Under-expression is coded with green,
over-expression with red color.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
regulation of leukocyte migration
Any process that modulates the frequency, rate, or extent of leukocyte migration.
defense response
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
lipid metabolic process
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
cell motion
Any process involved in the controlled movement of a cell.
chemotaxis
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
behavior
The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
locomotory behavior
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cell proliferation
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
positive regulation of cell proliferation
Any process that activates or increases the rate or extent of cell proliferation.
response to external stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
response to wounding
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cell migration
The orderly movement of cells from one site to another, often during the development of a multicellular organism or multicellular structure.
regulation of lipid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
regulation of cell migration
Any process that modulates the frequency, rate or extent of cell migration.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
regulation of localization
Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
locomotion
Self-propelled movement of a cell or organism from one location to another.
regulation of locomotion
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
wound healing
The series of events that restore integrity to a damaged tissue, following an injury.
regulation of cell proliferation
Any process that modulates the frequency, rate or extent of cell proliferation.
response to chemical stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
taxis
The directed movement of a motile cell or organism in response to an external stimulus.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
cell motility
Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
leukocyte migration
The movement of leukocytes within or between different tissues and organs of the body.
localization
Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
regulation of cell motion
Any process that modulates the frequency, rate or extent of the movement of a cell.
localization of cell
Any process by which a cell is transported to, and/or maintained in, a specific location.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
all
This term is the most general term possible
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
regulation of locomotion
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
regulation of localization
Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of leukocyte migration
Any process that modulates the frequency, rate, or extent of leukocyte migration.
cell motility
Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.
positive regulation of cell proliferation
Any process that activates or increases the rate or extent of cell proliferation.
regulation of cell proliferation
Any process that modulates the frequency, rate or extent of cell proliferation.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of cell motion
Any process that modulates the frequency, rate or extent of the movement of a cell.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
regulation of cell motion
Any process that modulates the frequency, rate or extent of the movement of a cell.
response to wounding
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
taxis
The directed movement of a motile cell or organism in response to an external stimulus.
chemotaxis
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
cell motion
Any process involved in the controlled movement of a cell.
regulation of lipid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
regulation of cell migration
Any process that modulates the frequency, rate or extent of cell migration.
positive regulation of cell proliferation
Any process that activates or increases the rate or extent of cell proliferation.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
regulation of leukocyte migration
Any process that modulates the frequency, rate, or extent of leukocyte migration.
regulation of cell migration
Any process that modulates the frequency, rate or extent of cell migration.
leukocyte migration
The movement of leukocytes within or between different tissues and organs of the body.
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
taxis
The directed movement of a motile cell or organism in response to an external stimulus.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
MHC class I protein complex
A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
MHC protein complex
A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
MHC protein complex
A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.
protein binding
Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
serine-type peptidase activity
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
peptidase activity
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
receptor binding
Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
signal transducer activity
Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.
receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
transmembrane receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.
cytokine activity
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
binding
The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
growth factor activity
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
peptidase activity, acting on L-amino acid peptides
Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
hydrolase activity
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
serine hydrolase activity
Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
MHC class I receptor activity
Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.
molecular transducer activity
The molecular function that accepts an input of one form and creates an output of a different form.
