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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

regulation of protein amino acid phosphorylation

Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.

positive regulation of protein amino acid phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

antigen processing and presentation of peptide antigen via MHC class I

The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

regulation of leukocyte migration

Any process that modulates the frequency, rate, or extent of leukocyte migration.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

protein modification process

The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).

protein amino acid phosphorylation

The process of introducing a phosphate group on to a protein.

phosphorus metabolic process

The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).

phosphate metabolic process

The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.

cell motion

Any process involved in the controlled movement of a cell.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

locomotory behavior

The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

positive regulation of metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

regulation of signal transduction

Any process that modulates the frequency, rate or extent of signal transduction.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

positive regulation of phosphorus metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.

positive regulation of macromolecule metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

cell migration

The orderly movement of cells from one site to another, often during the development of a multicellular organism or multicellular structure.

peptidyl-serine phosphorylation

The posttranslational phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.

peptidyl-amino acid modification

The alteration of an amino acid residue in a peptide.

peptidyl-serine modification

The modification of peptidyl-serine.

regulation of phosphate metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

antigen processing and presentation

The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

positive regulation of cell migration

Any process that activates or increases the frequency, rate or extent of cell migration.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

positive regulation of cellular metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

regulation of protein modification process

Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.

positive regulation of protein modification process

Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.

regulation of cellular protein metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

positive regulation of cellular protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

regulation of peptidyl-serine phosphorylation

Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.

positive regulation of peptidyl-serine phosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

locomotion

Self-propelled movement of a cell or organism from one location to another.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

regulation of phosphorylation

Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.

positive regulation of phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.

biopolymer modification

The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties.

post-translational protein modification

The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

cellular protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.

positive regulation of phosphate metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.

antigen processing and presentation of peptide antigen

The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

leukocyte migration

The movement of leukocytes within or between different tissues and organs of the body.

regulation of phosphorus metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of protein metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.

positive regulation of protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

localization of cell

Any process by which a cell is transported to, and/or maintained in, a specific location.

regulation of macromolecule metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

positive regulation of metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

positive regulation of macromolecule metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of macromolecule metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

positive regulation of cellular metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

regulation of leukocyte migration

Any process that modulates the frequency, rate, or extent of leukocyte migration.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

positive regulation of cellular metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

cell motion

Any process involved in the controlled movement of a cell.

positive regulation of cellular metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

positive regulation of macromolecule metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

positive regulation of phosphorus metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.

regulation of phosphorus metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.

regulation of protein metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.

positive regulation of protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

regulation of signal transduction

Any process that modulates the frequency, rate or extent of signal transduction.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

regulation of leukocyte migration

Any process that modulates the frequency, rate, or extent of leukocyte migration.

positive regulation of cell migration

Any process that activates or increases the frequency, rate or extent of cell migration.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

positive regulation of cell migration

Any process that activates or increases the frequency, rate or extent of cell migration.

leukocyte migration

The movement of leukocytes within or between different tissues and organs of the body.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

positive regulation of cellular protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

positive regulation of cellular protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

positive regulation of phosphorus metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.

regulation of cellular protein metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

positive regulation of protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.

cellular protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.

regulation of phosphate metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.

positive regulation of phosphate metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.

protein modification process

The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).

regulation of cellular protein metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

positive regulation of cellular protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

positive regulation of protein modification process

Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.

positive regulation of phosphate metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.

regulation of protein modification process

Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.

positive regulation of protein modification process

Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.

regulation of phosphorylation

Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.

positive regulation of phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.

positive regulation of protein amino acid phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.

positive regulation of protein amino acid phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.

regulation of protein amino acid phosphorylation

Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.

positive regulation of phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.

protein amino acid phosphorylation

The process of introducing a phosphate group on to a protein.

regulation of protein amino acid phosphorylation

Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.

positive regulation of protein amino acid phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.

positive regulation of peptidyl-serine phosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.

peptidyl-serine phosphorylation

The posttranslational phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.

regulation of peptidyl-serine phosphorylation

Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.

positive regulation of peptidyl-serine phosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

