Under-expression is coded with green,
over-expression with red color.
DNA replication
The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.
cell cycle checkpoint
The cell cycle regulatory process by which progression through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage.
M phase of mitotic cell cycle
A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.
mitotic cell cycle
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
M phase
A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division.
nuclear division
A process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
DNA synthesis during DNA repair
Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
regulation of protein amino acid phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
positive regulation of protein amino acid phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
response to molecule of bacterial origin
A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
regulation of cell cycle
Any process that modulates the rate or extent of progression through the cell cycle.
cellular alcohol metabolic process
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
DNA metabolic process
The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
DNA-dependent DNA replication
The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.
DNA replication initiation
The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.
DNA repair
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
lipid metabolic process
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
steroid biosynthetic process
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
phosphorus metabolic process
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
phosphate metabolic process
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
response to DNA damage stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
organelle organization
A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
cell cycle
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
mitosis
A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
mitotic cell cycle checkpoint
A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
regulation of mitotic cell cycle
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
steroid metabolic process
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
cell proliferation
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
lipid biosynthetic process
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
biosynthetic process
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
response to biotic stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
response to other organism
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
response to bacterium
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
regulation of biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
positive regulation of biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of macromolecule biosynthetic process
Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
positive regulation of macromolecule biosynthetic process
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
positive regulation of phosphorus metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
cellular component organization
A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component.
sterol metabolic process
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
sterol biosynthetic process
The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
phosphorylation
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
peptidyl-serine phosphorylation
The posttranslational phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
peptidyl-amino acid modification
The alteration of an amino acid residue in a peptide.
peptidyl-serine modification
The modification of peptidyl-serine.
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
regulation of phosphate metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
cell cycle process
A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
cell cycle phase
A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cellular biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
positive regulation of cellular biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
regulation of protein modification process
Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
positive regulation of protein modification process
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
regulation of cellular protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
regulation of peptidyl-serine phosphorylation
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.
positive regulation of peptidyl-serine phosphorylation
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
cellular response to stress
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
cellular macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
cellular biopolymer biosynthetic process
The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
cellular response to DNA damage stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
regulation of cell proliferation
Any process that modulates the frequency, rate or extent of cell proliferation.
response to chemical stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
regulation of phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
positive regulation of phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.
biopolymer biosynthetic process
The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.
biopolymer modification
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties.
post-translational protein modification
The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
cellular biosynthetic process
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular lipid metabolic process
The chemical reactions and pathways involving lipids, as carried out by individual cells.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
positive regulation of phosphate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
organelle fission
The creation of two or more organelles by division of one organelle.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of phosphorus metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
regulation of protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
positive regulation of protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
cell division
The process resulting in the physical partitioning and separation of a cell into daughter cells.
S phase
A cell cycle process comprising the steps by which a cell progresses through S phase, the part of the cell cycle during which DNA synthesis takes place.
interphase
A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of chromosome segregation. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.
interphase of mitotic cell cycle
A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.
multi-organism process
Any process by which an organism has an effect on another organism of the same or different species.
cellular response to stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of macromolecule metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cellular response to stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
regulation of biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of macromolecule metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
cellular biosynthetic process
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
cell cycle process
A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cell cycle
Any process that modulates the rate or extent of progression through the cell cycle.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cell proliferation
Any process that modulates the frequency, rate or extent of cell proliferation.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cellular response to stress
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
response to other organism
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
response to molecule of bacterial origin
A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
positive regulation of biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
regulation of macromolecule biosynthetic process
Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
positive regulation of macromolecule biosynthetic process
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of cellular biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
positive regulation of cellular biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
positive regulation of macromolecule biosynthetic process
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
positive regulation of cellular biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cellular biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
regulation of macromolecule biosynthetic process
Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
biopolymer biosynthetic process
The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.
cellular macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
positive regulation of phosphorus metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
regulation of phosphorus metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
steroid metabolic process
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
lipid biosynthetic process
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
cellular lipid metabolic process
The chemical reactions and pathways involving lipids, as carried out by individual cells.