all
This term is the most general term possible
serine-type peptidase activity
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Id | Pvalue | ExpCount | Count | Size | Term |
---|---|---|---|---|---|
04060 | 2.759e-04 | 4.565 | 17 | 122 | Cytokine-cytokine receptor interaction |
04610 | 4.339e-04 | 1.272 | 9 | 34 | Complement and coagulation cascades |
05332 | 8.054e-03 | 0.7858 | 6 | 21 | Graft-versus-host disease |
04630 | 2.369e-02 | 3.293 | 11 | 88 | Jak-STAT signaling pathway |
05330 | 4.694e-02 | 0.7858 | 5 | 21 | Allograft rejection |
ABCA1ATP-binding cassette, sub-family A (ABC1), member 1 (203504_s_at), score: 0.19 ABLIM3actin binding LIM protein family, member 3 (205730_s_at), score: 0.21 ACSL1acyl-CoA synthetase long-chain family member 1 (201963_at), score: 0.24 ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide (209612_s_at), score: 0.37 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: 0.42 AEBP1AE binding protein 1 (201792_at), score: 0.21 AJAP1adherens junctions associated protein 1 (206460_at), score: 0.24 AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (209160_at), score: 0.29 ANGPTL4angiopoietin-like 4 (221009_s_at), score: 0.36 ANO1anoctamin 1, calcium activated chloride channel (218804_at), score: 0.24 APODapolipoprotein D (201525_at), score: 0.37 AQP1aquaporin 1 (Colton blood group) (209047_at), score: 0.24 ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (206414_s_at), score: 0.33 ATP13A3ATPase type 13A3 (219558_at), score: 0.2 ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (212361_s_at), score: 0.18 B4GALT6UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 (206233_at), score: -0.66 BDKRB1bradykinin receptor B1 (207510_at), score: 0.21 BHLHE40basic helix-loop-helix family, member e40 (201170_s_at), score: 0.18 BMP2bone morphogenetic protein 2 (205289_at), score: 0.27 C11orf20chromosome 11 open reading frame 20 (219883_at), score: -0.64 C13orf15chromosome 13 open reading frame 15 (218723_s_at), score: 0.2 C17orf91chromosome 17 open reading frame 91 (214696_at), score: 0.2 C1Rcomplement component 1, r subcomponent (212067_s_at), score: 0.4 C1RLcomplement component 1, r subcomponent-like (218983_at), score: 0.2 C1Scomplement component 1, s subcomponent (208747_s_at), score: 0.3 C20orf27chromosome 20 open reading frame 27 (50314_i_at), score: -0.63 CADPS2Ca++-dependent secretion activator 2 (219572_at), score: 0.23 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: 0.2 CASP4caspase 4, apoptosis-related cysteine peptidase (209310_s_at), score: 0.22 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (209682_at), score: 0.26 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: 0.32 CCND2cyclin D2 (200953_s_at), score: -0.63 CCRL1chemokine (C-C motif) receptor-like 1 (220351_at), score: 0.48 CD302CD302 molecule (203799_at), score: 0.37 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: 0.24 CD97CD97 molecule (202910_s_at), score: 0.24 CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae) (208022_s_at), score: 0.21 CDC42SE1CDC42 small effector 1 (218157_x_at), score: 0.32 CLEC2BC-type lectin domain family 2, member B (209732_at), score: 0.37 CLEC7AC-type lectin domain family 7, member A (221698_s_at), score: -0.66 COL13A1collagen, type XIII, alpha 1 (211343_s_at), score: 0.21 COL14A1collagen, type XIV, alpha 1 (212865_s_at), score: 0.37 COL15A1collagen, type XV, alpha 1 (203477_at), score: 0.49 CPNE3copine III (202118_s_at), score: 0.2 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: 0.47 CSF1colony stimulating factor 1 (macrophage) (209716_at), score: 0.33 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: 0.28 CST3cystatin C (201360_at), score: 0.28 CTSAcathepsin A (200661_at), score: 0.2 CTSBcathepsin B (213274_s_at), score: 0.19 CTSKcathepsin K (202450_s_at), score: 0.2 CTSL1cathepsin L1 (202087_s_at), score: 0.26 CTSOcathepsin O (203758_at), score: 0.19 CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (204470_at), score: 0.24 CXCL2chemokine (C-X-C motif) ligand 2 (209774_x_at), score: 0.22 CXCL3chemokine (C-X-C motif) ligand 3 (207850_at), score: 0.31 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: 0.2 DCNdecorin (211896_s_at), score: 0.3 DDX3YDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (205000_at), score: 0.26 DESdesmin (202222_s_at), score: -1 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: 0.22 