MHC class I protein complex

A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

MHC class I receptor activity

Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

Id	Pvalue	ExpCount	Count	Size	Term
GO:0002376	3.551e-11	11	41 C1R, C1S, CBLB, CCL2, CCRL1, CD55, CD97, CLEC7A, CSF1, CXCL1, CXCL2, CXCL3, DPP4, GCH1, GEM, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, ICAM1, IL11, IL1RAP, IL1RL1, IL6, IL8, JARID2, LIF, LY96, NFIL3, NFKB1, NP, OSTM1, RUNX1, SECTM1, SHB, SOD2, SOX4, TRIM22, VEGFA	475	immune system process
GO:0009611	1.602e-10	5.351	28 BMP2, C1R, C1S, CCL2, CD55, CD97, CLEC7A, CXCL1, CXCL2, CXCL3, F10, F3, FGF7, GAP43, HBEGF, HMOX1, IL1RAP, IL6, IL8, JMJD3, LY96, NFKB1, NINJ1, PDGFA, PPARD, SOD2, THBD, TPST1	231	response to wounding
GO:0009605	1.065e-09	8.57	34 BMP2, C1R, C1S, CCL2, CCRL1, CD55, CD97, CLEC7A, CXCL1, CXCL2, CXCL3, EGR2, F10, F3, FGF2, FGF7, GAP43, HBEGF, HMOX1, IL1RAP, IL6, IL8, JMJD3, LY96, NFKB1, NINJ1, NPC1, NR4A3, PDGFA, PPARD, SOD2, THBD, TPST1, VEGFA	370	response to external stimulus
GO:0006955	9.399e-09	6.833	29 C1R, C1S, CBLB, CCL2, CCRL1, CD55, CD97, CLEC7A, CXCL1, CXCL2, CXCL3, GCH1, GEM, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, ICAM1, IL1RAP, IL1RL1, IL6, IL8, LIF, LY96, NFIL3, SECTM1, TRIM22	295	immune response
GO:0032501	1.705e-07	38.17	74 ACSL1, ADRA2A, ANGPTL4, ANO1, AQP1, BMP2, CCL2, COL15A1, CREG1, CSF1, CST3, CXCL1, DCN, DES, DKK2, EGR2, EGR3, F10, F3, FGF2, FGF7, FNDC3A, FOSB, GAA, GAP43, GCH1, GPNMB, HBEGF, HK2, HMOX1, HOXC10, HSPB7, HTR2A, IL11, IL6, IL8, ITPR3, JARID2, LIF, MAN2B1, MEOX1, NFKB1, NINJ1, NKX3-1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PDGFA, PPARD, PPL, RPS4Y1, RUNX1, SECTM1, SEMA5A, SHB, SLC19A2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, TBX3, THBD, TNFAIP2, TNFRSF11B, TNS3, TNXB, TPP1, USP22, VEGFA, ZMYM6	1648	multicellular organismal process
GO:0050896	1.439e-06	31.27	63 ADRA2A, ANGPTL4, BMP2, C1R, C1S, CBLB, CCL2, CCRL1, CD55, CD97, CLEC7A, CST3, CXCL1, CXCL2, CXCL3, DPP4, EGR2, F10, F3, FGF2, FGF7, FOSB, GAA, GAP43, GCH1, GEM, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, HSPB7, HTR2A, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, IL8, JMJD3, LIF, LY96, MAN2B1, NFIL3, NFKB1, NINJ1, NLGN4X, NPC1, NR3C1, NR4A3, PDGFA, PPARD, SECTM1, SOCS2, SOD2, SOD3, THBD, TPST1, TRIB1, TRIM22, VEGFA	1350	response to stimulus
GO:0006954	3.217e-06	3.544	18 BMP2, C1R, C1S, CCL2, CD55, CD97, CLEC7A, CXCL1, CXCL2, CXCL3, HMOX1, IL1RAP, IL6, IL8, JMJD3, LY96, NFKB1, TPST1	153	inflammatory response
GO:0007275	3.680e-06	29.74	60 ANGPTL4, ANO1, BMP2, CCL2, COL15A1, CREG1, CSF1, CST3, CXCL1, DCN, DKK2, EGR2, EGR3, FGF2, FGF7, FNDC3A, FOSB, GAA, GAP43, GPNMB, HBEGF, HMOX1, HOXC10, IL11, IL6, IL8, JARID2, LIF, MEOX1, NFKB1, NINJ1, NKX3-1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PDGFA, PPARD, PPL, RPS4Y1, RUNX1, SECTM1, SEMA5A, SHB, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, TBX3, THBD, TNFAIP2, TNFRSF11B, TNS3, TPP1, USP22, VEGFA, ZMYM6	1284	multicellular organismal development
GO:0048513	6.335e-06	17.21	42 ANGPTL4, BMP2, CCL2, COL15A1, CSF1, CST3, DCN, EGR2, EGR3, FGF2, FGF7, FNDC3A, GAA, GAP43, GPNMB, HBEGF, HMOX1, IL11, IL6, IL8, JARID2, LIF, NFKB1, NINJ1, NP, NR3C1, NR4A3, OSTM1, PPARD, PPL, RUNX1, SECTM1, SEMA5A, SHB, SOD2, SOX4, SPRY2, TBX3, TNFAIP2, TNFRSF11B, TNS3, VEGFA	743	organ development
GO:0042127	9.894e-06	8.825	28 ADRA2A, BMP2, CCL2, CSF1, CXCL1, FGF2, FGF7, GPNMB, HBEGF, HMOX1, HOXC10, HTR2A, IFITM1, IL11, IL6, IL8, JARID2, LIF, NAMPT, NP, PDGFA, PPAP2A, SOD2, SOX4, TBX3, TNS3, TRIB1, VEGFA	381	regulation of cell proliferation
GO:0007610	1.056e-05	3.845	18 CCL2, CCRL1, CXCL1, CXCL2, CXCL3, EGR2, FGF2, FOSB, GAA, HTR2A, IL6, IL8, MAN2B1, NLGN4X, NR4A3, PDGFA, SOD2, VEGFA	166	behavior
GO:0006952	3.165e-05	6.092	22 BMP2, C1R, C1S, CCL2, CD55, CD97, CLEC7A, CST3, CXCL1, CXCL2, CXCL3, GCH1, HLA-B, HMOX1, IL1RAP, IL1RL1, IL6, IL8, JMJD3, LY96, NFKB1, TPST1	263	defense response
GO:0008284	6.454e-05	4.378	18 ADRA2A, CCL2, CSF1, FGF2, FGF7, HBEGF, HOXC10, HTR2A, IL11, IL6, LIF, NAMPT, NP, PDGFA, SOX4, TBX3, TNS3, VEGFA	189	positive regulation of cell proliferation
GO:0048731	1.992e-04	23.37	47 ANGPTL4, BMP2, CCL2, COL15A1, CSF1, CST3, CXCL1, DCN, EGR2, EGR3, FGF2, FGF7, FNDC3A, GAA, GAP43, GPNMB, HBEGF, HMOX1, HOXC10, IL11, IL6, IL8, JARID2, LIF, NFKB1, NINJ1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PPARD, PPL, RUNX1, SECTM1, SEMA5A, SHB, SOD2, SOX11, SOX4, SPRY2, TBX3, TNFAIP2, TNFRSF11B, TNS3, TPP1, VEGFA	1009	system development
