	2.393	9 CENPE, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A	70	cytoskeleton-dependent intracellular transport
GO:0040011	3.721e-02	7.658	18 CCL2, CXCL3, HBEGF, HMGCR, ICAM1, IL1B, IL6, IL8, PDGFA, PDGFRB, PRKG1, SRF, TGFBR1, TNS3, TRIB1, VCL, VEGFA, WNT2	224	locomotion
GO:0006928	4.015e-02	9.059	20 CCL2, EGR2, HBEGF, HMGCR, ICAM1, IL1B, IL6, IL8, KLF7, MTSS1, PDGFA, PDGFRB, PRKG1, SRF, TGFBR1, TNS3, TRIB1, VCL, VEGFA, WNT2	265	cell motion
GO:0051674	4.015e-02	9.059	20 CCL2, EGR2, HBEGF, HMGCR, ICAM1, IL1B, IL6, IL8, KLF7, MTSS1, PDGFA, PDGFRB, PRKG1, SRF, TGFBR1, TNS3, TRIB1, VCL, VEGFA, WNT2	265	localization of cell
GO:0000076	4.115e-02	0.2051	3 CDC45L, CDC6, CDT1	6	DNA replication checkpoint
GO:0010573	4.115e-02	0.2051	3 IL1A, IL1B, IL6	6	vascular endothelial growth factor production
GO:0010574	4.115e-02	0.2051	3 IL1A, IL1B, IL6	6	regulation of vascular endothelial growth factor production
GO:0032297	4.115e-02	0.2051	3 CDC45L, CDC6, CDT1	6	negative regulation of DNA replication initiation
GO:0048008	4.115e-02	0.2051	3 PDGFA, PDGFRB, VEGFA	6	platelet-derived growth factor receptor signaling pathway
GO:0008156	4.119e-02	0.7521	5 BLM, CDC45L, CDC6, CDT1, GMNN	22	negative regulation of DNA replication
GO:0045840	4.177e-02	0.4444	4 DLGAP5, IL1A, IL1B, NUSAP1	13	positive regulation of mitosis
GO:0001934	4.735e-02	1.162	6 BMP2, IL1B, IL6, LIF, TGFBR1, TTK	34	positive regulation of protein amino acid phosphorylation

Id	Pvalue	ExpCount	Count	Size	Term
GO:0044427	1.080e-14	6.664	36 ASF1B, AURKB, BLM, BUB1, BUB1B, C18orf24, C21orf45, CDCA8, CDT1, CDYL, CENPE, CENPF, CENPM, DSN1, ERCC6L, KIF22, KIF2C, MAD2L1, MCM2, MCM3, MCM7, NCAPD3, NCAPG, NCAPH, NDC80, OIP5, ORC6L, POLA1, POLA2, PRIM1, RANGAP1, RFC3, RFC4, SMC2, SPC25, TIMELESS	198	chromosomal part
GO:0005694	3.842e-13	8.347	38 ASF1B, AURKB, BIRC5, BLM, BUB1, BUB1B, C18orf24, C21orf45, CDCA8, CDT1, CDYL, CENPE, CENPF, CENPM, DSN1, ERCC6L, HMGB2, KIF22, KIF2C, MAD2L1, MCM2, MCM3, MCM7, NCAPD3, NCAPG, NCAPH, NDC80, OIP5, ORC6L, POLA1, POLA2, PRIM1, RANGAP1, RFC3, RFC4, SMC2, SPC25, TIMELESS	248	chromosome
GO:0000775	1.929e-10	2.12	18 AURKB, BUB1, BUB1B, C18orf24, C21orf45, CDCA8, CENPE, CENPF, CENPM, DSN1, ERCC6L, KIF22, KIF2C, MAD2L1, NDC80, OIP5, RANGAP1, SPC25	63	chromosome, centromeric region
GO:0000793	4.350e-09	2.221	17 BLM, BUB1, BUB1B, C18orf24, CENPE, CENPF, CENPM, DSN1, ERCC6L, HMGB2, NCAPD3, NCAPG, NCAPH, NDC80, RANGAP1, SMC2, SPC25	66	condensed chromosome
GO:0000776	2.175e-07	1.548	13 BUB1, BUB1B, C18orf24, CENPE, CENPF, CENPM, DSN1, ERCC6L, KIF22, MAD2L1, NDC80, RANGAP1, SPC25	46	kinetochore
GO:0005819	6.730e-07	2.693	16 AURKB, BUB1, BUB1B, C18orf24, CDC20, CDC6, CENPE, CENPF, DLGAP5, KIF11, KIF14, KIF15, KIF4A, NEDD9, TPX2, TTK	80	spindle
GO:0000777	7.265e-07	1.144	11 BUB1, BUB1B, C18orf24, CENPE, CENPF, CENPM, DSN1, ERCC6L, NDC80, RANGAP1, SPC25	34	condensed chromosome kinetochore
GO:0000779	7.265e-07	1.144	11 BUB1, BUB1B, C18orf24, CENPE, CENPF, CENPM, DSN1, ERCC6L, NDC80, RANGAP1, SPC25	34	condensed chromosome, centromeric region
GO:0043228	4.152e-06	45.07	80 ALDOC, ANGPTL4, ANK2, ASF1B, ATF3, AURKB, BIRC5, BLM, BUB1, BUB1B, C13orf15, C18orf24, C21orf45, CASP1, CDC20, CDC45L, CDC6, CDCA8, CDT1, CDYL, CENPE, CENPF, CENPM, CKAP2, CTSO, DDX11, DLGAP5, DMD, DSN1, ERCC6L, EXOSC9, GABARAPL1, GABARAPL3, GTSE1, HLX, HMGB2, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LMNB1, MAD2L1, MCM2, MCM3, MCM4, MCM7, MKI67, MTSS1, NCAPD3, NCAPG, NCAPH, NDC80, NDRG1, NEDD9, NR3C1, NUSAP1, OIP5, ORC6L, POLA1, POLA2, PPL, PRIM1, PRKG1, RANGAP1, RFC3, RFC4, SMC2, SOX9, SPC25, SRF, TIMELESS, TNS3, TPX2, TTK, VCL, WDHD1	1339	non-membrane-bounded organelle
GO:0043232	4.152e-06	45.07	80 ALDOC, ANGPTL4, ANK2, ASF1B, ATF3, AURKB, BIRC5, BLM, BUB1, BUB1B, C13orf15, C18orf24, C21orf45, CASP1, CDC20, CDC45L, CDC6, CDCA8, CDT1, CDYL, CENPE, CENPF, CENPM, CKAP2, CTSO, DDX11, DLGAP5, DMD, DSN1, ERCC6L, EXOSC9, GABARAPL1, GABARAPL3, GTSE1, HLX, HMGB2, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LMNB1, MAD2L1, MCM2, MCM3, MCM4, MCM7, MKI67, MTSS1, NCAPD3, NCAPG, NCAPH, NDC80, NDRG1, NEDD9, NR3C1, NUSAP1, OIP5, ORC6L, POLA1, POLA2, PPL, PRIM1, PRKG1, RANGAP1, RFC3, RFC4, SMC2, SOX9, SPC25, SRF, TIMELESS, TNS3, TPX2, TTK, VCL, WDHD1	1339	intracellular non-membrane-bounded organelle
GO:0005657	7.279e-06	0.8751	9 BLM, CDT1, MCM3, MCM7, POLA1, POLA2, PRIM1, RFC3, RFC4	26	replication fork
GO:0031981	8.698e-05	28.88	55 ANGPTL4, ATF3, BIRC5, BLM, CASP1, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, DDX11, EXOSC9, EZH2, GMNN, HLX, HMGB2, KIF20B, KIF4A, LIG1, LMNB1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MKI67, NFKB1, NR3C1, NR4A1, OIP5, ORC1L, ORC6L, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PRKG1, RBL1, RFC3, RFC4, SOX9, SRF, TNS3, WDHD1	858	nuclear lumen
