Under-expression is coded with green,
over-expression with red color.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
cellular alcohol metabolic process
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.
cellular amino acid and derivative metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.
amino acid derivative metabolic process
The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
biogenic amine metabolic process
The chemical reactions and pathways involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
catecholamine metabolic process
The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
cellular aromatic compound metabolic process
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
phenol metabolic process
The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. The largest single use of phenol is in the production of plastics, but it is also used in the synthesis of caprolactam, a precursor for nylon 6 and other man-made fibers.
cellular nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
cellular nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
cellular amino acid and derivative metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.
phenol metabolic process
The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. The largest single use of phenol is in the production of plastics, but it is also used in the synthesis of caprolactam, a precursor for nylon 6 and other man-made fibers.
biogenic amine metabolic process
The chemical reactions and pathways involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
catecholamine metabolic process
The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
aldo-keto reductase activity
Catalysis of the NADPH-dependent reduction of carbonyl compounds.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
oxidoreductase activity, acting on CH-OH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
oxidoreductase activity, acting on the CH-CH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.
all
This term is the most general term possible
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 00980 | 1.577e-02 | 0.8822 | 6 | 37 | Metabolism of xenobiotics by cytochrome P450 |
ABCG2ATP-binding cassette, sub-family G (WHITE), member 2 (209735_at), score: 0.53 ACSL5acyl-CoA synthetase long-chain family member 5 (218322_s_at), score: 0.5 AEBP1AE binding protein 1 (201792_at), score: -0.57 AHI1Abelson helper integration site 1 (221569_at), score: -0.51 AKAP12A kinase (PRKA) anchor protein 12 (210517_s_at), score: -0.54 AKAP2A kinase (PRKA) anchor protein 2 (202759_s_at), score: -0.59 AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase) (206561_s_at), score: 0.84 AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (204151_x_at), score: 0.54 AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) (209699_x_at), score: 0.57 AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (209160_at), score: 0.56 ALDH1A1aldehyde dehydrogenase 1 family, member A1 (212224_at), score: -0.53 ALDH3A1aldehyde dehydrogenase 3 family, memberA1 (205623_at), score: 0.62 ALDH3A2aldehyde dehydrogenase 3 family, member A2 (202053_s_at), score: 0.55 APH1Aanterior pharynx defective 1 homolog A (C. elegans) (218389_s_at), score: 0.5 ARHGAP5Rho GTPase activating protein 5 (217936_at), score: -0.53 ARMCX1armadillo repeat containing, X-linked 1 (218694_at), score: -0.63 ASB9ankyrin repeat and SOCS box-containing 9 (205673_s_at), score: 0.57 ATP1A1ATPase, Na+/K+ transporting, alpha 1 polypeptide (220948_s_at), score: 0.54 BIRC3baculoviral IAP repeat-containing 3 (210538_s_at), score: 0.54 BMP7bone morphogenetic protein 7 (209590_at), score: 0.56 C14orf135chromosome 14 open reading frame 135 (219972_s_at), score: -0.51 C14orf169chromosome 14 open reading frame 169 (219526_at), score: -0.74 C20orf39chromosome 20 open reading frame 39 (219310_at), score: 0.64 C8orf4chromosome 8 