GO:0008283	2.751e-04	13.09	32 ADRA2A, BMP2, CCL2, CREG1, CSF1, CXCL1, FGF2, FGF7, GPNMB, HBEGF, HMOX1, HOXC10, HTR2A, IFITM1, IL11, IL6, IL8, JARID2, LIF, NAMPT, NP, PDGFA, PDGFD, PPAP2A, PPARD, SHB, SOD2, SOX4, TBX3, TNS3, TRIB1, VEGFA	565	cell proliferation
GO:0032502	3.084e-04	44.08	72 ANGPTL4, ANO1, BMP2, CCL2, CDC42SE1, COL15A1, CREG1, CSF1, CST3, CXCL1, DCN, DKK2, EGR2, EGR3, FGF2, FGF7, FNDC3A, FOSB, GAA, GAP43, GNPTAB, GPNMB, HBEGF, HMOX1, HOXC10, HTR2A, HTRA1, IL11, IL6, IL8, JARID2, LIF, MEOX1, MTSS1, NFKB1, NINJ1, NKX3-1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PDGFA, PHLDA1, PPARD, PPL, RPS4Y1, RUNX1, SECTM1, SEMA5A, SERPINB2, SHB, SOCS2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, TBX3, THBD, TM2D1, TNFAIP2, TNFAIP8, TNFRSF11B, TNS3, TP53BP2, TPP1, USP22, VEGFA, WISP2, ZMYM6	1903	developmental process
GO:0007626	5.194e-04	2.34	12 CCL2, CCRL1, CXCL1, CXCL2, CXCL3, FGF2, GAA, IL6, IL8, PDGFA, SOD2, VEGFA	101	locomotory behavior
GO:0006950	5.572e-04	19.87	41 ADRA2A, ANGPTL4, BMP2, C1R, C1S, CCL2, CD55, CD97, CLEC7A, CST3, CXCL1, CXCL2, CXCL3, DPP4, F10, F3, FGF7, GAP43, GCH1, HBEGF, HLA-B, HMOX1, HSPB7, HTR2A, IL1RAP, IL1RL1, IL6, IL8, JMJD3, LY96, NFKB1, NINJ1, NPC1, PDGFA, PPARD, SOD2, SOD3, THBD, TPST1, TRIB1, VEGFA	858	response to stress
GO:0006928	5.583e-04	6.231	20 ADRA2A, CCL2, CD97, CSF1, EGR2, FGF2, GAP43, HBEGF, HMOX1, ICAM1, IL6, IL8, MTSS1, PDGFA, PPAP2A, PPARD, SEMA5A, TNS3, TRIB1, VEGFA	269	cell motion
GO:0051674	5.583e-04	6.231	20 ADRA2A, CCL2, CD97, CSF1, EGR2, FGF2, GAP43, HBEGF, HMOX1, ICAM1, IL6, IL8, MTSS1, PDGFA, PPAP2A, PPARD, SEMA5A, TNS3, TRIB1, VEGFA	269	localization of cell
GO:0006935	5.686e-04	1.598	10 CCL2, CCRL1, CXCL1, CXCL2, CXCL3, FGF2, IL6, IL8, PDGFA, VEGFA	69	chemotaxis
GO:0042330	5.686e-04	1.598	10 CCL2, CCRL1, CXCL1, CXCL2, CXCL3, FGF2, IL6, IL8, PDGFA, VEGFA	69	taxis
GO:0040011	7.433e-04	5.281	18 CCL2, CCRL1, CSF1, CXCL1, CXCL2, CXCL3, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, PDGFA, PPAP2A, PPARD, TNS3, TRIB1, VEGFA	228	locomotion
GO:0048856	7.702e-04	28.56	52 ANGPTL4, BMP2, CCL2, CDC42SE1, COL15A1, CSF1, CST3, CXCL1, DCN, EGR2, EGR3, FGF2, FGF7, FNDC3A, GAA, GAP43, GPNMB, HBEGF, HMOX1, HOXC10, HTRA1, IL11, IL6, IL8, JARID2, LIF, MTSS1, NFKB1, NINJ1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PPARD, PPL, RUNX1, SECTM1, SEMA5A, SHB, SOCS2, SOD2, SOX11, SOX4, SPRY2, TBX3, TNFAIP2, TNFRSF11B, TNS3, TPP1, VEGFA, WISP2	1233	anatomical structure development
GO:0009887	1.325e-03	7.227	21 ANGPTL4, BMP2, CCL2, COL15A1, CST3, DCN, FGF2, GAA, HMOX1, IL6, IL8, JARID2, NR4A3, SEMA5A, SHB, SOD2, SPRY2, TBX3, TNFAIP2, TNFRSF11B, VEGFA	312	organ morphogenesis
GO:0010646	1.518e-03	9.729	25 ASAP2, BMP2, DKK2, ECM1, EGR2, HMOX1, HTR2A, HTRA1, IL11, IL1RL1, IL6, LIF, NPC1, PPARD, RAPGEF2, RGS3, SECTM1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, TRAF3IP2, TRIB1, VEGFA	420	regulation of cell communication
GO:0042060	1.853e-03	1.853	10 F10, F3, GAP43, HBEGF, HMOX1, IL6, NINJ1, PDGFA, PPARD, THBD	80	wound healing
GO:0007154	2.403e-03	45.1	70 ADRA2A, ANGPTL4, ASAP2, BMP2, CBLB, CCL2, CCRL1, CD97, CDC42SE1, CLEC7A, CXCL1, DKK2, ECM1, EGR2, EGR3, FGF2, FGF7, GAP43, GEM, GRN, HBEGF, HMOX1, HTR2A, HTRA1, IFITM1, IL11, IL1RAP, IL1RL1, IL6, IL8, ITPR3, LGR4, LIF, LY96, MFAP4, MTSS1, NAMPT, NFATC1, NFKB1, NPC1, NPTX1, NR3C1, PDGFA, PIK3CD, PMEPA1, PPAP2A, PPARD, RAPGEF2, RCAN2, RGS3, RRAD, SECTM1, SEMA5A, SHB, SOCS2, SOD2, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TBX3, TEX2, TNFRSF11B, TNXB, TP53BP2, TRAF3IP2, TRIB1, VEGFA, WISP2	1947	cell communication
GO:0040012	2.442e-03	1.923	10 CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, PDGFA, TRIB1, VEGFA	83	regulation of locomotion
GO:0030335	3.141e-03	0.9034	7 CSF1, FGF2, HBEGF, ICAM1, IL6, PDGFA, VEGFA	39	positive regulation of cell migration
GO:0048518	3.306e-03	20.11	39 ADRA2A, ANGPTL4, BMP2, C1R, C1S, CCL2, CD55, CSF1, ECM1, EGR2, FGF2, FGF7, HBEGF, HMOX1, HOXC10, HTR2A, ICAM1, IL11, IL6, IL8, LIF, MEOX1, NAMPT, NFKB1, NP, NR4A3, PDGFA, PPARD, RUNX1, SECTM1, SOD2, SOX4, TBX3, TM2D1, TNS3, TP53BP2, TRAF3IP2, USP22, VEGFA	868	positive regulation of biological process
GO:0002474	3.642e-03	0.3938	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	17	antigen processing and presentation of peptide antigen via MHC class I