GO:0000228	8.933e-05	2.592	13 BLM, BUB1, HMGB2, MCM2, MCM3, MCM7, NCAPD3, ORC6L, POLA1, POLA2, PRIM1, SMC2, TIMELESS	77	nuclear chromosome
GO:0044454	1.415e-04	1.918	11 BLM, BUB1, MCM2, MCM3, MCM7, NCAPD3, ORC6L, POLA1, POLA2, PRIM1, TIMELESS	57	nuclear chromosome part
GO:0005658	3.307e-04	0.1683	4 MCM3, POLA1, POLA2, PRIM1	5	alpha DNA polymerase:primase complex
GO:0044421	4.347e-04	12.66	30 ADAMTS5, ANGPTL4, ASPN, BMP2, CCL2, COL14A1, COL15A1, COL21A1, CXCL3, DKK2, ECM2, FGF1, HBEGF, ICAM1, IL1A, IL1B, IL6, IL8, LIF, MFAP4, OLFML2A, OMD, PDGFA, PRELP, PTHLH, THBD, TNFSF4, TNXB, VEGFA, WNT2	376	extracellular region part
GO:0015630	4.812e-04	10.8	27 AURKB, BUB1, BUB1B, C13orf15, C18orf24, CDC20, CDC45L, CDC6, CENPE, CENPF, CKAP2, DLGAP5, GABARAPL1, GABARAPL3, GTSE1, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, NEDD9, NUSAP1, TPX2, TTK	321	microtubule cytoskeleton
GO:0043596	7.843e-04	0.3702	5 MCM3, MCM7, POLA1, POLA2, PRIM1	11	nuclear replication fork
GO:0000796	8.491e-04	0.2019	4 NCAPD3, NCAPG, NCAPH, SMC2	6	condensin complex
GO:0044428	8.954e-04	37.86	63 ANGPTL4, ATF3, BIRC5, BLM, BUB1, BUB1B, CASP1, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, DDX11, DHCR7, DTL, EXOSC9, EZH2, GMNN, HLX, HMGB2, KIF20B, KIF4A, LIG1, LMNB1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MKI67, NCAPD3, NFKB1, NR3C1, NR4A1, OIP5, ORC1L, ORC6L, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PRKG1, RANGAP1, RBL1, RFC3, RFC4, SMC2, SOX9, SRF, TIMELESS, TNS3, WDHD1	1125	nuclear part
GO:0005654	1.218e-03	19.02	38 BLM, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDK2, CDT1, CHAF1A, CHAF1B, EZH2, GMNN, KIF20B, LIG1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, NFKB1, NR4A1, OIP5, ORC1L, ORC6L, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, RBL1, RFC3, RFC4, WDHD1	565	nucleoplasm
GO:0000940	1.624e-03	0.101	3 BUB1B, CENPE, CENPF	3	outer kinetochore of condensed chromosome
GO:0030894	5.012e-03	0.3029	4 MCM3, POLA1, POLA2, PRIM1	9	replisome
GO:0043601	5.012e-03	0.3029	4 MCM3, POLA1, POLA2, PRIM1	9	nuclear replisome
GO:0044446	6.496e-03	90.1	118 ABCA5, ANGPTL4, ASF1B, ATF3, AURKB, B3GNT2, BIRC5, BLM, BUB1, BUB1B, C13orf15, C14orf1, C18orf24, C21orf45, C4orf18, CASP1, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDCA8, CDK2, CDT1, CDYL, CENPE, CENPF, CENPM, CHAF1A, CHAF1B, CKAP2, CYP51A1, DDX11, DHCR7, DLGAP5, DRAM, DSN1, DTL, ENTPD7, ERCC6L, EXOSC9, EZH2, GABARAPL1, GABARAPL3, GALNAC4S-6ST, GMNN, GPR37, GTSE1, HK2, HLX, HMGB2, HMGCR, INSIG1, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LDLR, LIG1, LMNB1, MAD2L1, MAN1C1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MKI67, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NFKB1, NR3C1, NR4A1, NUSAP1, OIP5, ORC1L, ORC6L, PDGFA, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PRKG1, RANGAP1, RASGRP1, RBL1, RFC3, RFC4, SC4MOL, SCD, SMC2, SOX9, SPC25, SQLE, SREBF2, SRF, ST3GAL1, TIMELESS, TM7SF2, TNS3, TPX2, TTK, VEGFA, WDHD1, WNT2	2677	intracellular organelle part
GO:0043233	6.956e-03	35.95	57 ANGPTL4, ATF3, BIRC5, BLM, CASP1, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, DDX11, EXOSC9, EZH2, GMNN, HLX, HMGB2, KIF20B, KIF4A, LIG1, LMNB1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MKI67, NFKB1, NR3C1, NR4A1, OIP5, ORC1L, ORC6L, PDGFA, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PRKG1, RBL1, RFC3, RFC4, SOX9, SRF, TNS3, VEGFA, WDHD1	1068	organelle lumen
GO:0044422	7.530e-03	90.44	118 ABCA5, ANGPTL4, ASF1B, ATF3, AURKB, B3GNT2, BIRC5, BLM, BUB1, BUB1B, C13orf15, C14orf1, C18orf24, C21orf45, C4orf18, CASP1, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDCA8, CDK2, CDT1, CDYL, CENPE, CENPF, CENPM, CHAF1A, CHAF1B, CKAP2, CYP51A1, DDX11, DHCR7, DLGAP5, DRAM, DSN1, DTL, ENTPD7, ERCC6L, EXOSC9, EZH2, GABARAPL1, GABARAPL3, GALNAC4S-6ST, GMNN, GPR37, GTSE1, HK2, HLX, HMGB2, HMGCR, INSIG1, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LDLR, LIG1, LMNB1, MAD2L1, MAN1C1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MKI67, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NFKB1, NR3C1, NR4A1, NUSAP1, OIP5, ORC1L, ORC6L, PDGFA, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PRKG1, RANGAP1, RASGRP1, RBL1, RFC3, RFC4, SC4MOL, SCD, SMC2, SOX9, SPC25, SQLE, SREBF2, SRF, ST3GAL1, TIMELESS, TM7SF2, TNS3, TPX2, TTK, VEGFA, WDHD1, WNT2	2687	organelle part
