Under-expression is coded with green,
over-expression with red color.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cell proliferation
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
epithelial cell proliferation
The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.
all
This term is the most general term possible
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
MHC class I peptide loading complex
A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
MHC class I peptide loading complex
A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
AGBL5ATP/GTP binding protein-like 5 (218480_at), score: -0.89 AKAP6A kinase (PRKA) anchor protein 6 (205359_at), score: -0.75 ALDH1A3aldehyde dehydrogenase 1 family, member A3 (203180_at), score: 0.69 ALDH3B1aldehyde dehydrogenase 3 family, member B1 (211004_s_at), score: -0.59 ARNT2aryl-hydrocarbon receptor nuclear translocator 2 (202986_at), score: -0.63 B3GNT1UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (203188_at), score: -0.8 BCL7BB-cell CLL/lymphoma 7B (202518_at), score: 0.54 BST1bone marrow stromal cell antigen 1 (205715_at), score: -0.78 BTDbiotinidase (204167_at), score: -0.75 BTN3A1butyrophilin, subfamily 3, member A1 (209770_at), score: -0.62 BTN3A2butyrophilin, subfamily 3, member A2 (209846_s_at), score: -0.82 BTN3A3butyrophilin, subfamily 3, member A3 (204820_s_at), score: -0.64 C10orf116chromosome 10 open reading frame 116 (203571_s_at), score: -0.72 C15orf5chromosome 15 open reading frame 5 (208109_s_at), score: 0.56 C1orf115chromosome 1 open reading frame 115 (218546_at), score: 0.62 C7orf10chromosome 7 open reading frame 10 (219655_at), score: -0.57 C7orf58chromosome 7 open reading frame 58 (220032_at), score: -0.6 C9orf125chromosome 9 open reading frame 125 (213386_at), score: -0.67 C9orf127chromosome 9 open reading frame 127 (207839_s_at), score: -1 CALB2calbindin 2 (205428_s_at), score: 0.66 CDH8cadherin 8, type 2 (217574_at), score: -0.85 CHST7carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 (206756_at), score: -0.66 CLEC3BC-type lectin domain family 3, member B (205200_at), score: -0.68 CLGNcalmegin (205830_at), score: 0.72 COL8A1collagen, type VIII, alpha 1 (214587_at), score: -0.56 CRELD1cysteine-rich with EGF-like domains 1 (203368_at), score: -0.63 CRYL1crystallin, lambda 1 (220753_s_at), score: -0.82 CTSCcathepsin C (201487_at), score: -0.75 CTSOcathepsin O (203758_at), score: -0.57 CYP26B1cytochrome P450, family 26, subfamily B, polypeptide 1 (219825_at), score: 0.71 DBC1deleted in bladder cancer 1 (205818_at), score: 0.84 DDIT3DNA-damage-inducible transcript 3 (209383_at), score: 0.6 DHRS1dehydrogenase/reductase (SDR family) member 1 (213279_at), score: -0.63 DKK3dickkopf homolog 3 (Xenopus laevis) (202196_s_at), score: -0.66 DMPKdystrophia myotonica-protein kinase (37996_s_at), score: -0.63 DNAJC4DnaJ (Hsp40) homolog, subfamily C, member 4 (206782_s_at), score: -0.7 DPYSL4dihydropyrimidinase-like 4 (205493_s_at), score: 0.56 EDIL3EGF-like repeats and discoidin I-like domains 3 (207379_at), score: -0.68 EGFL6EGF-like-domain, multiple 6 (219454_at), score: 0.81 EIF4Heukaryotic translation initiation factor 4H (206621_s_at), score: 0.65 ELTD1EGF, latrophilin and seven transmembrane domain containing 1 (219134_at), score: 0.61 ENDOD1endonuclease domain containing 1 (212573_at), score: -0.72 ERAP1endoplasmic reticulum aminopeptidase 1 (214012_at), score: -0.64 F10coagulation factor X (205620_at), score: -0.76 FAM13Bfamily with sequence similarity 13, member B (218518_at), score: 0.71 FBXL15F-box and leucine-rich repeat protein 15 (218938_at), score: -0.57 FCHSD2FCH and double SH3 domains 2 (203620_s_at), score: -0.58 FGF1fibroblast growth factor 1 (acidic) (205117_at), score: -0.61 FGF9fibroblast growth factor 9 (glia-activating factor) (206404_at), score: 0.86 FIG4FIG4 homolog (S. cerevisiae) (203656_at), score: -0.56 FLGfilaggrin (215704_at), score: 0.68 