GO:0002685	3.736e-03	0.2085	4 HMOX1, ICAM1, IL6, VEGFA	9	regulation of leukocyte migration
GO:0016477	4.375e-03	3.961	14 CCL2, CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, PDGFA, PPAP2A, PPARD, TNS3, TRIB1, VEGFA	171	cell migration
GO:0051239	4.997e-03	7.412	20 ANGPTL4, BMP2, CSF1, CST3, DES, EGR2, FGF2, GAA, HBEGF, HMOX1, HSPB7, HTR2A, IL6, LIF, NFKB1, NP, PDGFA, RUNX1, TBX3, TNFRSF11B	320	regulation of multicellular organismal process
GO:0033135	5.234e-03	0.09265	3 IL11, IL6, LIF	4	regulation of peptidyl-serine phosphorylation
GO:0033138	5.234e-03	0.09265	3 IL11, IL6, LIF	4	positive regulation of peptidyl-serine phosphorylation
GO:0030334	5.624e-03	1.737	9 CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, PDGFA, TRIB1, VEGFA	75	regulation of cell migration
GO:0009966	5.633e-03	8.733	22 ASAP2, BMP2, DKK2, ECM1, HMOX1, HTRA1, IL11, IL1RL1, IL6, LIF, PPARD, RAPGEF2, RGS3, SECTM1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, TRAF3IP2, TRIB1, VEGFA	377	regulation of signal transduction
GO:0050900	5.663e-03	0.6949	6 CCL2, HMOX1, ICAM1, IL6, IL8, VEGFA	30	leukocyte migration
GO:0048870	5.966e-03	4.1	14 CCL2, CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, PDGFA, PPAP2A, PPARD, TNS3, TRIB1, VEGFA	177	cell motility
GO:0051272	6.174e-03	1.019	7 CSF1, FGF2, HBEGF, ICAM1, IL6, PDGFA, VEGFA	44	positive regulation of cell motion
GO:0007165	7.948e-03	41.69	64 ADRA2A, ANGPTL4, ASAP2, BMP2, CBLB, CCL2, CCRL1, CD97, CDC42SE1, CLEC7A, CXCL1, DKK2, ECM1, FGF2, FGF7, GAP43, GEM, GRN, HBEGF, HMOX1, HTR2A, HTRA1, IFITM1, IL11, IL1RAP, IL1RL1, IL6, IL8, ITPR3, LGR4, LIF, LY96, MFAP4, MTSS1, NAMPT, NFATC1, NFKB1, NR3C1, PDGFA, PIK3CD, PMEPA1, PPAP2A, PPARD, RAPGEF2, RCAN2, RGS3, RRAD, SECTM1, SHB, SOCS2, SOD2, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TEX2, TNFRSF11B, TNXB, TP53BP2, TRAF3IP2, TRIB1, VEGFA, WISP2	1800	signal transduction
GO:0048002	9.004e-03	0.4864	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	21	antigen processing and presentation of peptide antigen
GO:0007243	1.098e-02	6.717	18 ADRA2A, CCL2, ECM1, FGF2, HMOX1, IL11, IL1RL1, IL6, LIF, LY96, PPARD, RAPGEF2, RGS3, SECTM1, SOCS2, STK38L, TRAF3IP2, TRIB1	290	protein kinase cascade
GO:0048514	1.158e-02	2.872	11 ANGPTL4, COL15A1, CST3, FGF2, HMOX1, IL6, IL8, SEMA5A, SHB, TNFAIP2, VEGFA	124	blood vessel morphogenesis
GO:0048646	1.185e-02	3.382	12 ANGPTL4, COL15A1, EGR2, FGF2, HMOX1, IL6, IL8, NR4A3, SEMA5A, SHB, TNFAIP2, VEGFA	146	anatomical structure formation
GO:0001525	1.193e-02	2.409	10 ANGPTL4, COL15A1, FGF2, HMOX1, IL6, IL8, SEMA5A, SHB, TNFAIP2, VEGFA	104	angiogenesis
GO:0007267	1.218e-02	6.185	17 BMP2, CD97, EGR2, EGR3, FGF2, HTR2A, IL11, IL6, IL8, LIF, NAMPT, NPTX1, PDGFA, SEMA5A, SPRY2, TBX3, WISP2	267	cell-cell signaling
GO:0045597	1.227e-02	1.969	9 BMP2, CSF1, FGF2, IL6, LIF, NFKB1, NP, PPARD, RUNX1	85	positive regulation of cell differentiation
GO:0007155	1.267e-02	8.709	21 AJAP1, CCL2, CD97, COL14A1, COL15A1, CSF1, DPP4, DPT, FNDC3A, GPNMB, ICAM1, IL8, MTSS1, NID1, NINJ1, NLGN4X, PKP2, PPARD, SEMA5A, SVEP1, WISP2	376	cell adhesion
GO:0022610	1.267e-02	8.709	21 AJAP1, CCL2, CD97, COL14A1, COL15A1, CSF1, DPP4, DPT, FNDC3A, GPNMB, ICAM1, IL8, MTSS1, NID1, NINJ1, NLGN4X, PKP2, PPARD, SEMA5A, SVEP1, WISP2	376	biological adhesion
GO:0050905	1.292e-02	0.5328	5 GAA, GCH1, HOXC10, NR4A3, TPP1	23	neuromuscular process
GO:0019216	1.316e-02	0.8339	6 ACSL1, NFKB1, NPC2, NR3C1, PDGFA, PPAP2A	36	regulation of lipid metabolic process
GO:0002682	1.375e-02	3.451	12 C1R, C1S, CD55, CSF1, HMOX1, ICAM1, IL6, LIF, NFKB1, NP, RUNX1, VEGFA	149	regulation of immune system process
GO:0002763	1.408e-02	0.3011	4 CSF1, LIF, NFKB1, RUNX1	13	positive regulation of myeloid leukocyte differentiation
GO:0001775	1.586e-02	3.521	12 CLEC7A, CSF1, DPP4, HMOX1, ICAM1, IL11, IL6, IL8, NP, PDGFA, SHB, SOX4	152	cell activation
GO:0051270	1.710e-02	2.085	9 CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, PDGFA, TRIB1, VEGFA	90	regulation of cell motion
GO:0009888	1.737e-02	3.567	12 BMP2, CST3, FGF7, GAA, GAP43, GPNMB, NINJ1, NR4A3, PPARD, PPL, SECTM1, TBX3	154	tissue development
GO:0009653	1.824e-02	16.05	31 ANGPTL4, BMP2, CCL2, CDC42SE1, COL15A1, CST3, DCN, EGR2, FGF2, GAA, GAP43, HMOX1, HOXC10, HTRA1, IL6, IL8, JARID2, MTSS1, NINJ1, NR4A3, PPL, SEMA5A, SHB, SOCS2, SOD2, SPRY2, TBX3, TNFAIP2, TNFRSF11B, VEGFA, WISP2	693	anatomical structure morphogenesis