regulation of protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
positive regulation of protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
regulation of mitotic cell cycle
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
cellular response to DNA damage stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
response to molecule of bacterial origin
A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
positive regulation of macromolecule biosynthetic process
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
cellular biopolymer biosynthetic process
The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
positive regulation of cellular biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
steroid biosynthetic process
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
sterol metabolic process
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of phosphorus metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
regulation of cellular protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
DNA metabolic process
The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
cellular biopolymer biosynthetic process
The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
sterol biosynthetic process
The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
regulation of phosphate metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
positive regulation of phosphate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
regulation of cellular protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
mitosis
A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
mitotic cell cycle checkpoint
A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
M phase of mitotic cell cycle
A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.
S phase
A cell cycle process comprising the steps by which a cell progresses through S phase, the part of the cell cycle during which DNA synthesis takes place.
interphase of mitotic cell cycle
A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.
DNA repair
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
DNA replication
The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.
positive regulation of protein modification process
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
positive regulation of phosphate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
regulation of protein modification process
Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
positive regulation of protein modification process
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
DNA synthesis during DNA repair
Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template.
regulation of phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
positive regulation of phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
mitosis
A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
positive regulation of protein amino acid phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
positive regulation of protein amino acid phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
regulation of protein amino acid phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
positive regulation of phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
DNA replication initiation
The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.
regulation of protein amino acid phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
positive regulation of protein amino acid phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
positive regulation of peptidyl-serine phosphorylation
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
peptidyl-serine phosphorylation
The posttranslational phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
regulation of peptidyl-serine phosphorylation
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.
positive regulation of peptidyl-serine phosphorylation
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
nuclear chromosome
A chromosome found in the nucleus of a eukaryotic cell.
condensed chromosome
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
chromosome, centromeric region
The region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
kinetochore
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
condensed chromosome kinetochore
A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.
condensed chromosome, centromeric region
The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
chromatin
The ordered and organized complex of DNA and protein that forms the chromosome.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
nucleus
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
nucleoplasm
That part of the nuclear content other than the chromosomes or the nucleolus.
replication fork
The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
chromosome
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
spindle
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
cytoskeleton
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
microtubule cytoskeleton
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
membrane-enclosed lumen
The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
nuclear lumen
The volume enclosed by the nuclear inner membrane.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
organelle lumen
The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
nuclear replication fork
The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
chromosomal part
Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
nuclear part
Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
cytoskeletal part
Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
nuclear chromosome part
Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
intracellular organelle lumen
An organelle lumen that is part of an intracellular organelle.
all
This term is the most general term possible
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
organelle lumen
The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
intracellular organelle lumen
An organelle lumen that is part of an intracellular organelle.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
kinetochore
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
kinetochore
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
nuclear lumen
The volume enclosed by the nuclear inner membrane.
nuclear chromosome part
Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.
spindle
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
nucleoplasm
That part of the nuclear content other than the chromosomes or the nucleolus.
nuclear part
Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
nuclear chromosome
A chromosome found in the nucleus of a eukaryotic cell.
chromosomal part
Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
cytoskeletal part
Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
kinetochore
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
nuclear replication fork
The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
nuclear chromosome part
Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.
condensed chromosome, centromeric region
The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
spindle
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
condensed chromosome kinetochore
A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.
protein binding
Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
nucleic acid binding
Interacting selectively with any nucleic acid.
DNA binding
Interacting selectively with DNA (deoxyribonucleic acid).