FRMD4AFERM domain containing 4A (208476_s_at), score: -0.57 FUCA1fucosidase, alpha-L- 1, tissue (202838_at), score: -0.64 GABREgamma-aminobutyric acid (GABA) A receptor, epsilon (204537_s_at), score: 0.6 GAS7growth arrest-specific 7 (202191_s_at), score: 0.55 GBP2guanylate binding protein 2, interferon-inducible (202748_at), score: -0.61 GDPD5glycerophosphodiester phosphodiesterase domain containing 5 (32502_at), score: -0.66 GFRA1GDNF family receptor alpha 1 (205696_s_at), score: -0.62 GLRBglycine receptor, beta (205280_at), score: -0.68 GOLSYNGolgi-localized protein (218692_at), score: 0.82 GPERG protein-coupled estrogen receptor 1 (210640_s_at), score: 0.63 GRIA1glutamate receptor, ionotropic, AMPA 1 (209793_at), score: 0.57 GSNgelsolin (amyloidosis, Finnish type) (200696_s_at), score: -0.61 GSTM4glutathione S-transferase mu 4 (204149_s_at), score: -0.62 GSTT2glutathione S-transferase theta 2 (205439_at), score: -0.87 GTPBP1GTP binding protein 1 (219357_at), score: -0.58 HDAC9histone deacetylase 9 (205659_at), score: -0.56 HHLA3HERV-H LTR-associating 3 (220387_s_at), score: -0.65 HOXA7homeobox A7 (206848_at), score: 0.58 HSPB3heat shock 27kDa protein 3 (206375_s_at), score: -0.77 ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein (208937_s_at), score: 0.76 IFFO1intermediate filament family orphan 1 (36030_at), score: -0.64 IGF1insulin-like growth factor 1 (somatomedin C) (209541_at), score: 0.79 IL27RAinterleukin 27 receptor, alpha (205926_at), score: -0.79 ITGA7integrin, alpha 7 (216331_at), score: -0.72 ITGB8integrin, beta 8 (211488_s_at), score: 0.55 ITIH5inter-alpha (globulin) inhibitor H5 (219064_at), score: 0.76 KCNK1potassium channel, subfamily K, member 1 (204679_at), score: 0.57 KCTD15potassium channel tetramerisation domain containing 15 (218553_s_at), score: 0.61 KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (205051_s_at), score: -0.71 KLF5Kruppel-like factor 5 (intestinal) (209212_s_at), score: -0.81 KRT86keratin 86 (215189_at), score: 0.61 LEPRleptin receptor (209894_at), score: -0.76 LEPREL2leprecan-like 2 (204854_at), score: -0.65 LETMD1LETM1 domain containing 1 (207170_s_at), score: -0.6 LHPPphospholysine phosphohistidine inorganic pyrophosphate phosphatase (218523_at), score: -0.63 LMF1lipase maturation factor 1 (219135_s_at), score: -0.61 LMOD1leiomodin 1 (smooth muscle) (203766_s_at), score: -0.77 LPCAT4lysophosphatidylcholine acyltransferase 4 (40472_at), score: -0.74 LRP5low density lipoprotein receptor-related protein 5 (209468_at), score: -0.61 LRRC32leucine rich repeat containing 32 (203835_at), score: -0.61 LTA4Hleukotriene A4 hydrolase (208771_s_at), score: -0.57 LUZP1leucine zipper protein 1 (221832_s_at), score: -0.68 MATN2matrilin 2 (202350_s_at), score: -0.7 MOSC2MOCO sulphurase C-terminal domain containing 2 (221636_s_at), score: -0.58 MR1major histocompatibility complex, class I-related (207565_s_at), score: -0.72 N4BP2L1NEDD4 binding protein 2-like 1 (213375_s_at), score: -0.57 NBEAneurobeachin (221207_s_at), score: 0.56 NDUFA2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa (213550_s_at), score: -0.61 NLGN1neuroligin 1 (205893_at), score: -0.59 NME3non-metastatic cells 3, protein expressed in (204862_s_at), score: -0.85 NOTCH3Notch homolog 3 (Drosophila) (203238_s_at), score: -0.66 NPTX2neuronal pentraxin II (213479_at), score: 0.57 NRCAMneuronal cell adhesion molecule (204105_s_at), score: 0.89 OBFC1oligonucleotide/oligosaccharide-binding fold containing 1 (219100_at), score: -0.61 OCEL1occludin/ELL domain containing 1 (205441_at), score: -0.68 OLFM1olfactomedin 1 (213131_at), score: 0.61 PALLDpalladin, cytoskeletal associated protein (200906_s_at), score: -0.64 PAPPA2pappalysin 2 (213332_at), score: 0.68 PCYOX1Lprenylcysteine oxidase 1 like (218953_s_at), score: -0.7 PEX6peroxisomal biogenesis factor 6 (204545_at), score: -0.65 PHC3polyhomeotic homolog 3 (Drosophila) (215521_at), score: 0.61 