open reading frame 4 (218541_s_at), score: -0.51 CAND2cullin-associated and neddylation-dissociated 2 (putative) (213547_at), score: -0.6 CD24CD24 molecule (209771_x_at), score: 0.62 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (205532_s_at), score: 0.55 CELSR1cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) (41660_at), score: 0.73 CELSR3cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) (40020_at), score: 0.75 CFIcomplement factor I (203854_at), score: 0.51 CHMP1Achromatin modifying protein 1A (201933_at), score: 0.54 CHMP7CHMP family, member 7 (212313_at), score: 0.49 CLEC11AC-type lectin domain family 11, member A (211709_s_at), score: -0.55 COL3A1collagen, type III, alpha 1 (215076_s_at), score: -0.63 CPEB3cytoplasmic polyadenylation element binding protein 3 (205773_at), score: -0.51 CUGBP2CUG triplet repeat, RNA binding protein 2 (202158_s_at), score: -0.55 CYB561cytochrome b-561 (209163_at), score: 0.5 CYB5R2cytochrome b5 reductase 2 (220230_s_at), score: -0.53 DCNdecorin (211896_s_at), score: -0.52 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: 0.65 DLX4distal-less homeobox 4 (208216_at), score: 0.56 DNAJC6DnaJ (Hsp40) homolog, subfamily C, member 6 (204720_s_at), score: -0.51 DRG1developmentally regulated GTP binding protein 1 (202810_at), score: 0.51 EGLN3egl nine homolog 3 (C. elegans) (219232_s_at), score: 0.53 EIF3Deukaryotic translation initiation factor 3, subunit D (200005_at), score: 0.5 EIF4A1eukaryotic translation initiation factor 4A, isoform 1 (211787_s_at), score: 0.56 EMP1epithelial membrane protein 1 (201325_s_at), score: -0.61 ENOSF1enolase superfamily member 1 (204142_at), score: -0.55 ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 2 (209392_at), score: -0.55 EPAS1endothelial PAS domain protein 1 (200878_at), score: -0.51 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (202017_at), score: 0.57 ERGIC3ERGIC and golgi 3 (216032_s_at), score: 0.49 FAF1Fas (TNFRSF6) associated factor 1 (218080_x_at), score: -0.54 FAM174Bfamily with sequence similarity 174, member B (51158_at), score: -0.71 FAM46Cfamily with sequence similarity 46, member C (220306_at), score: -0.52 FAM65Bfamily with sequence similarity 65, member B (209829_at), score: -0.58 FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32) (203561_at), score: 0.65 FGF13fibroblast growth factor 13 (205110_s_at), score: 0.57 FLJ10357hypothetical protein FLJ10357 (58780_s_at), score: -0.57 FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (222033_s_at), score: -0.62 FOXG1forkhead box G1 (206018_at), score: 0.59 FTLferritin, light polypeptide (213187_x_at), score: 0.5 GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 2 (207014_at), score: 0.54 GAL3ST4galactose-3-O-sulfotransferase 4 (219815_at), score: -0.6 GALCgalactosylceramidase (204417_at), score: -0.63 GALNSgalactosamine (N-acetyl)-6-sulfate sulfatase (206335_at), score: 0.49 GALNT3UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (203397_s_at), score: -0.53 GAS1growth arrest-specific 1 (204457_s_at), score: -0.53 GPR126G protein-coupled receptor 126 (213094_at), score: -0.51 GPR177G protein-coupled receptor 177 (221958_s_at), score: -0.54 GPRC5BG protein-coupled receptor, family C, group 5, member B (203632_s_at), score: 0.5 GRAMD3GRAM domain containing 3 (218706_s_at), score: -0.53 GREM1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) (218469_at), score: -1 GSTP1glutathione S-transferase pi 1 (200824_at), score: 0.49 HEY1hairy/enhancer-of-split related with YRPW motif 1 (44783_s_at), score: 0.52 HHIPL2HHIP-like 2 (220283_at), score: 0.55 HIST1H2BKhistone cluster 1, H2bk (209806_at), score: -0.52 HLA-DRB1major histocompatibility complex, class II, DR beta 1 (209312_x_at), score: 0.51 HOXA10homeobox A10 (213150_at), score: -0.52 HSD17B12hydroxysteroid (17-beta) dehydrogenase 12 (217869_at), score: -0.57 HTATIP2HIV-1 Tat interactive protein 