GO:0005634	7.793e-03	103	131 ADAMTS5, ANGPTL4, ASF1B, ASPM, ATF3, AURKB, BHLHE40, BIRC5, BLM, BUB1, BUB1B, C13orf15, C21orf45, CASP1, CCNA2, CCNE2, CDC14B, CDC20, CDC45L, CDC6, CDC7, CDCA8, CDK2, CDT1, CDYL, CENPE, CENPF, CENPM, CHAF1A, CHAF1B, CPA3, DACT1, DDX11, DEPDC1, DHCR7, DLGAP5, DMD, DSN1, DTL, EGR2, EXO1, EXOSC9, EZH2, FANCG, FBXW7, FOSB, GCH1, GINS1, GINS2, GINS3, GMNN, GNPTAB, HIVEP1, HLX, HMGB2, JARID2, JMJD3, KIAA0586, KIF11, KIF14, KIF20B, KIF22, KIF2C, KIF4A, KLF7, LIG1, LMCD1, LMNB1, LUZP1, MAD2L1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MKI67, NCAPD3, NCAPG, NCAPH, NDC80, NDRG1, NEDD9, NFATC1, NFIL3, NFKB1, NR3C1, NR4A1, NR4A2, NR4A3, NUSAP1, OIP5, ORC1L, ORC6L, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PPL, PRIM1, PRKG1, PSMC3IP, PTHLH, RAD54B, RAD54L, RANGAP1, RBL1, REL, RELB, RFC3, RFC4, RNASEH2A, RUNX1, SGK1, SKIL, SMC2, SOX9, SPC25, SREBF2, SRF, TIMELESS, TNS3, TP53BP2, TPX2, TRIB1, TRIP13, VDR, WDHD1	3059	nucleus
GO:0005875	1.063e-02	2.221	9 CENPE, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A	66	microtubule associated complex
GO:0044430	1.132e-02	14.07	28 AURKB, BUB1, BUB1B, C13orf15, C18orf24, CDC20, CDC45L, CDC6, CENPE, CENPF, CKAP2, DLGAP5, GABARAPL1, GABARAPL3, GTSE1, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LMNB1, NEDD9, NUSAP1, TPX2, TTK	418	cytoskeletal part
GO:0031974	1.163e-02	36.79	57 ANGPTL4, ATF3, BIRC5, BLM, CASP1, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, DDX11, EXOSC9, EZH2, GMNN, HLX, HMGB2, KIF20B, KIF4A, LIG1, LMNB1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MKI67, NFKB1, NR3C1, NR4A1, OIP5, ORC1L, ORC6L, PDGFA, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PRKG1, RBL1, RFC3, RFC4, SOX9, SRF, TNS3, VEGFA, WDHD1	1093	membrane-enclosed lumen
GO:0031012	1.169e-02	5.486	15 ADAMTS5, ANGPTL4, ASPN, COL14A1, COL15A1, COL21A1, ECM2, FGF1, MFAP4, OLFML2A, OMD, PRELP, TNXB, VEGFA, WNT2	163	extracellular matrix
GO:0005874	1.269e-02	4.948	14 CENPE, CKAP2, GABARAPL1, GABARAPL3, GTSE1, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, NUSAP1	147	microtubule
GO:0000922	1.306e-02	0.6732	5 BUB1, CENPF, DLGAP5, KIF11, TPX2	20	spindle pole
GO:0070013	1.376e-02	35.41	55 ANGPTL4, ATF3, BIRC5, BLM, CASP1, CCNA2, CCNE2, CDC20, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, DDX11, EXOSC9, EZH2, GMNN, HLX, HMGB2, KIF20B, KIF4A, LIG1, LMNB1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MKI67, NFKB1, NR3C1, NR4A1, OIP5, ORC1L, ORC6L, PKMYT1, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PRIM1, PRKG1, RBL1, RFC3, RFC4, SOX9, SRF, TNS3, WDHD1	1052	intracellular organelle lumen
GO:0005576	1.515e-02	22.65	39 ADAMTS5, ANGPTL4, ASPN, BMP2, C1R, CCL2, COL14A1, COL15A1, COL21A1, CREG1, CXCL3, DKK2, ECM2, F10, FGF1, FGF7, HBEGF, ICAM1, IL1A, IL1B, IL6, IL8, LIF, MFAP4, OLFML2A, OMD, PDGFA, PDGFD, PRELP, PRSS12, PTHLH, ST3GAL1, SVEP1, THBD, TNFSF4, TNXB, VEGFA, WISP1, WNT2	673	extracellular region
GO:0005578	1.796e-02	5.15	14 ADAMTS5, ANGPTL4, ASPN, COL14A1, COL15A1, COL21A1, ECM2, FGF1, MFAP4, OMD, PRELP, TNXB, VEGFA, WNT2	153	proteinaceous extracellular matrix
GO:0005615	2.726e-02	7.977	18 ANGPTL4, BMP2, CCL2, CXCL3, DKK2, FGF1, HBEGF, ICAM1, IL1A, IL1B, IL6, IL8, LIF, PDGFA, PTHLH, THBD, TNFSF4, VEGFA	237	extracellular space

Id	Pvalue	ExpCount	Count	Size	Term
GO:0003777	4.678e-04	1.16	9 CENPE, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A	37	microtubule motor activity
GO:0003887	2.453e-03	0.5641	6 POLA1, POLA2, POLD1, POLE, POLE2, POLQ	18	DNA-directed DNA polymerase activity
GO:0005515	3.313e-03	141.2	172 ADAMTS5, ADIPOR2, ALDOC, ANGPTL4, ANK2, ASAP2, ASF1B, ASPM, ASPN, ATF3, AURKB, BHLHE40, BIRC5, BLM, BMP2, BMPR2, BUB1B, C13orf15, CASP1, CCL2, CCNA2, CCNE2, CDC14B, CDC20, CDC45L, CDC6, CDC7, CDCA8, CDK2, CDT1, CENPE, CENPF, CHAF1A, CHAF1B, CHMP1B, COL14A1, COL15A1, CREG1, CXCR7, DHCR7, DLGAP5, DMD, DNASE2, DSN1, DTL, DVL3, ECM2, EGR2, ERCC6L, EXO1, EXOSC9, EZH2, F10, FANCG, FBXW7, FCGRT, FGF1, FGF7, FOSB, GABARAPL1, GCH1, GEM, GINS1, GINS2, GMNN, GNPTAB, GPNMB, HBEGF, HIVEP1, HMGB2, ICAM1, IL1A, IL1B, IL6, IL8, INSIG1, JARID2, JHDM1D, KCND3, KIF20B, KIF22, KIF2C, KIF4A, KLF7, LDLR, LIF, LMCD1, LRIG1, MAD2L1, MAGI2, MCM10, MCM2, MCM3, MCM4, MCM5, MCM7, MFAP4, MKI67, MTSS1, NAMPT, NCAPG, NDC80, NDRG1, NEDD9, NFIL3, NFKB1, NR3C1, NR4A1, OIP5, OLFML2A, OMD, ORC1L, ORC6L, PDGFA, PDGFD, PDGFRB, PIK3CD, PKMYT1, PLSCR4, PLXNC1, PMEPA1, POLA1, POLA2, POLD1, POLE, PPL, PPP3CC, PRELP, PRIM1, PRKG1, PSMC3IP, PTHLH, QPRT, RAD54B, RANGAP1, RASGRP1, RBL1, REL, RELB, RFC3, RFC4, RGS2, RHOQ, RRAD, RUNX1, SGK1, SKIL, SMC2, SOX9, SPC25, SREBF2, SRF, STK38L, SVEP1, TACC3, TGFBR1, THBD, TNFAIP6, TNFAIP8, TNFSF4, TNS3, TP53BP2, TPD52L1, TPX2, TRIB1, TRIP13, TTK, VCL, VDR, VEGFA, WISP1, WNT2	4505	protein binding
GO:0034061	5.346e-03	0.6581	6 POLA1, POLA2, POLD1, POLE, POLE2, POLQ	21	DNA polymerase activity
