Under-expression is coded with green,
over-expression with red color.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
MHC class I peptide loading complex
A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
MHC class I peptide loading complex
A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
ABHD14Aabhydrolase domain containing 14A (210006_at), score: 0.57 ACCN2amiloride-sensitive cation channel 2, neuronal (205156_s_at), score: 0.59 AGBL5ATP/GTP binding protein-like 5 (218480_at), score: 0.81 AKAP6A kinase (PRKA) anchor protein 6 (205359_at), score: 0.7 ALDH1A3aldehyde dehydrogenase 1 family, member A3 (203180_at), score: -0.66 AMPHamphiphysin (205257_s_at), score: 0.54 ARNT2aryl-hydrocarbon receptor nuclear translocator 2 (202986_at), score: 0.57 B3GALT4UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 (210205_at), score: 0.57 B3GNT1UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (203188_at), score: 0.71 BAZ1Bbromodomain adjacent to zinc finger domain, 1B (208445_s_at), score: -0.53 BCL7BB-cell CLL/lymphoma 7B (202518_at), score: -0.55 BST1bone marrow stromal cell antigen 1 (205715_at), score: 0.56 BTDbiotinidase (204167_at), score: 0.72 BTN3A1butyrophilin, subfamily 3, member A1 (209770_at), score: 0.6 BTN3A2butyrophilin, subfamily 3, member A2 (209846_s_at), score: 0.72 C10orf116chromosome 10 open reading frame 116 (203571_s_at), score: 0.58 C14orf94chromosome 14 open reading frame 94 (218383_at), score: 0.62 C15orf5chromosome 15 open reading frame 5 (208109_s_at), score: -0.65 C1orf115chromosome 1 open reading frame 115 (218546_at), score: -0.66 C4orf30chromosome 4 open reading frame 30 (219717_at), score: 0.58 C4orf31chromosome 4 open reading frame 31 (219747_at), score: 0.55 C7orf58chromosome 7 open reading frame 58 (220032_at), score: 0.64 C9orf125chromosome 9 open reading frame 125 (213386_at), score: 0.54 C9orf127chromosome 9 open reading frame 127 (207839_s_at), score: 1 CALB2calbindin 2 (205428_s_at), score: -0.54 CDH8cadherin 8, type 2 (217574_at), score: 0.76 CHAC1ChaC, cation transport regulator homolog 1 (E. coli) (219270_at), score: -0.56 CHST7carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 (206756_at), score: 0.69 CLEC11AC-type lectin domain family 11, member A (211709_s_at), score: 0.54 CLGNcalmegin (205830_at), score: -0.54 CRELD1cysteine-rich with EGF-like domains 1 (203368_at), score: 0.54 CRYBB2crystallin, beta B2 (206777_s_at), score: -0.53 CRYL1crystallin, lambda 1 (220753_s_at), score: 0.75 CSTAcystatin A (stefin A) (204971_at), score: -0.52 CTPS2CTP synthase II (219080_s_at), score: 0.55 CTSOcathepsin O (203758_at), score: 0.55 CYP26B1cytochrome P450, family 26, subfamily B, polypeptide 1 (219825_at), score: -0.69 DAPK1death-associated protein kinase 1 (203139_at), score: -0.52 DBC1deleted in bladder cancer 1 (205818_at), score: -0.84 DDIT3DNA-damage-inducible transcript 3 (209383_at), score: -0.66 DHRS1dehydrogenase/reductase (SDR family) member 1 (213279_at), score: 0.57 DIAPH2diaphanous homolog 2 (Drosophila) (205603_s_at), score: 0.54 DIO2deiodinase, iodothyronine, type II (203699_s_at), score: -0.53 DKK3dickkopf homolog 3 (Xenopus laevis) (202196_s_at), score: 0.54 DNAJC4DnaJ (Hsp40) homolog, subfamily C, member 4 (206782_s_at), score: 0.64 DPYSL4dihydropyrimidinase-like 4 (205493_s_at), score: -0.57 EGFL6EGF-like-domain, multiple 6 (219454_at), score: -0.87 EIF4Heukaryotic translation initiation factor 4H (206621_s_at), score: -0.57 ELTD1EGF, latrophilin and seven transmembrane domain containing 1 (219134_at), score: -0.54 ENDOD1endonuclease domain containing 1 (212573_at), score: 0.68 F10coagulation factor X (205620_at), score: 0.72 FAM13Bfamily with sequence similarity 13, member B (218518_at), score: -0.71 