Under-expression is coded with green,
over-expression with red color.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
cellular aldehyde metabolic process
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
aldehyde dehydrogenase (NAD) activity
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
aldo-keto reductase activity
Catalysis of the NADPH-dependent reduction of carbonyl compounds.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
oxidoreductase activity, acting on CH-OH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
oxidoreductase activity, acting on the aldehyde or oxo group of donors
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-CH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.
all
This term is the most general term possible
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 00980 | 1.531e-02 | 0.5565 | 5 | 37 | Metabolism of xenobiotics by cytochrome P450 |
ABCG2ATP-binding cassette, sub-family G (WHITE), member 2 (209735_at), score: -0.56 ACSL5acyl-CoA synthetase long-chain family member 5 (218322_s_at), score: -0.55 AKAP2A kinase (PRKA) anchor protein 2 (202759_s_at), score: 0.64 AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase) (206561_s_at), score: -0.9 AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (204151_x_at), score: -0.59 AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) (209699_x_at), score: -0.63 AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (209160_at), score: -0.62 ALDH1A1aldehyde dehydrogenase 1 family, member A1 (212224_at), score: 0.56 ALDH3A1aldehyde dehydrogenase 3 family, memberA1 (205623_at), score: -0.65 ALDH3A2aldehyde dehydrogenase 3 family, member A2 (202053_s_at), score: -0.56 ARMCX1armadillo repeat containing, X-linked 1 (218694_at), score: 0.6 ASB9ankyrin repeat and SOCS box-containing 9 (205673_s_at), score: -0.56 BIRC3baculoviral IAP repeat-containing 3 (210538_s_at), score: -0.52 BMP7bone morphogenetic protein 7 (209590_at), score: -0.65 C14orf169chromosome 14 open reading frame 169 (219526_at), score: 0.74 C20orf39chromosome 20 open reading frame 39 (219310_at), score: -0.72 CAND2cullin-associated and neddylation-dissociated 2 (putative) (213547_at), score: 0.62 CD24CD24 molecule (209771_x_at), score: -0.6 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (205532_s_at), score: -0.55 CELSR1cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) (41660_at), score: -0.78 CELSR3cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) (40020_at), score: -0.74 CFIcomplement factor I (203854_at), score: -0.55 COL3A1collagen, type III, alpha 1 (215076_s_at), score: 0.61 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: -0.52 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: -0.65 DLX4distal-less homeobox 4 (208216_at), score: -0.59 EGLN3egl nine homolog 3 (C. elegans) (219232_s_at), score: -0.61 EIF4A1eukaryotic translation initiation factor 4A, isoform 1 (211787_s_at), score: -0.52 EMP1epithelial membrane protein 1 (201325_s_at), score: 0.63 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (202017_at), score: -0.55 FAF1Fas (TNFRSF6) associated factor 1 (218080_x_at), score: 0.57 FAM174Bfamily with sequence similarity 174, member B (51158_at), score: 0.74 FAM46Cfamily with sequence similarity 46, member C (220306_at), score: 0.6 FAM65Bfamily with sequence similarity 65, member B (209829_at), score: 0.61 FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32) (203561_at), score: -0.72 FGF13fibroblast growth factor 13 (205110_s_at), score: -0.62 FLJ10357hypothetical protein FLJ10357 (58780_s_at), score: 0.56 FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (222033_s_at), score: 0.62 FOXG1forkhead box G1 (206018_at), score: -0.58 GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 2 (207014_at), score: -0.64 GAL3ST4galactose-3-O-sulfotransferase 4 (219815_at), score: 0.64 GALCgalactosylceramidase (204417_at), score: 0.61 GCLCglutamate-cysteine ligase, catalytic subunit (202923_s_at), score: -0.52 GRAMD3GRAM domain containing 3 (218706_s_at), score: 0.6 GREM1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) (218469_at), score: 1 HEY1hairy/enhancer-of-split related with YRPW motif 1 (44783_s_at), score: -0.58 HHIPL2HHIP-like 2 (220283_at), score: -0.58 HLA-DRB1major histocompatibility complex, class II, DR beta 1 (209312_x_at), score: -0.59 IGSF3immunoglobulin superfamily, member 3 (202421_at), score: -0.85 IL23Ainterleukin 23, alpha subunit p19 (211796_s_at), score: 