GO:0005524	8.986e-03	25.1	45 ABCA5, ATP13A3, AURKB, BLM, BMPR2, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, DDX11, ERCC6L, HK2, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LIG1, MCM2, MCM3, MCM5, MCM7, MKI67, ORC1L, PDGFRB, PKMYT1, POLQ, PRKG1, RAD54B, RAD54L, RFC4, SGK1, SMC2, STK38L, TGFBR1, TPX2, TRIB1, TRIP13, TTK, UBA7	801	ATP binding
GO:0005125	9.196e-03	2.225	10 BMP2, CCL2, IL1A, IL1B, IL6, IL8, LIF, NAMPT, TNFSF4, VEGFA	71	cytokine activity
GO:0030554	1.000e-02	26.8	47 ABCA5, ATP13A3, AURKB, BLM, BMPR2, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, DDX11, ERCC6L, GALNAC4S-6ST, HK2, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LIG1, MCM2, MCM3, MCM5, MCM7, MKI67, ORC1L, PDGFRB, PKMYT1, POLQ, PRKG1, RAD54B, RAD54L, RFC4, SGK1, SMC2, SQLE, STK38L, TGFBR1, TPX2, TRIB1, TRIP13, TTK, UBA7	855	adenyl nucleotide binding
GO:0032559	1.116e-02	25.39	45 ABCA5, ATP13A3, AURKB, BLM, BMPR2, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, DDX11, ERCC6L, HK2, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LIG1, MCM2, MCM3, MCM5, MCM7, MKI67, ORC1L, PDGFRB, PKMYT1, POLQ, PRKG1, RAD54B, RAD54L, RFC4, SGK1, SMC2, STK38L, TGFBR1, TPX2, TRIB1, TRIP13, TTK, UBA7	810	adenyl ribonucleotide binding
GO:0008083	1.457e-02	2.852	11 BMP2, FGF1, FGF7, HBEGF, IL1A, IL1B, IL6, LIF, PDGFA, PDGFD, VEGFA	91	growth factor activity
GO:0003677	2.833e-02	37.45	58 ATF3, BHLHE40, BLM, DDX11, DNASE2, EGR2, ERCC6L, EXO1, EZH2, FANCG, FOSB, HIVEP1, HIVEP2, HLX, HMGB2, JARID2, JMJD3, KIF15, KIF22, KIF2C, KIF4A, KLF7, LHFP, LIG1, MCM2, MCM3, MCM4, MCM5, MCM7, NFATC1, NFIL3, NFKB1, NR3C1, NR4A1, NR4A2, NR4A3, NUSAP1, ORC1L, ORC6L, POLA1, POLA2, POLD1, POLE, POLE2, POLQ, PSMC3IP, RAD54B, RAD54L, REL, RELB, RFC3, RFC4, RUNX1, SOX9, SREBF2, SRF, VDR, WDHD1	1195	DNA binding
GO:0005102	2.895e-02	12.54	26 ADAMTS5, ANGPTL4, BMP2, CCL2, ECM2, FGF1, FGF7, GPNMB, HBEGF, ICAM1, IL1A, IL1B, IL6, IL8, LIF, MFAP4, MTSS1, NAMPT, PDGFA, PDGFD, PDGFRB, PLXNC1, PTHLH, TGFBR1, TNFSF4, VEGFA	400	receptor binding
GO:0003774	2.909e-02	2.194	9 CENPE, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A	70	motor activity
GO:0017076	3.516e-02	32.88	52 ABCA5, ATP13A3, AURKB, BLM, BMPR2, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, DDX11, ERCC6L, GALNAC4S-6ST, GCH1, GEM, HK2, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LIG1, MCM2, MCM3, MCM5, MCM7, MKI67, ORC1L, PDGFRB, PKMYT1, POLQ, PRKG1, RAB33A, RAD54B, RAD54L, RFC4, RHOQ, RRAD, SGK1, SMC2, SQLE, STK38L, TGFBR1, TPX2, TRIB1, TRIP13, TTK, UBA7	1049	purine nucleotide binding
GO:0032553	3.840e-02	31.4	50 ABCA5, ATP13A3, AURKB, BLM, BMPR2, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, DDX11, ERCC6L, GCH1, GEM, HK2, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LIG1, MCM2, MCM3, MCM5, MCM7, MKI67, ORC1L, PDGFRB, PKMYT1, POLQ, PRKG1, RAB33A, RAD54B, RAD54L, RFC4, RHOQ, RRAD, SGK1, SMC2, STK38L, TGFBR1, TPX2, TRIB1, TRIP13, TTK, UBA7	1002	ribonucleotide binding
GO:0032555	3.840e-02	31.4	50 ABCA5, ATP13A3, AURKB, BLM, BMPR2, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, DDX11, ERCC6L, GCH1, GEM, HK2, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF2C, KIF4A, LIG1, MCM2, MCM3, MCM5, MCM7, MKI67, ORC1L, PDGFRB, PKMYT1, POLQ, PRKG1, RAB33A, RAD54B, RAD54L, RFC4, RHOQ, RRAD, SGK1, SMC2, STK38L, TGFBR1, TPX2, TRIB1, TRIP13, TTK, UBA7	1002	purine ribonucleotide binding

Id	Pvalue	ExpCount	Count	Size	Term
03030	4.087e-10	1.424	15 LIG1, MCM2, MCM3, MCM4, MCM5, MCM7, POLA1, POLA2, POLD1, POLE, POLE2, PRIM1, RFC3, RFC4, RNASEH2A	33	DNA replication
04110	7.206e-07	4.229	20 BUB1, BUB1B, CCNA2, CCNE2, CDC14B, CDC20, CDC45L, CDC6, CDC7, CDK2, MAD2L1, MCM2, MCM3, MCM4, MCM5, MCM7, ORC1L, ORC6L, PKMYT1, RBL1	98	Cell cycle
00100	5.048e-04	0.9926	8 CYP51A1, DHCR7, HMGCR, IDI1, LSS, SC4MOL, SQLE, TM7SF2	23	Biosynthesis of steroids
04060	2.232e-02	4.963	14 BMP2, BMPR2, CCL2, CXCL3, IL1A, IL1B, IL6, IL8, LIF, PDGFA, PDGFRB, TGFBR1, TNFSF4, VEGFA	115	Cytokine-cytokine receptor interaction

No enriched terms

No enriched terms

Entrez genes

ABCA5ATP-binding cassette, sub-family A (ABC1), member 5 (213353_at), score: 0.66 ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif, 5 (219935_at), score: 0.58 ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide (209612_s_at), score: 0.57 ADIPOR2adiponectin receptor 2 (201346_at), score: 0.65 ALDH6A1aldehyde dehydrogenase 6 family, member A1 (221589_s_at), score: 0.59 ALDOCaldolase C, fructose-bisphosphate (202022_at), score: 0.6 ANGPTL4angiopoietin-like 4 (221009_s_at), score: 0.91 ANK2ankyrin 2, neuronal (202920_at), score: 0.79 AQP3aquaporin 3 (Gill blood group) (39248_at), score: 0.65 ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (206414_s_at), score: 0.59 ASF1BASF1 anti-silencing function 1 homolog B (S. cerevisiae) (218115_at), score: -0.85 ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila) (219918_s_at), score: -0.87 ASPNasporin (219087_at), score: 0.59 ATF3activating transcription factor 3 (202672_s_at), score: 0.58 ATP13A3ATPase type 13A3 (219558_at), score: 0.64 AURKBaurora kinase B (209464_at), score: -0.93 B3GNT2UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (219326_s_at), score: 0.74 BHLHE40basic helix-loop-helix family, member e40 (201170_s_at), score: 0.59 BIRC5baculoviral IAP repeat-containing 5 (202095_s_at), score: -0.91 BLMBloom syndrome (205733_at), score: -0.86 BMP2bone morphogenetic protein 2 (205289_at), score: 0.69 BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) (210214_s_at), score: 0.59 BUB1budding uninhibited by benzimidazoles 1 homolog (yeast) (209642_at), score: -0.89 BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast) (203755_at), score: -0.88 C13orf15chromosome 13 open reading frame 15 (218723_s_at), score: 0.58 C14orf1chromosome 14 open reading frame 1 (217188_s_at), score: 0.68 C17orf91chromosome 17 open reading frame 91 (214696_at), score: 0.94 C18orf24chromosome 18 open reading frame 24 (217640_x_at), score: -0.9 C1Rcomplement component 1, r subcomponent (212067_s_at), score: 0.61 C21orf45chromosome 21 open reading frame 45 (219004_s_at), score: -1 C4orf18chromosome 4 open reading frame 18 (219872_at), score: 0.8 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: 0.57 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: 0.6 CCNA2cyclin A2 (203418_at), score: -0.86 CCNE2cyclin E2 (205034_at), score: -0.9 CD302CD302 molecule (203799_at), score: 0.65 CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae) (208022_s_at), score: 0.57 CDC20cell division cycle 20 homolog (S. cerevisiae) (202870_s_at), score: -0.88 CDC45LCDC45 cell division cycle 45-like (S. cerevisiae) (204126_s_at), score: -0.91 CDC6cell division cycle 6 homolog (S. cerevisiae) (203967_at), score: -0.91 CDC7cell division cycle 7 homolog (S. cerevisiae) (204510_at), score: -0.89 CDCA3cell division cycle associated 3 (221436_s_at), score: -0.85 CDCA8cell division cycle associated 8 (221520_s_at), score: -0.89 CDK2cyclin-dependent kinase 2 (204252_at), score: -0.96 CDT1chromatin licensing and DNA replication factor 1 (209832_s_at), score: -0.9 CDYLchromodomain protein, Y-like (203100_s_at), score: 0.61 CENPEcentromere protein E, 312kDa (205046_at), score: -0.85 CENPFcentromere protein F, 350/400ka (mitosin) (207828_s_at), score: -0.86 CENPMcentromere protein M (218741_at), score: -0.94 CHAF1Achromatin assembly factor 1, subunit A (p150) (214426_x_at), score: -0.94 CHAF1Bchromatin assembly factor 1, subunit B (p60) (204775_at), score: -0.87 CHMP1Bchromatin modifying protein 1B (218178_s_at), score: 0.58 CKAP2cytoskeleton associated protein 2 (218252_at), score: -0.94 COL14A1collagen, type XIV, alpha 1 (212865_s_at), score: 0.77 COL15A1collagen, type XV, alpha 1 (203477_at), score: 0.78 COL21A1collagen, type XXI, alpha 1 (208096_s_at), score: 0.69 CORINcorin, serine peptidase (220356_at), score: 0.7 CPA3carboxypeptidase A3 (mast cell) (205624_at), score: 0.83 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: 0.57 CTSOcathepsin O (203758_at), score: 0.7 CXCL3chemokine (C-X-C motif) ligand 3 (207850_at), score: 0.65 CXCR7chemokine (C-X-C motif) receptor 7 (212977_at), score: 0.65 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: 0.77 DACT1dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) (219179_at), score: 0.59 DDX11DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (208149_x_at), score: -0.89 DEPDC1DEP domain containing 1 (220295_x_at), score: -0.91 DHCR77-dehydrocholesterol reductase (201790_s_at), score: 0.79 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: 0.57 DLEU2deleted in lymphocytic leukemia 2 (non-protein coding) (216870_x_at), score: -0.88 DLEU2Ldeleted in lymphocytic leukemia 2-like (215629_s_at), score: -0.93 DLGAP5discs, large (Drosophila) homolog-associated protein 5 (203764_at), score: -0.86 DMDdystrophin (203881_s_at), score: 0.58 DNASE2deoxyribonuclease II, lysosomal (214992_s_at), score: 0.57 DRAMdamage-regulated autophagy modulator (218627_at), score: 0.69 DSN1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) (219512_at), score: -0.98 DTLdenticleless homolog (Drosophila) (218585_s_at), score: -0.9 DVL3dishevelled, dsh homolog 3 (Drosophila) (201908_at), score: 0.57 ECM2extracellular matrix protein 2, female organ and adipocyte specific (206101_at), score: 0.72 EGR2early growth response 2 (Krox-20 homolog, Drosophila) (205249_at), score: 0.77 ENTPD7ectonucleoside triphosphate diphosphohydrolase 7 (220153_at), score: 0.66 ERCC6Lexcision repair cross-complementing rodent repair deficiency, complementation group 6-like (219650_at), score: -0.9 