FGD6FYVE, RhoGEF and PH domain containing 6 (219901_at), score: 0.59 FGF9fibroblast growth factor 9 (glia-activating factor) (206404_at), score: -0.89 FIG4FIG4 homolog (S. cerevisiae) (203656_at), score: 0.54 FLGfilaggrin (215704_at), score: -0.66 FMODfibromodulin (202709_at), score: -0.52 GABREgamma-aminobutyric acid (GABA) A receptor, epsilon (204537_s_at), score: -0.68 GBP2guanylate binding protein 2, interferon-inducible (202748_at), score: 0.58 GCNT1glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase) (205505_at), score: 0.6 GDF15growth differentiation factor 15 (221577_x_at), score: -0.53 GDPD5glycerophosphodiester phosphodiesterase domain containing 5 (32502_at), score: 0.63 GLRBglycine receptor, beta (205280_at), score: 0.64 GOLSYNGolgi-localized protein (218692_at), score: -0.85 GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) (208813_at), score: -0.56 GSTM4glutathione S-transferase mu 4 (204149_s_at), score: 0.54 GSTT2glutathione S-transferase theta 2 (205439_at), score: 0.67 GTF2A1Lgeneral transcription factor IIA, 1-like (213413_at), score: 0.54 GTPBP2GTP binding protein 2 (221050_s_at), score: -0.59 HHLA3HERV-H LTR-associating 3 (220387_s_at), score: 0.63 HOXA7homeobox A7 (206848_at), score: -0.66 HSPB3heat shock 27kDa protein 3 (206375_s_at), score: 0.73 ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein (208937_s_at), score: -0.7 IFFO1intermediate filament family orphan 1 (36030_at), score: 0.55 IGBP1immunoglobulin (CD79A) binding protein 1 (202105_at), score: 0.56 IGF1insulin-like growth factor 1 (somatomedin C) (209541_at), score: -0.77 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: -0.52 IL27RAinterleukin 27 receptor, alpha (205926_at), score: 0.81 IL7interleukin 7 (206693_at), score: -0.55 ITGB8integrin, beta 8 (211488_s_at), score: -0.55 ITIH5inter-alpha (globulin) inhibitor H5 (219064_at), score: -0.78 KCTD15potassium channel tetramerisation domain containing 15 (218553_s_at), score: -0.69 KLF5Kruppel-like factor 5 (intestinal) (209212_s_at), score: 0.76 LEPRleptin receptor (209894_at), score: 0.64 LEPREL2leprecan-like 2 (204854_at), score: 0.66 LETMD1LETM1 domain containing 1 (207170_s_at), score: 0.58 LHPPphospholysine phosphohistidine inorganic pyrophosphate phosphatase (218523_at), score: 0.65 LMF1lipase maturation factor 1 (219135_s_at), score: 0.67 LMOD1leiomodin 1 (smooth muscle) (203766_s_at), score: 0.66 LPCAT4lysophosphatidylcholine acyltransferase 4 (40472_at), score: 0.64 LUZP1leucine zipper protein 1 (221832_s_at), score: 0.57 MATN2matrilin 2 (202350_s_at), score: 0.58 MFAP3Lmicrofibrillar-associated protein 3-like (205442_at), score: -0.55 MR1major histocompatibility complex, class I-related (207565_s_at), score: 0.64 N4BP2L1NEDD4 binding protein 2-like 1 (213375_s_at), score: 0.55 NBEAneurobeachin (221207_s_at), score: -0.53 NDUFA2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa (213550_s_at), score: 0.65 NME3non-metastatic cells 3, protein expressed in (204862_s_at), score: 0.79 NOTCH3Notch homolog 3 (Drosophila) (203238_s_at), score: 0.58 NRCAMneuronal cell adhesion molecule (204105_s_at), score: -0.92 OBFC1oligonucleotide/oligosaccharide-binding fold containing 1 (219100_at), score: 0.65 OCEL1occludin/ELL domain containing 1 (205441_at), score: 0.7 PALLDpalladin, cytoskeletal associated protein (200906_s_at), score: 0.58 PAPPA2pappalysin 2 (213332_at), score: -0.68 PCCApropionyl Coenzyme A carboxylase, alpha polypeptide (203860_at), score: 0.58 PCYOX1Lprenylcysteine oxidase 1 like (218953_s_at), score: 0.64 PDGFCplatelet derived growth factor C (218718_at), score: 0.64 PEX6peroxisomal biogenesis factor 6 (204545_at), score: 0.68 PGPEP1pyroglutamyl-peptidase I (219891_at), score: -0.54 PLGLB2plasminogen-like