receptor binding
Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
cytokine activity
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
binding
The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
growth factor activity
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
all
This term is the most general term possible
Id | Pvalue | ExpCount | Count | Size | Term |
---|---|---|---|---|---|
03030 | 6.820e-07 | 1.065 | 11 | 33 | DNA replication |
04110 | 1.511e-06 | 3.164 | 17 | 98 | Cell cycle |
00100 | 6.451e-03 | 0.7425 | 6 | 23 | Biosynthesis of steroids |
03410 | 2.191e-02 | 0.9685 | 6 | 30 | Base excision repair |
00900 | 3.742e-02 | 0.1937 | 3 | 6 | Terpenoid biosynthesis |
ABCA5ATP-binding cassette, sub-family A (ABC1), member 5 (213353_at), score: -0.82 ANGPTL4angiopoietin-like 4 (221009_s_at), score: -0.97 ANK2ankyrin 2, neuronal (202920_at), score: -0.73 AQP3aquaporin 3 (Gill blood group) (39248_at), score: -0.93 AREGamphiregulin (205239_at), score: -0.88 ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (206414_s_at), score: -0.74 ASF1BASF1 anti-silencing function 1 homolog B (S. cerevisiae) (218115_at), score: 0.7 ATF3activating transcription factor 3 (202672_s_at), score: -0.75 ATP6V0A2ATPase, H+ transporting, lysosomal V0 subunit a2 (205704_s_at), score: -0.76 AURKBaurora kinase B (209464_at), score: 0.71 B3GNT2UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (219326_s_at), score: -0.98 B4GALT5UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (221485_at), score: -0.71 BARD1BRCA1 associated RING domain 1 (205345_at), score: 0.67 BIRC5baculoviral IAP repeat-containing 5 (202095_s_at), score: 0.65 BLMBloom syndrome (205733_at), score: 0.67 BMP2bone morphogenetic protein 2 (205289_at), score: -0.96 BMP6bone morphogenetic protein 6 (206176_at), score: -0.75 BNC1basonuclin 1 (206581_at), score: -0.79 BUB1budding uninhibited by benzimidazoles 1 homolog (yeast) (209642_at), score: 0.72 BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast) (203755_at), score: 0.67 C17orf91chromosome 17 open reading frame 91 (214696_at), score: -0.92 C18orf24chromosome 18 open reading frame 24 (217640_x_at), score: 0.7 C21orf45chromosome 21 open reading frame 45 (219004_s_at), score: 0.66 CBR3carbonyl reductase 3 (205379_at), score: 0.69 CCNA2cyclin A2 (203418_at), score: 0.69 CCNB2cyclin B2 (202705_at), score: 0.65 CCNE2cyclin E2 (205034_at), score: 0.69 CCNJcyclin J (219470_x_at), score: -0.83 CDC20cell division cycle 20 homolog (S. cerevisiae) (202870_s_at), score: 0.66 CDC6cell division cycle 6 homolog (S. cerevisiae) (203967_at), score: 0.73 CDC7cell division cycle 7 homolog (S. cerevisiae) (204510_at), score: 0.81 CDCA8cell division cycle associated 8 (221520_s_at), score: 0.68 CDK2cyclin-dependent kinase 2 (204252_at), score: 0.67 CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1) (209112_at), score: 0.66 CDT1chromatin licensing and DNA replication factor 1 (209832_s_at), score: 0.67 CDYLchromodomain protein, Y-like (203100_s_at), score: -0.8 CENPAcentromere protein A (204962_s_at), score: 0.65 CENPFcentromere protein F, 350/400ka (mitosin) (207828_s_at), score: 0.69 CENPIcentromere protein I (214804_at), score: 0.67 CENPMcentromere protein M (218741_at), score: 0.76 CHAF1Achromatin assembly factor 1, subunit A (p150) (214426_x_at), score: 0.69 CHAF1Bchromatin assembly factor 1, subunit B (p60) (204775_at), score: 0.67 CITcitron (rho-interacting, serine/threonine kinase 21) (212801_at), score: 0.66 CKAP2cytoskeleton associated protein 2 (218252_at), score: 0.73 COL21A1collagen, type XXI, alpha 1 (208096_s_at), score: -0.72 CPA3carboxypeptidase A3 (mast cell) (205624_at), score: -0.85 CREB5cAMP responsive element binding protein 5 (205931_s_at), score: -0.72 CXCL3chemokine (C-X-C motif) ligand 3 (207850_at), score: -0.77 CXCR7chemokine (C-X-C motif) receptor 7 (212977_at), score: -0.93 DDX11DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (208149_x_at), score: 0.71 DEPDC1DEP domain containing 1 (220295_x_at), score: 0.71 DHCR77-dehydrocholesterol reductase (201790_s_at), score: -0.77 DLEU2Ldeleted in lymphocytic leukemia 2-like (215629_s_at), score: 0.66 DSCC1defective in sister chromatid cohesion 1 homolog (S. cerevisiae) (219000_s_at), score: 0.67 DSN1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) (219512_at), score: 0.81 DTLdenticleless homolog (Drosophila) (218585_s_at), score: 0.74 E2F8E2F transcription factor 8 (219990_at), score: 0.67 EGR2early growth response 2 (Krox-20 homolog, Drosophila) (205249_at), score: -0.75 ENTPD7ectonucleoside triphosphate diphosphohydrolase 7 (220153_at), score: -0.97 ERCC6Lexcision repair cross-complementing rodent repair deficiency, complementation group 6-like (219650_at), score: 0.68 EXO1exonuclease 1 (204603_at), score: 0.68 EZH2enhancer of zeste homolog 2 (Drosophila) (203358_s_at), score: 0.74 FABP3fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) (214285_at), score: -0.81 FAM64Afamily with sequence similarity 64, member A (221591_s_at), score: 0.67 FANCGFanconi anemia, complementation group G (203564_at), score: 0.67 FBXW7F-box and WD repeat domain containing 7 (218751_s_at), score: -0.79 FEM1Bfem-1 homolog b (C. elegans) (212367_at), score: -0.74 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: -0.75 FRYfurry homolog (Drosophila) (204072_s_at), score: -0.8 FUT4fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) (209892_at), score: -0.74 GALNAC4S-6STB cell RAG associated protein (203066_at), score: -0.77 GALNT4UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) (220442_at), score: -0.82 GCH1GTP cyclohydrolase 1 (204224_s_at), score: -0.8 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: -0.77 GFPT2glutamine-fructose-6-phosphate transaminase 2 (205100_at), score: -0.85 GINS1GINS complex subunit 1 (Psf1 homolog) (206102_at), score: 0.7 GINS2GINS complex subunit 2 (Psf2 homolog) (221521_s_at), score: 0.73 GINS3GINS complex subunit 3 (Psf3 homolog) (45633_at), score: 0.69 GMNNgeminin, DNA replication inhibitor (218350_s_at), score: 0.67 GPR183G protein-coupled receptor 183 (205419_at), score: -0.93 HBEGFheparin-binding EGF-like growth factor (203821_at), score: -0.8 HELLShelicase, lymphoid-specific (220085_at), score: 0.67 HIVEP1human immunodeficiency virus type I enhancer binding protein 1 (204512_at), score: -0.83 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: -0.79 HJURPHolliday junction recognition protein (218726_at), score: 0.67 HMGB2high-mobility group box 2 (208808_s_at), score: 0.75 HMMRhyaluronan-mediated motility receptor (RHAMM) (207165_at), score: 0.66 HOXA10homeobox A10 (213150_at), score: 0.72 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: -0.95 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: -0.71 IDI2isopentenyl-diphosphate delta isomerase 2 (217631_at), score: -0.8 IL11interleukin 11 (206924_at), score: -0.72 IL1Ainterleukin 1, alpha (210118_s_at), score: -0.88 IL1Binterleukin 1, beta (39402_at), score: -0.95 IL6interleukin 6 (interferon, beta 2) (205207_at), score: -0.86 INSIG1insulin induced gene 1 (201627_s_at), score: -0.9 ITGB3BPintegrin beta 3 binding protein (beta3-endonexin) (205176_s_at), score: 0.65 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: -0.77 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: -0.93 JMJD6jumonji domain containing 6 (212722_s_at), score: -0.78 KCND3potassium voltage-gated channel, Shal-related subfamily, member 3 (213832_at), score: -0.74 KCNG1potassium voltage-gated channel, subfamily G, member 1 (214595_at), score: -0.76 KIAA0586KIAA0586 (205631_at), score: 0.67 KIAA1644KIAA1644 (52837_at), score: -0.77 KIF11kinesin family member 