GO:0065007	1.862e-02	87.28	110 ACSL1, ADRA2A, ANGPTL4, ASAP2, BMP2, C1R, C1S, CBLB, CCL2, CCRL1, CD55, CD97, CDC42SE1, CLEC7A, CREG1, CSF1, CST3, CXCL1, DES, DKK2, DPP4, ECM1, EGR2, EGR3, F10, F3, FGF2, FGF7, FOSB, GAA, GAP43, GCH1, GEM, GPNMB, GRN, HBEGF, HMOX1, HOXC10, HSD17B11, HSPB7, HTR2A, HTRA1, ICAM1, IFITM1, IL11, IL1RAP, IL1RL1, IL6, IL8, ITPR3, JARID2, JMJD3, KHDRBS3, LGR4, LIF, LMCD1, LY96, MEIS3P1, MEOX1, MFAP4, MTSS1, NAMPT, NFATC1, NFIL3, NFKB1, NKX3-1, NP, NPC1, NPC2, NR3C1, NR4A3, PDGFA, PDGFD, PIK3CD, PMEPA1, PPAP2A, PPARD, RAPGEF2, RCAN2, RGS3, RRAD, RUNX1, SECTM1, SERPINB2, SHB, SOCS2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TBX3, TEX2, THBD, TM2D1, TNFAIP8, TNFRSF11B, TNS3, TNXB, TP53BP2, TPP1, TRAF3IP2, TRIB1, TRIM22, USP22, VEGFA, WISP2, ZBTB20	3768	biological regulation
GO:0019882	2.083e-02	0.9265	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, ICAM1	40	antigen processing and presentation
GO:0001568	2.256e-02	3.173	11 ANGPTL4, COL15A1, CST3, FGF2, HMOX1, IL6, IL8, SEMA5A, SHB, TNFAIP2, VEGFA	137	blood vessel development
GO:0045321	2.256e-02	3.173	11 CLEC7A, CSF1, DPP4, HMOX1, ICAM1, IL11, IL6, IL8, NP, SHB, SOX4	137	leukocyte activation
GO:0048523	2.263e-02	20.13	36 ANGPTL4, BMP2, CCL2, CST3, CXCL1, DKK2, FGF2, FOSB, GPNMB, HMOX1, HTR2A, HTRA1, IFITM1, IL11, IL1RL1, IL6, IL8, JARID2, JMJD3, LIF, LMCD1, MTSS1, NFKB1, NPC1, PDGFA, PPAP2A, RGS3, SERPINB2, SOCS2, SOD2, SOX4, TBX3, TNFAIP8, TP53BP2, TRIB1, VEGFA	869	negative regulation of cellular process
GO:0048522	2.446e-02	18.69	34 ADRA2A, BMP2, CCL2, CSF1, ECM1, EGR2, FGF2, FGF7, HBEGF, HMOX1, HOXC10, HTR2A, ICAM1, IL11, IL6, LIF, MEOX1, NAMPT, NFKB1, NP, NR4A3, PDGFA, PPARD, RUNX1, SECTM1, SOD2, SOX4, TBX3, TM2D1, TNS3, TP53BP2, TRAF3IP2, USP22, VEGFA	807	positive regulation of cellular process
GO:0001944	2.477e-02	3.22	11 ANGPTL4, COL15A1, CST3, FGF2, HMOX1, IL6, IL8, SEMA5A, SHB, TNFAIP2, VEGFA	139	vasculature development
GO:0042221	2.516e-02	9.983	22 CCL2, CCRL1, CLEC7A, CXCL1, CXCL2, CXCL3, EGR2, FGF2, GCH1, HMOX1, HSPB7, HTR2A, IL6, IL8, NPC1, NR3C1, PDGFA, SOCS2, SOD2, THBD, TRIB1, VEGFA	431	response to chemical stimulus
GO:0048519	3.019e-02	21.33	37 ANGPTL4, BMP2, CCL2, CST3, CXCL1, DKK2, FGF2, FOSB, GPNMB, HMOX1, HTR2A, HTRA1, IFITM1, IL11, IL1RL1, IL6, IL8, JARID2, JMJD3, LIF, LMCD1, MTSS1, NFKB1, NPC1, PDGFA, PPAP2A, RGS3, SERPINB2, SOCS2, SOD2, SOX4, TBX3, TNFAIP8, TNFRSF11B, TP53BP2, TRIB1, VEGFA	921	negative regulation of biological process
GO:0002237	3.239e-02	0.3938	4 GCH1, IL6, THBD, TRIB1	17	response to molecule of bacterial origin
GO:0010713	3.285e-02	0.04633	2 CST3, IL6	2	negative regulation of collagen metabolic process
GO:0044252	3.285e-02	0.04633	2 CST3, IL6	2	negative regulation of multicellular organismal metabolic process
GO:0048583	3.297e-02	2.849	10 C1R, C1S, CD55, HMOX1, ICAM1, IL6, IL8, NPC1, PDGFA, VEGFA	123	regulation of response to stimulus
GO:0006959	3.394e-02	0.6949	5 C1R, C1S, CCL2, CD55, IL6	30	humoral immune response
GO:0007166	3.567e-02	16.17	30 ADRA2A, BMP2, CBLB, CCL2, CCRL1, CD97, CXCL1, DKK2, FGF2, FGF7, GAP43, GEM, HBEGF, HTR2A, HTRA1, IFITM1, IL6, IL8, ITPR3, LGR4, LIF, LY96, MTSS1, PDGFA, PPAP2A, RGS3, SOCS2, SOX4, TRIB1, VEGFA	698	cell surface receptor linked signal transduction
GO:0050789	3.611e-02	82.79	104 ACSL1, ADRA2A, ANGPTL4, ASAP2, BMP2, C1R, C1S, CBLB, CCL2, CCRL1, CD55, CD97, CDC42SE1, CLEC7A, CREG1, CSF1, CST3, CXCL1, DES, DKK2, DPP4, ECM1, EGR2, EGR3, FGF2, FGF7, FOSB, GAA, GAP43, GEM, GPNMB, GRN, HBEGF, HMOX1, HOXC10, HSPB7, HTR2A, HTRA1, ICAM1, IFITM1, IL11, IL1RAP, IL1RL1, IL6, IL8, ITPR3, JARID2, JMJD3, KHDRBS3, LGR4, LIF, LMCD1, LY96, MEIS3P1, MEOX1, MFAP4, MTSS1, NAMPT, NFATC1, NFIL3, NFKB1, NKX3-1, NP, NPC1, NPC2, NR3C1, NR4A3, PDGFA, PDGFD, PIK3CD, PMEPA1, PPAP2A, PPARD, RAPGEF2, RCAN2, RGS3, RRAD, RUNX1, SECTM1, SERPINB2, SHB, SOCS2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TBX3, TEX2, TM2D1, TNFAIP8, TNFRSF11B, TNS3, TNXB, TP53BP2, TRAF3IP2, TRIB1, TRIM22, USP22, VEGFA, WISP2, ZBTB20	3574	regulation of biological process
GO:0002687	3.683e-02	0.1853	3 ICAM1, IL6, VEGFA	8	positive regulation of leukocyte migration
GO:0045087	4.003e-02	1.506	7 C1R, C1S, CD55, CLEC7A, GCH1, IL1RAP, IL1RL1	65	innate immune response
GO:0010648	4.541e-02	2.015	8 DKK2, HTR2A, HTRA1, IL1RL1, NPC1, RGS3, SOCS2, TRIB1	87	negative regulation of cell communication
GO:0043405	4.781e-02	1.575	7 ADRA2A, FGF2, HTR2A, RGS3, SPRY2, SPRY4, TRIB1	68	regulation of MAP kinase activity