2, 30kDa (209448_at), score: -0.52 HYPKHuntingtin interacting protein K (218680_x_at), score: 0.51 IGSF3immunoglobulin superfamily, member 3 (202421_at), score: 0.84 IL10RBinterleukin 10 receptor, beta (209575_at), score: 0.49 IL23Ainterleukin 23, alpha subunit p19 (211796_s_at), score: -0.62 IPWimprinted in Prader-Willi syndrome (non-protein coding) (221974_at), score: -0.64 ISL1ISL LIM homeobox 1 (206104_at), score: -0.63 KYNUkynureninase (L-kynurenine hydrolase) (217388_s_at), score: 0.91 LAPTM5lysosomal multispanning membrane protein 5 (201721_s_at), score: 0.61 LEF1lymphoid enhancer-binding factor 1 (221558_s_at), score: 0.72 LOC728855hypothetical LOC728855 (222001_x_at), score: 0.5 LPPR4plasticity related gene 1 (213496_at), score: -0.6 LTBP2latent transforming growth factor beta binding protein 2 (204682_at), score: -0.53 LUMlumican (201744_s_at), score: -0.75 LXNlatexin (218729_at), score: -0.54 LYPD1LY6/PLAUR domain containing 1 (212909_at), score: 0.52 MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 (209737_at), score: -0.52 MAPRE3microtubule-associated protein, RP/EB family, member 3 (203842_s_at), score: 0.55 ME1malic enzyme 1, NADP(+)-dependent, cytosolic (204058_at), score: -0.52 MED23mediator complex subunit 23 (218846_at), score: -0.54 MED31mediator complex subunit 31 (219318_x_at), score: 0.51 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: -0.58 MLF1myeloid leukemia factor 1 (204784_s_at), score: 0.56 MLLT3myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (204918_s_at), score: -0.6 MMEmembrane metallo-endopeptidase (203434_s_at), score: -0.52 MOXD1monooxygenase, DBH-like 1 (209708_at), score: -0.54 MPPED2metallophosphoesterase domain containing 2 (205413_at), score: 0.83 MTHFS5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) (203433_at), score: 0.49 MYO1Bmyosin IB (212364_at), score: -0.78 NDRG1N-myc downstream regulated 1 (200632_s_at), score: 0.5 NESnestin (218678_at), score: -0.56 NETO2neuropilin (NRP) and tolloid (TLL)-like 2 (218888_s_at), score: -0.56 NPAS2neuronal PAS domain protein 2 (39549_at), score: -0.55 NPTX1neuronal pentraxin I (204684_at), score: 0.58 NRN1neuritin 1 (218625_at), score: 0.54 NT5E5'-nucleotidase, ecto (CD73) (203939_at), score: -0.56 OR2A9Polfactory receptor, family 2, subfamily A, member 9 pseudogene (222290_at), score: -0.53 PCLOpiccolo (presynaptic cytomatrix protein) (213558_at), score: 0.65 PCTK2PCTAIRE protein kinase 2 (221918_at), score: -0.57 PDGFRAplatelet-derived growth factor receptor, alpha polypeptide (203131_at), score: -0.68 PDLIM4PDZ and LIM domain 4 (214175_x_at), score: -0.57 PEX5peroxisomal biogenesis factor 5 (203244_at), score: 0.54 PFDN2prefoldin subunit 2 (218336_at), score: 0.55 PGAP1post-GPI attachment to proteins 1 (213469_at), score: -0.52 PID1phosphotyrosine interaction domain containing 1 (219093_at), score: -0.51 PLAG1pleiomorphic adenoma gene 1 (205372_at), score: -0.54 PLAGL1pleiomorphic adenoma gene-like 1 (209318_x_at), score: -0.52 PLCB1phospholipase C, beta 1 (phosphoinositide-specific) (213222_at), score: -0.54 PLCG1phospholipase C, gamma 1 (202789_at), score: 0.53 PLK2polo-like kinase 2 (Drosophila) (201939_at), score: 0.53 PPP2R2Bprotein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform (213849_s_at), score: 0.5 PSMB6proteasome (prosome, macropain) subunit, beta type, 6 (208827_at), score: 0.51 PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (211609_x_at), score: 0.51 PSTPIP2proline-serine-threonine phosphatase interacting protein 2 (219938_s_at), score: -0.69 PTPRDprotein tyrosine phosphatase, receptor type, D (214043_at), score: -0.67 RARBretinoic acid receptor, beta (205080_at), score: 0.57 RECKreversion-inducing-cysteine-rich protein with kazal motifs (205407_at), score: -0.53 RGS4regulator of G-protein signaling 4 (204337_at), score: -0.55 RIPK4receptor-interacting serine-threonine kinase 4 (221215_s_at), score: 0.7 RND3Rho family GTPase 3 (212724_at), score: -0.65 RP2retinitis pigmentosa 2 (X-linked recessive) (205191_at), score: -0.53 RPS6KA1ribosomal protein S6 kinase, 90kDa, polypeptide 1 (203379_at), score: 0.52 S100A4S100 calcium binding protein A4 (203186_s_at), score: -0.54 SALL2sal-like 2 (Drosophila) (213283_s_at), score: -0.55 SAV1salvador homolog 1 (Drosophila) (218276_s_at), score: -0.53 SCRIBscribbled homolog (Drosophila) (212556_at), score: -0.55 SEMA3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (35666_at), score: -0.55 SENP6SUMO1/sentrin specific peptidase 6 (202318_s_at), score: -0.51 SERPINB9serpin peptidase inhibitor, clade B (ovalbumin), member 9 (209723_at), score: -0.62 SGK1serum/glucocorticoid regulated kinase 1 (201739_at), score: -0.54 SH3BGRSH3 domain binding glutamic acid-rich protein (204979_s_at), score: 0.57 SIM1single-minded homolog 1 (Drosophila) (206876_at), score: -0.54 SLC30A1solute carrier family 30 (zinc transporter), member 1 (212907_at), score: -0.58 SLC38A4solute carrier family 38, member 4 (220786_s_at), score: -0.61 SMA4glucuronidase, beta pseudogene (215599_at), score: 0.5 SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (211989_at), score: 0.51 SNF8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (218391_at), score: 0.49 SOCS5suppressor of cytokine signaling 5 (209647_s_at), score: -0.55 SPANXCSPANX family, member C (220217_x_at), score: 0.67 STAT6signal transducer and activator of transcription 6, interleukin-4 induced (201331_s_at), score: -0.54 STIM1stromal interaction molecule 1 (202764_at), score: 0.51 STOMstomatin (201060_x_at), score: -0.52 SULF1sulfatase 1 (212353_at), score: -0.57 SULT1A1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (203615_x_at), score: 0.6 SULT1A2sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (207122_x_at), score: 0.55 SYNGR1synaptogyrin 1 (210613_s_at), score: -0.59 TBXA2Rthromboxane A2 receptor (336_at), score: -0.65 TCF12transcription factor 12 (208986_at), score: -0.52 TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box) (212761_at), score: -0.64 TEStestis derived transcript (3 LIM domains) (202720_at), score: -0.69 TGFB2transforming growth factor, beta 2 (220407_s_at), score: 0.58 TGFBItransforming growth factor, beta-induced, 68kDa (201506_at), score: 0.55 TGIF2TGFB-induced factor homeobox 2 (216262_s_at), score: 0.57 THBS2thrombospondin 2 (203083_at), score: -0.62 TMEM30Atransmembrane protein 30A (217743_s_at), score: -0.57 TNS1tensin 1 (221748_s_at), score: -0.6 TOR3Atorsin family 3, member A (218459_at), score: 0.5 TPBGtrophoblast glycoprotein (203476_at), score: -0.57 TRPC3transient receptor potential cation channel, subfamily C, member 3 (210814_at), score: 0.56 TRPS1trichorhinophalangeal syndrome I (218502_s_at), score: -0.52 TSPYL5TSPY-like 5 (213122_at), score: -0.63 TUBB6tubulin, beta 6 (209191_at), score: -0.52 ULK2unc-51-like kinase 2 (C. elegans) (204062_s_at), score: -0.59 VAV3vav 3 guanine nucleotide exchange factor (218807_at), score: 0.6 VGLL3vestigial like 3 (Drosophila) (220327_at), score: -0.53 ZBTB6zinc finger and BTB domain containing 6 (206098_at), score: -0.51 ZNF215zinc finger protein 215 (220214_at), score: -0.56 ZNF518Azinc finger protein 518A (204291_at), score: -0.57
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-4219-raw-cel-1311956178.cel | 6 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956824.cel | 24 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956358.cel | 10 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956418.cel | 13 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956321.cel | 9 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956457.cel | 14 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956138.cel | 4 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956614.cel | 18 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