11 (204444_at), score: 0.67 KIF15kinesin family member 15 (219306_at), score: 0.68 KIF18Bkinesin family member 18B (222039_at), score: 0.76 KIF22kinesin family member 22 (202183_s_at), score: 0.67 KIF4Akinesin family member 4A (218355_at), score: 0.71 KLF7Kruppel-like factor 7 (ubiquitous) (204334_at), score: -0.79 LAMC2laminin, gamma 2 (202267_at), score: -0.82 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: -0.92 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: -0.78 LMNB1lamin B1 (203276_at), score: 0.69 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: -0.82 LRRFIP1leucine rich repeat (in FLII) interacting protein 1 (201861_s_at), score: -0.72 LUZP1leucine zipper protein 1 (221832_s_at), score: -0.74 MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast) (203362_s_at), score: 0.7 MCM10minichromosome maintenance complex component 10 (220651_s_at), score: 0.74 MCM2minichromosome maintenance complex component 2 (202107_s_at), score: 0.69 MCM4minichromosome maintenance complex component 4 (212141_at), score: 0.66 MCM5minichromosome maintenance complex component 5 (216237_s_at), score: 0.7 MCM7minichromosome maintenance complex component 7 (210983_s_at), score: 0.66 MDM1Mdm1 nuclear protein homolog (mouse) (213761_at), score: 0.69 MLF1IPMLF1 interacting protein (218883_s_at), score: 0.65 MTSS1metastasis suppressor 1 (203037_s_at), score: -0.76 MVDmevalonate (diphospho) decarboxylase (203027_s_at), score: -0.72 MYBL1v-myb myeloblastosis viral oncogene homolog (avian)-like 1 (213906_at), score: 0.66 MYO1Emyosin IE (203072_at), score: -0.76 NCAPGnon-SMC condensin I complex, subunit G (218663_at), score: 0.66 NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae) (204162_at), score: 0.65 NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 1 (208093_s_at), score: -0.73 NEIL3nei endonuclease VIII-like 3 (E. coli) (219502_at), score: 0.68 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: -0.83 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: -0.74 NR4A1nuclear receptor subfamily 4, group A, member 1 (202340_x_at), score: -0.86 NR4A2nuclear receptor subfamily 4, group A, member 2 (216248_s_at), score: -0.82 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: -0.89 NUPL1nucleoporin like 1 (204435_at), score: -0.73 OIP5Opa interacting protein 5 (213599_at), score: 0.7 ORC6Lorigin recognition complex, subunit 6 like (yeast) (219105_x_at), score: 0.73 PANK3pantothenate kinase 3 (218433_at), score: -0.77 PANX1pannexin 1 (204715_at), score: -0.77 PARP2poly (ADP-ribose) polymerase 2 (214086_s_at), score: 0.7 PHLPPLPH domain and leucine rich repeat protein phosphatase-like (213407_at), score: -0.75 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: -0.81 PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alpha (207391_s_at), score: -0.73 PLXNC1plexin C1 (213241_at), score: -0.8 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: -0.9 POLA1polymerase (DNA directed), alpha 1, catalytic subunit (204835_at), score: 0.73 POLD1polymerase (DNA directed), delta 1, catalytic subunit 125kDa (203422_at), score: 0.71 POLD3polymerase (DNA-directed), delta 3, accessory subunit (212836_at), score: 0.71 POLE2polymerase (DNA directed), epsilon 2 (p59 subunit) (205909_at), score: 0.72 PPP3CCprotein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (207000_s_at), score: -0.93 PRIM1primase, DNA, polypeptide 1 (49kDa) (205053_at), score: 0.79 PRKG1protein kinase, cGMP-dependent, type I (207119_at), score: -0.79 PSMC3IPPSMC3 interacting protein (213951_s_at), score: 0.72 PTHLHparathyroid hormone-like hormone (211756_at), score: -0.87 RAD51AP1RAD51 associated protein 1 (204146_at), score: 0.66 RAD54BRAD54 homolog B (S. cerevisiae) (219494_at), score: 0.7 RASGRP1RAS guanyl releasing protein 1 (calcium and DAG-regulated) (205590_at), score: -0.94 