PLGLB2plasminogen-like B2 (205871_at), score: 0.66 PLXND1plexin D1 (38671_at), score: -0.59 POLR2J4polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene (60815_at), score: 0.55 PRELPproline/arginine-rich end leucine-rich repeat protein (204223_at), score: -0.81 PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (209040_s_at), score: -0.63 PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (204279_at), score: -0.75 PVRL3poliovirus receptor-related 3 (213325_at), score: 0.55 PYCARDPYD and CARD domain containing (221666_s_at), score: -0.65 RAGErenal tumor antigen (205130_at), score: -0.59 RALGPS2Ral GEF with PH domain and SH3 binding motif 2 (220338_at), score: 0.71 RNASET2ribonuclease T2 (217983_s_at), score: -0.59 SAMD14sterile alpha motif domain containing 14 (213866_at), score: -0.61 SCG5secretogranin V (7B2 protein) (203889_at), score: -0.58 SEMA3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (35666_at), score: -0.58 SGCGsarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (207302_at), score: 0.56 SLC17A5solute carrier family 17 (anion/sugar transporter), member 5 (221041_s_at), score: -0.61 SLC46A3solute carrier family 46, member 3 (214719_at), score: -0.8 SLC6A9solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (207043_s_at), score: 0.58 SORT1sortilin 1 (212807_s_at), score: -0.64 SOX4SRY (sex determining region Y)-box 4 (201417_at), score: 0.54 SPINT2serine peptidase inhibitor, Kunitz type, 2 (210715_s_at), score: -0.76 SPON1spondin 1, extracellular matrix protein (209436_at), score: 0.96 STAG1stromal antigen 1 (202293_at), score: 0.55 STARD5StAR-related lipid transfer (START) domain containing 5 (213820_s_at), score: -0.86 STAT4signal transducer and activator of transcription 4 (206118_at), score: -0.77 SUPT3Hsuppressor of Ty 3 homolog (S. cerevisiae) (206506_s_at), score: -0.58 SV2Asynaptic vesicle glycoprotein 2A (203069_at), score: -0.61 SYNGR2synaptogyrin 2 (201079_at), score: -0.61 TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (202307_s_at), score: -0.68 TAPBPTAP binding protein (tapasin) (208829_at), score: -0.62 TBX1T-box 1 (211273_s_at), score: -0.62 TCF7L1transcription factor 7-like 1 (T-cell specific, HMG-box) (221016_s_at), score: -0.64 THYN1thymocyte nuclear protein 1 (218491_s_at), score: -0.57 TM4SF1transmembrane 4 L six family member 1 (209386_at), score: -0.57 TM4SF20transmembrane 4 L six family member 20 (220639_at), score: -0.57 TMEM159transmembrane protein 159 (213272_s_at), score: -0.59 TMEM176Btransmembrane protein 176B (220532_s_at), score: 0.6 TMEM187transmembrane protein 187 (204340_at), score: -0.7 TNCtenascin C (201645_at), score: 0.62 TRAPPC6Atrafficking protein particle complex 6A (204985_s_at), score: -0.78 TRPV2transient receptor potential cation channel, subfamily V, member 2 (219282_s_at), score: -0.63 UBA7ubiquitin-like modifier activating enzyme 7 (203281_s_at), score: -0.74 UCP2uncoupling protein 2 (mitochondrial, proton carrier) (208998_at), score: -0.74 VAMP1vesicle-associated membrane protein 1 (synaptobrevin 1) (213326_at), score: -0.84 VCAM1vascular cell adhesion molecule 1 (203868_s_at), score: -0.72 VPS11vacuolar protein sorting 11 homolog (S. cerevisiae) (203292_s_at), score: -0.59 ZMIZ1zinc finger, MIZ-type containing 1 (212124_at), score: 0.6
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| F348_WBS.CEL | 16 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| F223_WBS.CEL | 15 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| H652_WBS.CEL | 17 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| F055_WBS.CEL | 14 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| 10590_WBS.CEL | 2 | 8 | WBS | hgu133plus2 | WBS | WBS 1 |
| E-GEOD-3860-raw-cel-1561690472.cel | 17 | 5 | HGPS | hgu133a | none | GM00038C |
| E-GEOD-3860-raw-cel-1561690256.cel | 6 | 5 | HGPS | hgu133a | none | GMO8398C |
| E-GEOD-3860-raw-cel-1561690392.cel | 14 | 5 | HGPS | hgu133a | none | GMO8398C |