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: 0.57 DOCK9dedicator of cytokinesis 9 (212538_at), score: 0.21 DPP4dipeptidyl-peptidase 4 (211478_s_at), score: 0.41 DPTdermatopontin (213068_at), score: 0.29 DUSP14dual specificity phosphatase 14 (203367_at), score: 0.23 ECM1extracellular matrix protein 1 (209365_s_at), score: 0.38 EGLN2egl nine homolog 2 (C. elegans) (220956_s_at), score: -0.61 EGR2early growth response 2 (Krox-20 homolog, Drosophila) (205249_at), score: 0.24 EGR3early growth response 3 (206115_at), score: 0.32 EXD3exonuclease 3'-5' domain containing 3 (220838_at), score: -0.64 F10coagulation factor X (205620_at), score: 0.31 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: 0.38 FGF2fibroblast growth factor 2 (basic) (204421_s_at), score: 0.24 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: 0.36 FHOD1formin homology 2 domain containing 1 (218530_at), score: 0.19 FLGfilaggrin (215704_at), score: -0.62 FNDC3Afibronectin type III domain containing 3A (202304_at), score: 0.28 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: 0.37 GAAglucosidase, alpha; acid (202812_at), score: 0.27 GAP43growth associated protein 43 (204471_at), score: -0.8 GCH1GTP cyclohydrolase 1 (204224_s_at), score: 0.22 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: 0.26 GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (206355_at), score: -0.62 GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (212959_s_at), score: 0.23 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: 0.68 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: 0.2 GRAMD3GRAM domain containing 3 (218706_s_at), score: 0.21 GRNgranulin (211284_s_at), score: 0.33 GSTT1glutathione S-transferase theta 1 (203815_at), score: 0.19 HBEGFheparin-binding EGF-like growth factor (203821_at), score: 0.31 HIST1H4Ehistone cluster 1, H4e (206951_at), score: -0.63 HK2hexokinase 2 (202934_at), score: 0.45 HLA-Amajor histocompatibility complex, class I, A (217436_x_at), score: 0.27 HLA-Bmajor histocompatibility complex, class I, B (211911_x_at), score: 0.31 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: 0.38 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: 0.41 HLA-Fmajor histocompatibility complex, class I, F (204806_x_at), score: 0.32 HLXH2.0-like homeobox (214438_at), score: 0.2 HMGN1high-mobility group nucleosome binding domain 1 (200944_s_at), score: -0.67 HMOX1heme oxygenase (decycling) 1 (203665_at), score: 0.34 HOXC10homeobox C10 (218959_at), score: 0.31 HPCAL1hippocalcin-like 1 (205462_s_at), score: 0.33 HSD17B11hydroxysteroid (17-beta) dehydrogenase 11 (217989_at), score: 0.23 HSPB7heat shock 27kDa protein family, member 7 (cardiovascular) (218934_s_at), score: 0.36 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: 0.29 HTRA1HtrA serine peptidase 1 (201185_at), score: 0.25 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: 0.26 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: 0.28 IDUAiduronidase, alpha-L- (205059_s_at), score: 0.2 IFITM1interferon induced transmembrane protein 1 (9-27) (214022_s_at), score: 0.31 IL11interleukin 11 (206924_at), score: 0.21 IL15RAinterleukin 15 receptor, alpha (207375_s_at), score: 0.21 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: 0.32 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: 0.6 IL33interleukin 33 (209821_at), score: 0.23 IL6interleukin 6 (interferon, beta 2) (205207_at), score: 0.53 IL8interleukin 8 (202859_x_at), score: 0.37 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: -0.66 ITPR3inositol 1,4,5-triphosphate receptor, type 3 (201189_s_at), score: 0.28 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: 0.29 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: 0.37 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: 0.4 KANK1KN motif and ankyrin repeat domains 1 (213005_s_at), score: 0.2 KHDRBS3KH domain containing, RNA binding, signal transduction associated 3 (209781_s_at), score: 0.3 KIAA0247KIAA0247 (202181_at), score: 0.22 KIAA1644KIAA1644 (52837_at), score: 0.36 KLHL21kelch-like 21 (Drosophila) (203068_at), score: 0.25 LEPROTleptin receptor overlapping transcript (202378_s_at), score: 0.24 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: 0.19 LGR4leucine-rich repeat-containing G protein-coupled receptor 4 (218326_s_at), score: -0.66 LHFPlipoma HMGIC fusion partner (218656_s_at), score: 0.43 