B2 (205871_at), score: -0.72 PPP2R5Aprotein phosphatase 2, regulatory subunit B', alpha isoform (202187_s_at), score: 0.54 PRELPproline/arginine-rich end leucine-rich repeat protein (204223_at), score: 0.7 PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (209040_s_at), score: 0.53 PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (204279_at), score: 0.66 PTERphosphotriesterase related (218967_s_at), score: -0.58 PYCARDPYD and CARD domain containing (221666_s_at), score: 0.57 RAGErenal tumor antigen (205130_at), score: 0.58 RALGPS2Ral GEF with PH domain and SH3 binding motif 2 (220338_at), score: -0.69 SAMD14sterile alpha motif domain containing 14 (213866_at), score: 0.54 SCG5secretogranin V (7B2 protein) (203889_at), score: 0.6 SCN1Bsodium channel, voltage-gated, type I, beta (205508_at), score: 0.55 SLC17A5solute carrier family 17 (anion/sugar transporter), member 5 (221041_s_at), score: 0.54 SLC22A17solute carrier family 22, member 17 (218675_at), score: 0.54 SLC27A3solute carrier family 27 (fatty acid transporter), member 3 (222217_s_at), score: 0.57 SLC46A3solute carrier family 46, member 3 (214719_at), score: 0.64 SLC4A2solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) (202111_at), score: -0.56 SLC6A9solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (207043_s_at), score: -0.63 SPINT2serine peptidase inhibitor, Kunitz type, 2 (210715_s_at), score: 0.63 SPON1spondin 1, extracellular matrix protein (209436_at), score: -0.92 STAG1stromal antigen 1 (202293_at), score: -0.55 STARD5StAR-related lipid transfer (START) domain containing 5 (213820_s_at), score: 0.83 STAT4signal transducer and activator of transcription 4 (206118_at), score: 0.65 SUPT3Hsuppressor of Ty 3 homolog (S. cerevisiae) (206506_s_at), score: 0.57 SV2Asynaptic vesicle glycoprotein 2A (203069_at), score: 0.56 SYNE1spectrin repeat containing, nuclear envelope 1 (209447_at), score: -0.53 TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (202307_s_at), score: 0.63 TAPBPTAP binding protein (tapasin) (208829_at), score: 0.6 TBL2transducin (beta)-like 2 (212685_s_at), score: -0.54 TBX1T-box 1 (211273_s_at), score: 0.67 TCTN3tectonic family member 3 (212121_at), score: 0.54 THYN1thymocyte nuclear protein 1 (218491_s_at), score: 0.59 TM4SF20transmembrane 4 L six family member 20 (220639_at), score: 0.56 TMEM176Btransmembrane protein 176B (220532_s_at), score: -0.59 TMEM187transmembrane protein 187 (204340_at), score: 0.65 TNFSF12tumor necrosis factor (ligand) superfamily, member 12 (205611_at), score: 0.54 TRAPPC6Atrafficking protein particle complex 6A (204985_s_at), score: 0.7 TRIB3tribbles homolog 3 (Drosophila) (218145_at), score: -0.55 UBA7ubiquitin-like modifier activating enzyme 7 (203281_s_at), score: 0.67 UCP2uncoupling protein 2 (mitochondrial, proton carrier) (208998_at), score: 0.67 VAMP1vesicle-associated membrane protein 1 (synaptobrevin 1) (213326_at), score: 0.81 VCAM1vascular cell adhesion molecule 1 (203868_s_at), score: 0.67 VDRvitamin D (1,25- dihydroxyvitamin D3) receptor (204255_s_at), score: -0.58 WWC1WW and C2 domain containing 1 (213085_s_at), score: 0.58 ZMIZ1zinc finger, MIZ-type containing 1 (212124_at), score: -0.54 ZNF37Bzinc finger protein 37B (215358_x_at), score: -0.52
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| D890_WBS.CEL | 13 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| 10590_WBS.CEL | 2 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| F055_WBS.CEL | 14 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| H652_WBS.CEL | 17 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| F223_WBS.CEL | 15 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| F348_WBS.CEL | 16 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