ERI2exoribonuclease 2 (213365_at), score: -0.87 EXO1exonuclease 1 (204603_at), score: -0.85 EXOSC9exosome component 9 (205061_s_at), score: -0.85 EZH2enhancer of zeste homolog 2 (Drosophila) (203358_s_at), score: -0.95 F10coagulation factor X (205620_at), score: 0.75 FABP3fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) (214285_at), score: 0.85 FAM64Afamily with sequence similarity 64, member A (221591_s_at), score: -0.85 FANCGFanconi anemia, complementation group G (203564_at), score: -0.92 FBXW7F-box and WD repeat domain containing 7 (218751_s_at), score: 0.64 FCGRTFc fragment of IgG, receptor, transporter, alpha (218831_s_at), score: 0.61 FGF1fibroblast growth factor 1 (acidic) (205117_at), score: 0.59 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: 0.71 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: 0.81 FRYfurry homolog (Drosophila) (204072_s_at), score: 0.79 GABARAPL1GABA(A) receptor-associated protein like 1 (208868_s_at), score: 0.74 GABARAPL3GABA(A) receptors associated protein like 3 (pseudogene) (211458_s_at), score: 0.68 GALNAC4S-6STB cell RAG associated protein (203066_at), score: 0.7 GCH1GTP cyclohydrolase 1 (204224_s_at), score: 0.73 GDPD5glycerophosphodiester phosphodiesterase domain containing 5 (32502_at), score: 0.62 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: 0.74 GFPT2glutamine-fructose-6-phosphate transaminase 2 (205100_at), score: 0.66 GINS1GINS complex subunit 1 (Psf1 homolog) (206102_at), score: -0.94 GINS2GINS complex subunit 2 (Psf2 homolog) (221521_s_at), score: -0.97 GINS3GINS complex subunit 3 (Psf3 homolog) (45633_at), score: -0.94 GMNNgeminin, DNA replication inhibitor (218350_s_at), score: -0.87 GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (212959_s_at), score: 0.64 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: 0.58 GPR183G protein-coupled receptor 183 (205419_at), score: 0.65 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: 0.64 GSTM1glutathione S-transferase mu 1 (204550_x_at), score: 0.67 GSTM2glutathione S-transferase mu 2 (muscle) (204418_x_at), score: 0.59 GTSE1G-2 and S-phase expressed 1 (204318_s_at), score: -0.89 HBEGFheparin-binding EGF-like growth factor (203821_at), score: 0.64 HIVEP1human immunodeficiency virus type I enhancer binding protein 1 (204512_at), score: 0.78 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: 0.63 HK2hexokinase 2 (202934_at), score: 0.62 HLXH2.0-like homeobox (214438_at), score: 0.63 HMGB2high-mobility group box 2 (208808_s_at), score: -0.86 HMGCR3-hydroxy-3-methylglutaryl-Coenzyme A reductase (202539_s_at), score: 0.65 HMGCS13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) (221750_at), score: 0.67 HMMRhyaluronan-mediated motility receptor (RHAMM) (207165_at), score: -0.86 HSPB3heat shock 27kDa protein 3 (206375_s_at), score: 0.66 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: 0.86 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: 0.87 IL1Ainterleukin 1, alpha (210118_s_at), score: 0.59 IL1Binterleukin 1, beta (39402_at), score: 0.59 IL6interleukin 6 (interferon, beta 2) (205207_at), score: 0.93 IL8interleukin 8 (211506_s_at), score: 0.76 INSIG1insulin induced gene 1 (201627_s_at), score: 0.97 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: 0.64 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: 0.83 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: 0.78 KCND3potassium voltage-gated channel, Shal-related subfamily, member 3 (213832_at), score: 0.73 KIAA0586KIAA0586 (205631_at), score: -0.87 KIAA1644KIAA1644 (52837_at), score: 0.65 KIF11kinesin family member 11 (204444_at), score: -0.91 KIF14kinesin family member 14 (206364_at), score: -0.89 KIF15kinesin family member 15 (219306_at), score: -0.9 KIF18Bkinesin family member 18B (222039_at), score: -0.96 KIF20Bkinesin family member 20B (205235_s_at), score: -0.88 KIF22kinesin family member 22 (202183_s_at), score: -0.9 KIF2Ckinesin family member 2C (209408_at), score: -0.87 KIF4Akinesin family member 4A (218355_at), score: -0.92 KLF7Kruppel-like factor 7 (ubiquitous) (204334_at), score: 0.61 LDLRlow density lipoprotein receptor (202068_s_at), score: 0.67 LHFPlipoma HMGIC fusion partner (218656_s_at), score: 0.67 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: 0.82 LIG1ligase I, DNA, ATP-dependent (202726_at), score: -0.86 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: 0.66 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: 0.97 LMNB1lamin B1 (203276_at), score: -0.89 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: 0.82 LRIG1leucine-rich repeats and immunoglobulin-like domains 1 (211596_s_at), score: 0.62 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (211019_s_at), score: 0.6 LUZP1leucine zipper