0.63 IPWimprinted in Prader-Willi syndrome (non-protein coding) (221974_at), score: 0.61 ISL1ISL LIM homeobox 1 (206104_at), score: 0.6 KYNUkynureninase (L-kynurenine hydrolase) (217388_s_at), score: -0.99 LAPTM5lysosomal multispanning membrane protein 5 (201721_s_at), score: -0.62 LEF1lymphoid enhancer-binding factor 1 (221558_s_at), score: -0.78 LPPR4plasticity related gene 1 (213496_at), score: 0.57 LUMlumican (201744_s_at), score: 0.73 LYPD1LY6/PLAUR domain containing 1 (212909_at), score: -0.53 MED31mediator complex subunit 31 (219318_x_at), score: -0.52 MLF1myeloid leukemia factor 1 (204784_s_at), score: -0.54 MLLT3myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (204918_s_at), score: 0.61 MPPED2metallophosphoesterase domain containing 2 (205413_at), score: -0.88 MYO1Bmyosin IB (212364_at), score: 0.76 NDRG1N-myc downstream regulated 1 (200632_s_at), score: -0.59 NESnestin (218678_at), score: 0.56 NPTX1neuronal pentraxin I (204684_at), score: -0.66 NRN1neuritin 1 (218625_at), score: -0.52 NT5E5'-nucleotidase, ecto (CD73) (203939_at), score: 0.57 PCLOpiccolo (presynaptic cytomatrix protein) (213558_at), score: -0.61 PDGFRAplatelet-derived growth factor receptor, alpha polypeptide (203131_at), score: 0.63 PDLIM4PDZ and LIM domain 4 (214175_x_at), score: 0.59 PEX5peroxisomal biogenesis factor 5 (203244_at), score: -0.55 PFDN2prefoldin subunit 2 (218336_at), score: -0.52 PLCG1phospholipase C, gamma 1 (202789_at), score: -0.52 PLK2polo-like kinase 2 (Drosophila) (201939_at), score: -0.54 PSTPIP2proline-serine-threonine phosphatase interacting protein 2 (219938_s_at), score: 0.65 PTPRDprotein tyrosine phosphatase, receptor type, D (214043_at), score: 0.57 RARBretinoic acid receptor, beta (205080_at), score: -0.62 RBM47RNA binding motif protein 47 (218035_s_at), score: -0.54 RIPK4receptor-interacting serine-threonine kinase 4 (221215_s_at), score: -0.71 RND3Rho family GTPase 3 (212724_at), score: 0.64 S100A4S100 calcium binding protein A4 (203186_s_at), score: 0.56 SAMD4Asterile alpha motif domain containing 4A (212845_at), score: 0.57 SCRIBscribbled homolog (Drosophila) (212556_at), score: 0.58 SERPINB9serpin peptidase inhibitor, clade B (ovalbumin), member 9 (209723_at), score: 0.62 SH3BGRSH3 domain binding glutamic acid-rich protein (204979_s_at), score: -0.58 SLC30A1solute carrier family 30 (zinc transporter), member 1 (212907_at), score: 0.6 SLC38A4solute carrier family 38, member 4 (220786_s_at), score: 0.68 SPANXCSPANX family, member C (220217_x_at), score: -0.66 SULF1sulfatase 1 (212353_at), score: 0.58 SULT1A1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (203615_x_at), score: -0.65 SULT1A2sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (207122_x_at), score: -0.59 SYNGR1synaptogyrin 1 (210613_s_at), score: 0.59 TBXA2Rthromboxane A2 receptor (336_at), score: 0.68 TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box) (212761_at), score: 0.63 TEStestis derived transcript (3 LIM domains) (202720_at), score: 0.68 TGFB2transforming growth factor, beta 2 (220407_s_at), score: -0.6 TGFBItransforming growth factor, beta-induced, 68kDa (201506_at), score: -0.54 TGIF2TGFB-induced factor homeobox 2 (216262_s_at), score: -0.59 THBS2thrombospondin 2 (203083_at), score: 0.59 TMEM30Atransmembrane protein 30A (217743_s_at), score: 0.56 TNS1tensin 1 (221748_s_at), score: 0.58 TRPC3transient receptor potential cation channel, subfamily C, member 3 (210814_at), score: -0.58 TSPYL5TSPY-like 5 (213122_at), score: 0.62 TUBB6tubulin, beta 6 (209191_at), score: 0.58 ULK2unc-51-like kinase 2 (C. elegans) (204062_s_at), score: 0.59 VAV3vav 3 guanine nucleotide exchange factor (218807_at), score: -0.67 VCAM1vascular cell adhesion molecule 1 (203868_s_at), score: -0.53 VGLL3vestigial like 3 (Drosophila) (220327_at), score: 0.58 ZNF215zinc finger protein 215 (220214_at), score: 0.59 ZNF518Azinc finger protein 518A (204291_at), score: 0.58
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-4219-raw-cel-1311956457.cel | 14 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956138.cel | 4 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956614.cel | 18 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956321.cel | 9 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956358.cel | 10 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956824.cel | 24 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956178.cel | 6 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