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: 0.23 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: 0.36 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: 0.34 LOC100128809similar to hCG2045829 (215707_s_at), score: 0.2 LOC286434hypothetical protein LOC286434 (222196_at), score: -0.66 LRIG1leucine-rich repeats and immunoglobulin-like domains 1 (211596_s_at), score: 0.24 LRRC15leucine rich repeat containing 15 (213909_at), score: 0.28 LY96lymphocyte antigen 96 (206584_at), score: 0.37 MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 (209737_at), score: 0.21 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.38 MAN2B1mannosidase, alpha, class 2B, member 1 (209166_s_at), score: 0.32 MARCH7membrane-associated ring finger (C3HC4) 7 (202654_x_at), score: 0.19 MEIS1Meis homeobox 1 (204069_at), score: 0.21 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: 0.26 MEOX1mesenchyme homeobox 1 (205619_s_at), score: -0.67 MFAP4microfibrillar-associated protein 4 (212713_at), score: 0.32 MTSS1metastasis suppressor 1 (203037_s_at), score: 0.31 MUC3Amucin 3A, cell surface associated (217117_x_at), score: -0.63 MYO1Dmyosin ID (212338_at), score: 0.45 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: 0.42 NET1neuroepithelial cell transforming 1 (201830_s_at), score: 0.2 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: 0.38 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: 0.36 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: 0.44 NID1nidogen 1 (202008_s_at), score: 0.24 NINJ1ninjurin 1 (203045_at), score: 0.28 NKX3-1NK3 homeobox 1 (209706_at), score: 0.21 NLGN4Xneuroligin 4, X-linked (221933_at), score: -0.74 NPnucleoside phosphorylase (201695_s_at), score: 0.22 NPC1Niemann-Pick disease, type C1 (202679_at), score: 0.3 NPC2Niemann-Pick disease, type C2 (200701_at), score: 0.43 NPTX1neuronal pentraxin I (204684_at), score: 0.28 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: 0.26 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: 0.44 NT5DC25'-nucleotidase domain containing 2 (218051_s_at), score: -0.66 OLFML2Aolfactomedin-like 2A (213075_at), score: 0.29 OSTM1osteopetrosis associated transmembrane protein 1 (218196_at), score: 0.24 PCTK2PCTAIRE protein kinase 2 (221918_at), score: 0.21 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: 0.26 PDGFDplatelet derived growth factor D (219304_s_at), score: 0.32 PHLDA1pleckstrin homology-like domain, family A, member 1 (217997_at), score: 0.22 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: 0.29 PKP2plakophilin 2 (207717_s_at), score: 0.23 PLA2G4Cphospholipase A2, group IVC (cytosolic, calcium-independent) (209785_s_at), score: 0.21 PLAURplasminogen activator, urokinase receptor (211924_s_at), score: 0.21 PLSCR4phospholipid scramblase 4 (218901_at), score: 0.23 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: 0.44 POLR1Cpolymerase (RNA) I polypeptide C, 30kDa (207515_s_at), score: 0.19 PPAP2Aphosphatidic acid phosphatase type 2A (209147_s_at), score: 0.37 PPARDperoxisome proliferator-activated receptor delta (37152_at), score: 0.42 PPLperiplakin (203407_at), score: 0.35 PROS1protein S (alpha) (207808_s_at), score: 0.19 PSG4pregnancy specific beta-1-glycoprotein 4 (208191_x_at), score: 0.25 PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (209040_s_at), score: 0.2 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: 0.29 PTNpleiotrophin (209466_x_at), score: 0.21 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: 0.33 RCAN2regulator of calcineurin 2 (203498_at), score: 0.43 RCL1RNA terminal phosphate cyclase-like 1 (218544_s_at), score: 0.23 RGS3regulator of G-protein signaling 3 (203823_at), score: 0.39 RPL7P24ribosomal protein L7 pseudogene 24 (217092_x_at), score: -0.64 RPS4Y1ribosomal protein S4, Y-linked 1 (201909_at), score: 0.34 RRADRas-related associated with diabetes (204803_s_at), score: 0.52 RUNX1runt-related transcription factor 1 (209360_s_at), score: 0.26 SAT1spermidine/spermine N1-acetyltransferase 1 (213988_s_at), score: 0.24 SCARB2scavenger receptor class B, member 2 (201647_s_at), score: 0.19 SCPEP1serine carboxypeptidase 1 (218217_at), score: 0.26 SECTM1secreted and transmembrane 1 (213716_s_at), score: 0.32 SEMA4Gsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G (219194_at), score: -0.62 SEMA5Asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (205405_at), score: 0.22 