protein 1 (221832_s_at), score: 0.58 LZTFL1leucine zipper transcription factor-like 1 (218437_s_at), score: 0.61 MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast) (203362_s_at), score: -0.97 MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 (209737_at), score: 0.6 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.76 MCM10minichromosome maintenance complex component 10 (220651_s_at), score: -0.99 MCM2minichromosome maintenance complex component 2 (202107_s_at), score: -0.91 MCM3minichromosome maintenance complex component 3 (201555_at), score: -0.88 MCM4minichromosome maintenance complex component 4 (212141_at), score: -0.87 MCM5minichromosome maintenance complex component 5 (216237_s_at), score: -0.96 MCM7minichromosome maintenance complex component 7 (210983_s_at), score: -0.88 MFAP4microfibrillar-associated protein 4 (212713_at), score: 0.71 MKI67antigen identified by monoclonal antibody Ki-67 (212022_s_at), score: -0.85 MTSS1metastasis suppressor 1 (203037_s_at), score: 0.61 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: 0.67 NCAPD3non-SMC condensin II complex, subunit D3 (212789_at), score: -0.91 NCAPGnon-SMC condensin I complex, subunit G (218663_at), score: -0.89 NCAPHnon-SMC condensin I complex, subunit H (212949_at), score: -0.88 NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae) (204162_at), score: -0.87 NDRG1N-myc downstream regulated 1 (200632_s_at), score: 0.63 NEDD9neural precursor cell expressed, developmentally down-regulated 9 (202149_at), score: 0.63 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: 0.8 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: 0.65 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: 0.66 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: 0.66 NR4A1nuclear receptor subfamily 4, group A, member 1 (202340_x_at), score: 0.74 NR4A2nuclear receptor subfamily 4, group A, member 2 (216248_s_at), score: 0.61 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: 0.89 NUSAP1nucleolar and spindle associated protein 1 (218039_at), score: -0.85 OIP5Opa interacting protein 5 (213599_at), score: -0.86 OLFML2Aolfactomedin-like 2A (213075_at), score: 0.76 OMDosteomodulin (205907_s_at), score: 0.57 ORC1Lorigin recognition complex, subunit 1-like (yeast) (205085_at), score: -0.86 ORC6Lorigin recognition complex, subunit 6 like (yeast) (219105_x_at), score: -0.97 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: 0.72 PDGFDplatelet derived growth factor D (219304_s_at), score: 0.83 PDGFRBplatelet-derived growth factor receptor, beta polypeptide (202273_at), score: 0.69 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: 0.66 PKMYT1protein kinase, membrane associated tyrosine/threonine 1 (204267_x_at), score: -0.88 PLSCR4phospholipid scramblase 4 (218901_at), score: 0.72 PLXNC1plexin C1 (213241_at), score: 0.59 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: 0.82 POLA1polymerase (DNA directed), alpha 1, catalytic subunit (204835_at), score: -0.99 POLA2polymerase (DNA directed), alpha 2 (70kD subunit) (204441_s_at), score: -0.87 POLD1polymerase (DNA directed), delta 1, catalytic subunit 125kDa (203422_at), score: -0.96 POLEpolymerase (DNA directed), epsilon (216026_s_at), score: -0.92 POLE2polymerase (DNA directed), epsilon 2 (p59 subunit) (205909_at), score: -0.92 POLQpolymerase (DNA directed), theta (219510_at), score: -0.87 PPLperiplakin (203407_at), score: 0.94 PPP3CCprotein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (207000_s_at), score: 0.61 PRELPproline/arginine-rich end leucine-rich repeat protein (204223_at), score: 0.82 PRIM1primase, DNA, polypeptide 1 (49kDa) (205053_at), score: -0.94 PRKG1protein kinase, cGMP-dependent, type I (207119_at), score: 0.83 PRSS12protease, serine, 12 (neurotrypsin, motopsin) (205515_at), score: 0.64 PSMC3IPPSMC3 interacting protein (213951_s_at), score: -0.93 PTHLHparathyroid hormone-like hormone (211756_at), score: 0.6 QPRTquinolinate phosphoribosyltransferase (204044_at), score: 0.59 RAB33ARAB33A, member RAS oncogene family (206039_at), score: 0.64 RAD54BRAD54 homolog B (S. cerevisiae) (219494_at), score: -0.94 RAD54LRAD54-like (S. cerevisiae) (204558_at), score: -0.86 RANGAP1Ran GTPase activating protein 1 (212125_at), score: -0.88 RASGRP1RAS guanyl releasing protein 1 (calcium and DAG-regulated) (205590_at), score: 0.72 RBL1retinoblastoma-like 1 (p107) (205296_at), score: -0.85 RCAN2regulator of calcineurin 2 (203498_at), score: 0.66 RELv-rel reticuloendotheliosis viral oncogene homolog (avian) (206036_s_at), score: 0.58 RELBv-rel reticuloendotheliosis viral oncogene homolog B (205205_at), score: 0.61 RFC3replication factor C (activator 1) 3, 38kDa (204128_s_at), score: -0.86 RFC4replication factor C (activator 1) 4, 37kDa (204023_at), score: -0.88 RGS2regulator of G-protein signaling 2, 24kDa (202388_at), score: 0.57 RHOQras homolog gene family, member Q (212119_at), score: 0.61 RNASEH2Aribonuclease H2, subunit A (203022_at), score: -0.89 RRADRas-related associated with diabetes (204802_at), score: 0.61 RUNX1runt-related transcription factor 1 (209360_s_at), score: 0.79 SC4MOLsterol-C4-methyl oxidase-like (209146_at), score: 0.86 SCDstearoyl-CoA desaturase (delta-9-desaturase) (200832_s_at), score: 0.67 SGK1serum/glucocorticoid regulated kinase 1 (201739_at), score: 0.74 SKILSKI-like oncogene (206675_s_at), score: 0.72 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: 0.77 SLC2A14solute carrier family 2 (facilitated glucose transporter), member 14 (222088_s_at), score: 0.76 SLC2A3P1solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 1 (221751_at), score: 0.69 SLC46A3solute carrier family 46, member 3 (214719_at), score: 0.73 SMC2structural maintenance of chromosomes 2 (204240_s_at), score: -0.85 SMOXspermine oxidase (210357_s_at), score: 0.82 SOX9SRY (sex determining region Y)-box 9 (202935_s_at), score: 0.67 SPATA2Lspermatogenesis associated 2-like (214965_at), score: 0.71 SPC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) (209891_at), score: -0.88 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: 0.65 SPSB1splA/ryanodine receptor domain and SOCS box containing 1 (219677_at), score: 0.62 SQLEsqualene epoxidase (213562_s_at), score: 0.93 SREBF2sterol regulatory element binding transcription factor 2 (201247_at), score: 0.73 SRFserum response factor (c-fos serum response element-binding transcription factor) (202401_s_at), score: 0.7 ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (208322_s_at), score: 0.65 STILSCL/TAL1 interrupting locus (205339_at), score: -0.89 STK38Lserine/threonine kinase 38 like (212572_at), score: 0.92 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: 0.82 TACC3transforming, acidic coiled-coil containing protein 3 (218308_at), score: -0.89 TACSTD2tumor-associated calcium signal transducer 2 (202286_s_at), score: 0.73 TGFBR1transforming growth factor, beta receptor 1 (206943_at), score: 0.87 THBDthrombomodulin (203887_s_at), score: 0.69 TIMELESStimeless homolog (Drosophila) (203046_s_at), score: -0.87 TM6SF1transmembrane 6 superfamily member 1 (219892_at), score: 0.68 TM7SF2transmembrane 7 superfamily member 2 (210130_s_at), score: 0.62 TMEM194Atransmembrane protein 194A (212621_at), score: -0.93 TMEM41Btransmembrane protein 41B (212623_at), score: 0.6 TNFAIP6tumor necrosis factor, alpha-induced protein 6 (206026_s_at), score: 0.67 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (210260_s_at), score: 0.58 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: 0.63 TNS3tensin 3 (217853_at), score: 0.58 TNXAtenascin XA pseudogene (213451_x_at), score: 0.65 TNXBtenascin XB (216333_x_at), score: 0.65 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: 0.67 TPD52L1tumor protein D52-like 1 (203786_s_at), score: 0.62 TPX2TPX2, microtubule-associated, homolog (Xenopus laevis) (210052_s_at), score: -0.88 TRAPPC6Atrafficking protein particle complex 6A (204985_s_at), score: 0.58 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: 0.75 TRIP13thyroid hormone receptor interactor 13 (204033_at), score: -0.88 TTC17tetratricopeptide repeat domain 17 (218972_at), score: 0.73 TTKTTK protein kinase (204822_at), score: -0.93 UBA7ubiquitin-like modifier activating enzyme 7 (203281_s_at), score: 0.62 VCLvinculin (200930_s_at), score: 0.69 VDRvitamin D (1,25- dihydroxyvitamin D3) receptor (204255_s_at), score: 0.6 VEGFAvascular endothelial growth factor A (211527_x_at), score: 0.82 WDHD1WD repeat and HMG-box DNA binding protein 1 (216228_s_at), score: -0.89 WISP1WNT1 inducible signaling pathway protein 1 (206796_at), score: 0.58 WNT2wingless-type MMTV integration site family member 2 (205648_at), score: 0.64 WRAP53WD repeat containing, antisense to TP53 (44563_at), score: -0.86 YPEL5yippee-like 5 (Drosophila) (217783_s_at), score: 0.61 YRDCyrdC domain containing (E. coli) (218647_s_at), score: 0.63

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
1Twin.CEL	1	2	DS-twin	hgu133plus2	Down	DS-twin 1
5CTwin.CEL	5	2	DS-twin	hgu133plus2	Down	DS-twin 5
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
E-TABM-263-raw-cel-1515486291.cel	33	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486271.cel	32	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486351.cel	36	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486331.cel	35	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486231.cel	30	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485851.cel	11	6	Cycle	hgu133a2	none	Cycle 1