Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
all
This term is the most general term possible
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
monooxygenase activity
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
all
This term is the most general term possible
A1CFAPOBEC1 complementation factor (220951_s_at), score: -0.92 ACSL6acyl-CoA synthetase long-chain family member 6 (211207_s_at), score: -0.72 ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif, 7 (220705_s_at), score: -0.74 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: -0.74 AIPL1aryl hydrocarbon receptor interacting protein-like 1 (219977_at), score: -0.77 BEANbrain expressed, associated with Nedd4 (214068_at), score: -0.73 BMP10bone morphogenetic protein 10 (208292_at), score: -0.91 BRS3bombesin-like receptor 3 (207369_at), score: -0.73 BTNL3butyrophilin-like 3 (217207_s_at), score: -0.94 C10orf59chromosome 10 open reading frame 59 (220564_at), score: -0.72 C1orf61chromosome 1 open reading frame 61 (205103_at), score: -0.77 C21orf2chromosome 21 open reading frame 2 (203996_s_at), score: -0.86 C8orf17chromosome 8 open reading frame 17 (208266_at), score: -0.76 C8orf60chromosome 8 open reading frame 60 (220712_at), score: -0.83 CASZ1castor zinc finger 1 (220015_at), score: -0.75 CCDC9coiled-coil domain containing 9 (206257_at), score: -0.71 CD53CD53 molecule (203416_at), score: -0.83 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: -0.72 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: -0.87 CHN2chimerin (chimaerin) 2 (207486_x_at), score: -0.75 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (220446_s_at), score: -0.78 CLDN10claudin 10 (205328_at), score: -0.83 CNKSR2connector enhancer of kinase suppressor of Ras 2 (206731_at), score: -0.73 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: -0.85 CTSEcathepsin E (205927_s_at), score: -0.72 CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9 (214421_x_at), score: -0.75 CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1 (1431_at), score: -0.71 DHRS9dehydrogenase/reductase (SDR family) member 9 (219799_s_at), score: -0.81 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: -0.78 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: -0.83 DRD5dopamine receptor D5 (208486_at), score: -0.78 EDAectodysplasin A (211130_x_at), score: -0.83 ENPP4ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function) (204160_s_at), score: -0.75 FGL1fibrinogen-like 1 (205305_at), score: -0.73 FKSG2apoptosis inhibitor (208588_at), score: -0.81 FLRT1fibronectin leucine rich transmembrane protein 1 (210414_at), score: -0.72 FOLH1folate hydrolase (prostate-specific membrane antigen) 1 (217487_x_at), score: -0.71 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: -0.77 GNG4guanine nucleotide binding protein (G protein), gamma 4 (205184_at), score: -0.71 GP1BAglycoprotein Ib (platelet), alpha polypeptide (207389_at), score: -0.74 GPATCH4G patch domain containing 4 (220596_at), score: -0.76 GPR12G protein-coupled receptor 12 (214558_at), score: -0.72 GRHL2grainyhead-like 2 (Drosophila) (219388_at), score: -0.74 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: -0.74 HBBhemoglobin, beta (211696_x_at), score: -0.8 HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (219697_at), score: -0.78 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (207901_at), score: -0.76 IL16interleukin 16 (lymphocyte chemoattractant factor) (209827_s_at), score: -0.73 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: -0.76 KCNQ3potassium voltage-gated channel, KQT-like subfamily, member 3 (206573_at), score: -0.71 KIR3DX1killer cell immunoglobulin-like receptor, three domains, X1 (216428_x_at), score: -0.81 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: -0.9 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (205307_s_at), score: -0.74 LHX3LIM homeobox 3 (221670_s_at), score: -0.85 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: -0.82 LOC80054hypothetical LOC80054 (220465_at), score: -0.78 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: -0.73 LRRN2leucine rich repeat neuronal 2 (216164_at), score: -0.74 MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 (205050_s_at), score: -0.75 MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (203936_s_at), score: -0.73 MMRN2multimerin 2 (219091_s_at), score: -0.98 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: -0.97 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: -0.82 MYO1Amyosin IA (211916_s_at), score: -0.98 N4BP3Nedd4 binding protein 3 (214775_at), score: -0.79 NOTCH4Notch homolog 4 (Drosophila) (205247_at), score: -0.75 NRN1neuritin 1 (218625_at), score: -0.83 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: -0.84 NTRK3neurotrophic tyrosine kinase, receptor, type 3 (217033_x_at), score: -0.86 OR1E2olfactory receptor, family 1, subfamily E, member 2 (208587_s_at), score: -0.79 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: -0.89 OVOL2ovo-like 2 (Drosophila) (211778_s_at), score: -0.8 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: -0.92 PGCprogastricsin (pepsinogen C) (205261_at), score: -0.78 PGK2phosphoglycerate kinase 2 (217009_at), score: -0.89 PIK3IP1phosphoinositide-3-kinase interacting protein 1 (221757_at), score: -0.73 PON1paraoxonase 1 (206344_at), score: -0.72 PPP4R4protein phosphatase 4, regulatory subunit 4 (220672_at), score: -0.79 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: -1 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: -0.88 RETret proto-oncogene (205879_x_at), score: -0.8 RP11-35N6.1plasticity related gene 3 (219732_at), score: -0.86 RP3-377H14.5hypothetical LOC285830 (222279_at), score: -0.77 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: -0.87 S100A14S100 calcium binding protein A14 (218677_at), score: -0.84 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: -0.85 SERPINA1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (211429_s_at), score: -0.81 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: -0.78 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (207095_at), score: -0.83 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: -0.75 SLC26A10solute carrier family 26, member 10 (214951_at), score: -0.78 STAP2signal transducing adaptor family member 2 (221610_s_at), score: -0.72 TAAR2trace amine associated receptor 2 (221394_at), score: -0.73 TACR1tachykinin receptor 1 (208048_at), score: -0.82 TBX21T-box 21 (220684_at), score: -0.94 TBX6T-box 6 (207684_at), score: -0.84 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: -0.88 TSPY1testis specific protein, Y-linked 1 (216374_at), score: -0.73 VGFVGF nerve growth factor inducible (205586_x_at), score: -0.97
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| ctrl a 08-03.CEL | 1 | 1 | DS-CC | hgu133a | none | DS-CC 1 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| E-TABM-263-raw-cel-1515486071.cel | 22 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485651.cel | 1 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