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: 0.29 SFRS5splicing factor, arginine/serine-rich 5 (212266_s_at), score: 0.22 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: 0.3 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: 0.29 SLC2A10solute carrier family 2 (facilitated glucose transporter), member 10 (221024_s_at), score: 0.21 SLC39A8solute carrier family 39 (zinc transporter), member 8 (209267_s_at), score: 0.32 SLCO3A1solute carrier organic anion transporter family, member 3A1 (219229_at), score: 0.21 SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (201074_at), score: -0.62 SMOXspermine oxidase (210357_s_at), score: 0.23 SOCS2suppressor of cytokine signaling 2 (203373_at), score: 0.24 SOD2superoxide dismutase 2, mitochondrial (221477_s_at), score: 0.27 SOD3superoxide dismutase 3, extracellular (205236_x_at), score: 0.39 SOX11SRY (sex determining region Y)-box 11 (204914_s_at), score: -0.72 SOX4SRY (sex determining region Y)-box 4 (201417_at), score: 0.23 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: 0.27 SPRY2sprouty homolog 2 (Drosophila) (204011_at), score: 0.26 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: 0.28 SQRDLsulfide quinone reductase-like (yeast) (217995_at), score: 0.23 STC1stanniocalcin 1 (204597_x_at), score: 0.2 STK38Lserine/threonine kinase 38 like (212572_at), score: 0.28 STOMstomatin (201060_x_at), score: 0.25 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: 0.37 TBX3T-box 3 (219682_s_at), score: 0.32 TCOF1Treacher Collins-Franceschetti syndrome 1 (202385_s_at), score: -0.61 TEX2testis expressed 2 (218099_at), score: 0.27 THBDthrombomodulin (203887_s_at), score: 0.38 TIPARPTCDD-inducible poly(ADP-ribose) polymerase (212665_at), score: 0.22 TM2D1TM2 domain containing 1 (211703_s_at), score: 0.36 TMBIM4transmembrane BAX inhibitor motif containing 4 (219206_x_at), score: 0.23 TMEM158transmembrane protein 158 (213338_at), score: 0.25 TMEM41Btransmembrane protein 41B (212623_at), score: 0.41 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: 0.42 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (210260_s_at), score: 0.26 TNFRSF11Btumor necrosis factor receptor superfamily, member 11b (204933_s_at), score: 0.39 TNFRSF1Btumor necrosis factor receptor superfamily, member 1B (203508_at), score: 0.2 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: 0.22 TNS3tensin 3 (217853_at), score: 0.28 TNXAtenascin XA pseudogene (213451_x_at), score: 0.21 TNXBtenascin XB (216333_x_at), score: 0.29 TOM1target of myb1 (chicken) (202807_s_at), score: 0.2 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: 0.28 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: 0.21 TPP1tripeptidyl peptidase I (200742_s_at), score: 0.4 TPST1tyrosylprotein sulfotransferase 1 (204140_at), score: 0.28 TPST2tyrosylprotein sulfotransferase 2 (204079_at), score: 0.19 TRAF3TNF receptor-associated factor 3 (221571_at), score: 0.21 TRAF3IP2TRAF3 interacting protein 2 (215411_s_at), score: 0.27 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: 0.32 TRIM22tripartite motif-containing 22 (213293_s_at), score: 0.29 USP22ubiquitin specific peptidase 22 (200083_at), score: -0.66 UTP3UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) (209486_at), score: 0.2 VEGFAvascular endothelial growth factor A (211527_x_at), score: 0.29 WISP2WNT1 inducible signaling pathway protein 2 (205792_at), score: 0.48 WTAPWilms tumor 1 associated protein (210285_x_at), score: 0.38 YRDCyrdC domain containing (E. coli) (218647_s_at), score: 0.21 ZBTB20zinc finger and BTB domain containing 20 (205383_s_at), score: 0.23 ZKSCAN3zinc finger with KRAB and SCAN domains 3 (211773_s_at), score: -0.63 ZMYM6zinc finger, MYM-type 6 (219924_s_at), score: 0.22 ZNF35zinc finger protein 35 (206096_at), score: 0.2 ZNF672zinc finger protein 672 (218068_s_at), score: 0.21
Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
---|---|---|---|---|---|---|
1Twin.CEL | 1 | 2 | DS-twin | hgu133plus2 | Down | DS-twin 1 |
6Twin.CEL | 6 | 2 | DS-twin | hgu133plus2 | none | DS-twin 6 |
2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
5CTwin.CEL | 5 | 2 | DS-twin | hgu133plus2 | Down | DS-twin 5 |
t21c 08-03.CEL | 6 | 1 | DS-CC | hgu133a | Down | DS-CC 6 |
t21b 08-03.CEL | 5 | 1 | DS-CC | hgu133a | Down | DS-CC 5 |
t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
ctrl b 08-03.CEL | 2 | 1 | DS-CC | hgu133a | none | DS-CC 2 |