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005576	5.300e-17	15.72	58 ANGPTL4, APOD, BMP2, C1R, C1S, CCL2, CD97, COL14A1, COL15A1, CREG1, CSF1, CST3, CTSL1, CXCL1, CXCL2, CXCL3, DCN, DKK2, DPP4, DPT, ECM1, F10, FGF2, FGF7, GRN, HBEGF, HLA-C, HMOX1, HSD17B11, HTRA1, ICAM1, IL11, IL1RAP, IL1RL1, IL33, IL6, IL8, ITIH2, LIF, LY96, MFAP4, NID1, NPC2, OLFML2A, PDGFA, PDGFD, PTGDS, SCPEP1, SECTM1, SERPINB2, SOD3, SVEP1, THBD, TNFAIP2, TNFRSF11B, TNXB, VEGFA, WISP2	700	extracellular region
GO:0044421	4.490e-12	8.689	37 ANGPTL4, APOD, BMP2, CCL2, COL14A1, COL15A1, CSF1, CST3, CXCL1, CXCL2, CXCL3, DCN, DKK2, DPT, ECM1, FGF2, GRN, HBEGF, HMOX1, HTRA1, ICAM1, IL11, IL33, IL6, IL8, LIF, MFAP4, NID1, OLFML2A, PDGFA, SECTM1, SOD3, THBD, TNFAIP2, TNFRSF11B, TNXB, VEGFA	387	extracellular region part
GO:0005615	6.376e-10	5.523	27 ANGPTL4, APOD, BMP2, CCL2, CSF1, CST3, CXCL1, CXCL2, CXCL3, DKK2, FGF2, GRN, HBEGF, HMOX1, HTRA1, ICAM1, IL11, IL33, IL6, IL8, LIF, PDGFA, SECTM1, SOD3, THBD, TNFAIP2, VEGFA	246	extracellular space
GO:0042612	6.140e-04	0.3368	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	15	MHC class I protein complex
GO:0042611	3.665e-03	0.4939	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	22	MHC protein complex
GO:0005886	6.264e-03	32.4	52 ADRA2A, AJAP1, AQP1, ASAP2, CADPS2, CCRL1, CD55, CD97, CDC42SE1, CLEC2B, CSF1, DDX3Y, DES, DPP4, F10, F3, GAP43, GEM, GPNMB, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, ITPR3, LGR4, LY96, NLGN4X, NPC1, PKP2, PMEPA1, PPAP2A, PPL, RAPGEF2, RGS3, SECTM1, SHB, SLC19A2, SPRED2, SPRY2, SPRY4, STOM, THBD, TM2D1, TNS3	1443	plasma membrane
GO:0031012	1.029e-02	3.727	12 ANGPTL4, COL14A1, COL15A1, DCN, DPT, ECM1, MFAP4, NID1, OLFML2A, TNFRSF11B, TNXB, VEGFA	166	extracellular matrix
GO:0005578	2.010e-02	3.503	11 ANGPTL4, COL14A1, COL15A1, DCN, DPT, ECM1, MFAP4, NID1, TNFRSF11B, TNXB, VEGFA	156	proteinaceous extracellular matrix
GO:0016020	3.500e-02	71.11	91 ACSL1, ADRA2A, AJAP1, ANO1, AQP1, ASAP2, B4GALT6, CADPS2, CCRL1, CD302, CD55, CD97, CDC42SE1, CLEC2B, CLEC7A, CSF1, CSGALNACT2, DDX3Y, DES, DPP4, F10, F3, FNDC3A, GAP43, GEM, GNPTAB, GPNMB, HBEGF, HK2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, ITPR3, KIAA0247, KIAA1644, LEPROT, LGR4, LHFP, LMBRD1, LRIG1, LRRC15, LY96, MAN1C1, NID1, NINJ1, NLGN4X, NPC1, NR3C1, OLFML2A, OSTM1, PDGFA, PDGFD, PHLDA1, PKP2, PLSCR4, PMEPA1, PPAP2A, PPL, PTGDS, RAPGEF2, RGS3, SECTM1, SEMA5A, SHB, SLC19A2, SLC39A8, SOD2, SPRED2, SPRY2, SPRY4, SQRDL, STOM, SVEP1, TEX2, THBD, TM2D1, TMBIM4, TMEM158, TMEM41B, TNS3, TPST1, VEGFA, WTAP	3167	membrane
GO:0044459	4.148e-02	19.65	33 ADRA2A, AJAP1, AQP1, CADPS2, CCRL1, CD55, CD97, CLEC2B, DPP4, GAP43, GPNMB, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, ICAM1, IL1RAP, IL1RL1, IL6, ITPR3, NLGN4X, NPC1, PKP2, PPAP2A, PPL, RAPGEF2, STOM, THBD, TM2D1, TNS3	875	plasma membrane part