RASSF8Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 (207754_at), score: -0.83 RELv-rel reticuloendotheliosis viral oncogene homolog (avian) (206036_s_at), score: -0.82 RELBv-rel reticuloendotheliosis viral oncogene homolog B (205205_at), score: -0.88 RFC3replication factor C (activator 1) 3, 38kDa (204127_at), score: 0.69 RICSRho GTPase-activating protein (203431_s_at), score: -0.72 RNASEH2Aribonuclease H2, subunit A (203022_at), score: 0.68 RUNX1runt-related transcription factor 1 (209360_s_at), score: -0.78 SC4MOLsterol-C4-methyl oxidase-like (209146_at), score: -0.85 SCDstearoyl-CoA desaturase (delta-9-desaturase) (200832_s_at), score: -0.75 SEC14L2SEC14-like 2 (S. cerevisiae) (204541_at), score: -0.74 SKILSKI-like oncogene (206675_s_at), score: -0.93 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: -0.88 SLC2A14solute carrier family 2 (facilitated glucose transporter), member 14 (222088_s_at), score: -0.83 SLC2A3P1solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 1 (221751_at), score: -0.74 SMC2structural maintenance of chromosomes 2 (204240_s_at), score: 0.67 SMOXspermine oxidase (210357_s_at), score: -0.8 SOX9SRY (sex determining region Y)-box 9 (202935_s_at), score: -0.81 SPATA2Lspermatogenesis associated 2-like (214965_at), score: -0.87 SPSB1splA/ryanodine receptor domain and SOCS box containing 1 (219677_at), score: -0.76 SQLEsqualene epoxidase (213562_s_at), score: -0.85 SRFserum response factor (c-fos serum response element-binding transcription factor) (202401_s_at), score: -0.82 SS18L1synovial sarcoma translocation gene on chromosome 18-like 1 (213140_s_at), score: -0.75 ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (208322_s_at), score: -0.86 STK38Lserine/threonine kinase 38 like (212572_at), score: -1 TACC3transforming, acidic coiled-coil containing protein 3 (218308_at), score: 0.66 TACSTD2tumor-associated calcium signal transducer 2 (202286_s_at), score: -0.94 TDGthymine-DNA glycosylase (203743_s_at), score: -0.71 TGFBR1transforming growth factor, beta receptor 1 (206943_at), score: -0.94 THBDthrombomodulin (203887_s_at), score: -0.87 TIMELESStimeless homolog (Drosophila) (203046_s_at), score: 0.67 TMEM194Atransmembrane protein 194A (212621_at), score: 0.76 TNFAIP3tumor necrosis factor, alpha-induced protein 3 (202644_s_at), score: -0.78 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: -0.87 TPX2TPX2, microtubule-associated, homolog (Xenopus laevis) (210052_s_at), score: 0.68 TRAF4TNF receptor-associated factor 4 (202871_at), score: -0.72 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: -0.73 TRPC6transient receptor potential cation channel, subfamily C, member 6 (217287_s_at), score: -0.85 TTC17tetratricopeptide repeat domain 17 (218972_at), score: -0.85 TTKTTK protein kinase (204822_at), score: 0.75 TXNIPthioredoxin interacting protein (201008_s_at), score: 0.87 URB2URB2 ribosome biogenesis 2 homolog (S. cerevisiae) (205284_at), score: -0.75 VCLvinculin (200930_s_at), score: -0.88 VEGFAvascular endothelial growth factor A (211527_x_at), score: -0.8 WEE1WEE1 homolog (S. pombe) (212533_at), score: 0.75 YOD1YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) (215150_at), score: -0.83 YRDCyrdC domain containing (E. coli) (218647_s_at), score: -0.86 ZBED4zinc finger, BED-type containing 4 (204799_at), score: -0.77 ZNF672zinc finger protein 672 (218068_s_at), score: -0.8
Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
---|---|---|---|---|---|---|
E-TABM-263-raw-cel-1515485851.cel | 11 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
E-TABM-263-raw-cel-1515486231.cel | 30 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
E-TABM-263-raw-cel-1515486351.cel | 36 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
E-TABM-263-raw-cel-1515486331.cel | 35 | 6 | Cycle | hgu133a2 | none | Cycle 1 |