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005125	1.369e-07	1.605	15 BMP2, CCL2, CSF1, CXCL1, CXCL2, GRN, IL11, IL33, IL6, IL8, LIF, NAMPT, SECTM1, TNFRSF11B, VEGFA	73	cytokine activity
GO:0008083	6.037e-05	2.067	13 BMP2, CSF1, CXCL1, FGF2, FGF7, GRN, HBEGF, IL11, IL6, LIF, PDGFA, PDGFD, VEGFA	94	growth factor activity
GO:0005102	9.870e-05	8.971	27 ANGPTL4, BMP2, CCL2, CLEC7A, CSF1, CXCL1, CXCL2, FGF2, FGF7, GPNMB, GRN, HBEGF, ICAM1, IL11, IL33, IL6, IL8, LIF, MFAP4, MTSS1, NAMPT, PDGFA, PDGFD, SECTM1, SOCS2, TNFRSF11B, VEGFA	408	receptor binding
GO:0032393	2.061e-04	0.1979	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	9	MHC class I receptor activity
GO:0004871	3.288e-03	17.55	36 ADRA2A, CBLB, CCL2, CCRL1, CD97, CLEC7A, ECM1, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, HTR2A, ICAM1, IFITM1, IL1RAP, IL1RL1, ITPR3, LGR4, LY96, NPC1, NR3C1, NR4A3, PPARD, RAPGEF2, RGS3, SECTM1, SEMA5A, SHB, SOCS2, THBD, TM2D1, TNFRSF11B, TP53BP2	798	signal transducer activity
GO:0060089	3.288e-03	17.55	36 ADRA2A, CBLB, CCL2, CCRL1, CD97, CLEC7A, ECM1, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, HTR2A, ICAM1, IFITM1, IL1RAP, IL1RL1, ITPR3, LGR4, LY96, NPC1, NR3C1, NR4A3, PPARD, RAPGEF2, RGS3, SECTM1, SEMA5A, SHB, SOCS2, THBD, TM2D1, TNFRSF11B, TP53BP2	798	molecular transducer activity
GO:0008236	1.114e-02	1.451	8 C1R, C1S, DPP4, F10, HTRA1, SCPEP1, SERPINB2, TPP1	66	serine-type peptidase activity
GO:0017171	1.114e-02	1.451	8 C1R, C1S, DPP4, F10, HTRA1, SCPEP1, SERPINB2, TPP1	66	serine hydrolase activity
GO:0004252	1.889e-02	1.209	7 C1R, C1S, DPP4, F10, HTRA1, SERPINB2, TPP1	55	serine-type endopeptidase activity
GO:0004872	2.288e-02	11.72	25 ADRA2A, CCRL1, CD97, CLEC7A, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, ICAM1, IL1RAP, IL1RL1, ITPR3, LGR4, LY96, NPC1, NR3C1, NR4A3, PPARD, SEMA5A, THBD, TM2D1, TNFRSF11B	533	receptor activity
GO:0008009	2.431e-02	0.3298	4 CCL2, CXCL1, CXCL2, IL8	15	chemokine activity
GO:0042379	2.431e-02	0.3298	4 CCL2, CXCL1, CXCL2, IL8	15	chemokine receptor binding
GO:0030246	4.499e-02	2.902	10 CD302, CLEC2B, CLEC7A, FGF2, GAA, GPNMB, HBEGF, MAN2B1, SOD3, VEGFA	132	carbohydrate binding

Id	Pvalue	ExpCount	Count	Size	Term
04060	5.727e-04	3.357	14 BMP2, CCL2, CSF1, CXCL1, CXCL2, CXCL3, IL11, IL1RAP, IL6, IL8, LIF, PDGFA, TNFRSF11B, VEGFA	122	Cytokine-cytokine receptor interaction
05332	1.845e-03	0.5778	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, IL6	21	Graft-versus-host disease
05330	1.625e-02	0.5778	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	21	Allograft rejection
05320	1.938e-02	0.6053	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	22	Autoimmune thyroid disease
04610	1.965e-02	0.9354	6 C1R, C1S, CD55, F10, F3, THBD	34	Complement and coagulation cascades
04630	3.473e-02	2.421	9 CBLB, IL11, IL6, LIF, PIK3CD, SOCS2, SPRED2, SPRY2, SPRY4	88	Jak-STAT signaling pathway
04940	3.605e-02	0.7153	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	26	Type I diabetes mellitus

No enriched terms

No enriched terms

Entrez genes

ACSL1acyl-CoA synthetase long-chain family member 1 (201963_at), score: 0.24 ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide (209612_s_at), score: 0.38 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: 0.43 AJAP1adherens junctions associated protein 1 (206460_at), score: 0.23 AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (209160_at), score: 0.3 ANGPTL4angiopoietin-like 4 (221009_s_at), score: 0.37 ANO1anoctamin 1, calcium activated chloride channel (218804_at), score: 0.23 APODapolipoprotein D (201525_at), score: 0.38 AQP1aquaporin 1 (Colton blood group) (209047_at), score: 0.24 ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (206414_s_at), score: 0.33 B4GALT6UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 (206233_at), score: -0.66 BMP2bone morphogenetic protein 2 (205289_at), score: 0.28 C1Rcomplement component 1, r subcomponent (212067_s_at), score: 0.41 C1Scomplement component 1, s subcomponent (208747_s_at), score: 0.3 CADPS2Ca++-dependent secretion activator 2 (219572_at), score: 0.23 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (209682_at), score: 0.27 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: 0.33 CCRL1chemokine (C-C motif) receptor-like 1 (220351_at), score: 0.49 CD302CD302 molecule (203799_at), score: 0.37 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: 0.23 CD97CD97 molecule (202910_s_at), score: 0.23 CDC42SE1CDC42 small effector 1 (218157_x_at), score: 0.32 CLEC2BC-type lectin domain family 2, member B (209732_at), score: 0.37 CLEC7AC-type lectin domain family 7, member A (221698_s_at), score: -0.66 COL14A1collagen, type XIV, alpha 1 (212865_s_at), score: 0.37 COL15A1collagen, type XV, alpha 1 (203477_at), score: 0.49 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: 0.47 CSF1colony stimulating factor 1 (macrophage) (209716_at), score: 0.34 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: 0.28 CST3cystatin C (201360_at), score: 0.28 CTSL1cathepsin L1 (202087_s_at), score: 0.26 CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (204470_at), score: 0.24 CXCL2chemokine (C-X-C motif) ligand 2 (209774_x_at), score: 0.22 CXCL3chemokine (C-X-C motif) ligand 3 (207850_at), score: 0.32 DCNdecorin (211896_s_at), score: 0.3 DDX3YDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (205000_at), score: 0.26 DESdesmin (202222_s_at), score: -1 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: 0.58 DPP4dipeptidyl-peptidase 4 (211478_s_at), score: 0.41 DPTdermatopontin (213068_at), score: 0.3 DUSP14dual specificity phosphatase 14 (203367_at), score: 0.23 ECM1extracellular matrix protein 1 (209365_s_at), score: 0.38 EGR2early growth response 2 (Krox-20 homolog, Drosophila) (205249_at), score: 0.24 EGR3early growth response 3 (206115_at), score: 0.33 F10coagulation factor X (205620_at), score: 0.3 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: 0.39 FGF2fibroblast growth factor 2 (basic) (204421_s_at), score: 0.25 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: 0.37 FNDC3Afibronectin type III domain containing 3A (202304_at), score: 0.28 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: 0.38 GAAglucosidase, alpha; acid (202812_at), score: 0.27 GAP43growth associated protein 43 (204471_at), score: -0.8 GCH1GTP cyclohydrolase 1 (204224_s_at), score: 0.23 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: 0.27 GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (212959_s_at), score: 0.23 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: 0.69 GRNgranulin (211284_s_at), score: 0.33 HBEGFheparin-binding EGF-like growth factor (203821_at), score: 0.32 HK2hexokinase 2 (202934_at), score: 0.45 HLA-Amajor histocompatibility complex, class I, A (217436_x_at), score: 0.26 HLA-Bmajor histocompatibility complex, class I, B (211911_x_at), score: 0.3 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: 0.38 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: 0.4 HLA-Fmajor histocompatibility complex, class I, F (204806_x_at), score: 0.32 HMGN1high-mobility group nucleosome binding domain 1 (200944_s_at), score: -0.68 HMOX1heme oxygenase (decycling) 1 (203665_at), score: 0.35 HOXC10homeobox C10 (218959_at), score: 0.31 HPCAL1hippocalcin-like 1 (205462_s_at), score: 0.33 HSD17B11hydroxysteroid (17-beta) dehydrogenase 11 (217989_at), score: 0.22 HSPB7heat shock 27kDa protein family, member 7 (cardiovascular) (218934_s_at), score: 0.37 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: 0.29 HTRA1HtrA serine peptidase 1 (201185_at), score: 0.25 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: 0.26 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: 0.29 IFITM1interferon induced transmembrane protein 1 (9-27) (214022_s_at), score: 0.3 IL11interleukin 11 (206924_at), score: 0.22 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: 0.32 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: 0.61 IL33interleukin 33 (209821_at), score: 0.24 IL6interleukin 6 (interferon, beta 2) (205207_at), score: 0.53 IL8interleukin 8 (202859_x_at), score: 0.37 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: -0.66 ITPR3inositol 1,4,5-triphosphate receptor, type 3 (201189_s_at), score: 0.28 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: 0.29 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: 0.38 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: 0.41 KHDRBS3KH domain containing, RNA binding, signal transduction associated 3 (209781_s_at), score: 0.3 KIAA0247KIAA0247 (202181_at), score: 0.23 KIAA1644KIAA1644 (52837_at), score: 0.36 KLHL21kelch-like 21 (Drosophila) (203068_at), score: 0.25 LEPROTleptin receptor overlapping transcript (202378_s_at), score: 0.24 LGR4leucine-rich repeat-containing G protein-coupled receptor 4 (218326_s_at), score: -0.66 LHFPlipoma HMGIC fusion partner (218656_s_at), score: 0.43 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: 0.24 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: 0.36 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: 0.34 LOC286434hypothetical protein LOC286434 (222196_at), score: -0.67 LRIG1leucine-rich repeats and immunoglobulin-like domains 1 (211596_s_at), score: 0.25 LRRC15leucine rich repeat containing 15 (213909_at), score: 0.28 LY96lymphocyte antigen 96 (206584_at), score: 0.36 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.38 MAN2B1mannosidase, alpha, class 2B, member 1 (209166_s_at), score: 0.31 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: 0.26 MEOX1mesenchyme homeobox 1 (205619_s_at), score: -0.68 MFAP4microfibrillar-associated protein 4 (212713_at), score: 0.33 MTSS1metastasis suppressor 1 (203037_s_at), score: 0.31 MYO1Dmyosin ID (212338_at), score: 0.46 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: 0.43 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: 0.38 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: 0.37 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: 0.45 NID1nidogen 1 (202008_s_at), score: 0.25 NINJ1ninjurin 1 (203045_at), score: 0.27 NKX3-1NK3 homeobox 1 (209706_at), score: 0.22 NLGN4Xneuroligin 4, X-linked (221933_at), score: -0.75 NPnucleoside phosphorylase (201695_s_at), score: 0.22 NPC1Niemann-Pick disease, type C1 (202679_at), score: 0.29 NPC2Niemann-Pick disease, type C2 (200701_at), score: 0.44 NPTX1neuronal pentraxin I (204684_at), score: 0.28 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: 0.27 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: 0.45 NT5DC25'-nucleotidase domain containing 2 (218051_s_at), score: -0.67 OLFML2Aolfactomedin-like 2A (213075_at), score: 0.28 OSTM1osteopetrosis associated transmembrane protein 1 (218196_at), score: 0.24 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: 0.26 PDGFDplatelet derived growth factor D (219304_s_at), score: 0.33 PHLDA1pleckstrin homology-like domain, family A, member 1 (217997_at), score: 0.22 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: 0.3 PKP2plakophilin 2 (207717_s_at), score: 0.23 PLSCR4phospholipid scramblase 4 (218901_at), score: 0.22 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: 0.45 PPAP2Aphosphatidic acid phosphatase type 2A (209147_s_at), score: 0.37 PPARDperoxisome proliferator-activated receptor delta (37152_at), score: 0.42 PPLperiplakin (203407_at), score: 0.36 PSG4pregnancy specific beta-1-glycoprotein 4 (208191_x_at), score: 0.26 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: 0.28 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: 0.32 RCAN2regulator of calcineurin 2 (203498_at), score: 0.43 RCL1RNA terminal phosphate cyclase-like 1 (218544_s_at), score: 0.23 RGS3regulator of G-protein signaling 3 (203823_at), score: 0.4 RPS4Y1ribosomal protein S4, Y-linked 1 (201909_at), score: 0.33 RRADRas-related associated with diabetes (204803_s_at), score: 0.53 RUNX1runt-related transcription factor 1 (209360_s_at), score: 0.26 SAT1spermidine/spermine N1-acetyltransferase 1 (213988_s_at), score: 0.24 SCPEP1serine carboxypeptidase 1 (218217_at), score: 0.25 SECTM1secreted and transmembrane 1 (213716_s_at), score: 0.32 SEMA5Asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (205405_at), score: 0.22 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: 0.3 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: 0.3 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: 0.3 SLC39A8solute carrier family 39 (zinc transporter), member 8 (209267_s_at), score: 0.32 SMOXspermine oxidase (210357_s_at), score: 0.24 SOCS2suppressor of cytokine signaling 2 (203373_at), score: 0.23 SOD2superoxide dismutase 2, mitochondrial (221477_s_at), score: 0.28 SOD3superoxide dismutase 3, extracellular (205236_x_at), score: 0.39 SOX11SRY (sex determining region Y)-box 11 (204914_s_at), score: -0.73 SOX4SRY (sex determining region Y)-box 4 (201417_at), score: 0.23 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: 0.28 SPRY2sprouty homolog 2 (Drosophila) (204011_at), score: 0.27 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: 0.28 SQRDLsulfide quinone reductase-like (yeast) (217995_at), score: 0.22 STK38Lserine/threonine kinase 38 like (212572_at), score: 0.28 STOMstomatin (201060_x_at), score: 0.25 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: 0.37 TBX3T-box 3 (219682_s_at), score: 0.32 TEX2testis expressed 2 (218099_at), score: 0.27 THBDthrombomodulin (203887_s_at), score: 0.39 TIPARPTCDD-inducible poly(ADP-ribose) polymerase (212665_at), score: 0.22 TM2D1TM2 domain containing 1 (211703_s_at), score: 0.35 TMBIM4transmembrane BAX inhibitor motif containing 4 (219206_x_at), score: 0.22 TMEM158transmembrane protein 158 (213338_at), score: 0.26 TMEM41Btransmembrane protein 41B (212623_at), score: 0.42 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: 0.43 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (210260_s_at), score: 0.26 TNFRSF11Btumor necrosis factor receptor superfamily, member 11b (204933_s_at), score: 0.39 TNS3tensin 3 (217853_at), score: 0.28 TNXBtenascin XB (216333_x_at), score: 0.3 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: 0.28 TPP1tripeptidyl peptidase I (200742_s_at), score: 0.41 TPST1tyrosylprotein sulfotransferase 1 (204140_at), score: 0.28 TRAF3IP2TRAF3 interacting protein 2 (215411_s_at), score: 0.27 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: 0.32 TRIM22tripartite motif-containing 22 (213293_s_at), score: 0.29 USP22ubiquitin specific peptidase 22 (200083_at), score: -0.67 VEGFAvascular endothelial growth factor A (211527_x_at), score: 0.3 WISP2WNT1 inducible signaling pathway protein 2 (205792_at), score: 0.48 WTAPWilms tumor 1 associated protein (210285_x_at), score: 0.39 ZBTB20zinc finger and BTB domain containing 20 (205383_s_at), score: 0.23 ZMYM6zinc finger, MYM-type 6 (219924_s_at), score: 0.22

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
1Twin.CEL	1	2	DS-twin	hgu133plus2	Down	DS-twin 1
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
5CTwin.CEL	5	2	DS-twin	hgu133plus2	Down	DS-twin 5
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
t21c 08-03.CEL	6	1	DS-CC	hgu133a	Down	DS-CC 6
t21b 08-03.CEL	5	1	DS-CC	hgu133a	Down	DS-CC 5
t21d 08-03.CEL	7	1	DS-CC	hgu133a	Down	DS-CC 7
ctrl b 08-03.CEL	2	1	DS-CC	hgu133a	none	DS-CC 2