Under-expression is coded with green,
over-expression with red color.
MAPKKK cascade
Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
phosphorus metabolic process
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
phosphate metabolic process
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
intracellular signaling cascade
A series of reactions within the cell that occur as a result of a single trigger reaction or compound.
protein kinase cascade
A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.
JNK cascade
A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
phosphorylation
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
stress-activated protein kinase signaling pathway
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
cellular response to stress
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
positive regulation of kinase activity
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
positive regulation of catalytic activity
Any process that activates or increases the activity of an enzyme.
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.
regulation of MAP kinase activity
Any process that modulates the frequency, rate or extent of MAP kinase activity.
positive regulation of MAP kinase activity
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
biopolymer modification
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties.
regulation of JUN kinase activity
Any process that modulates the frequency, rate or extent of JUN kinase activity.
positive regulation of JUN kinase activity
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
regulation of kinase activity
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
post-translational protein modification
The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
regulation of protein kinase activity
Any process that modulates the frequency, rate or extent of protein kinase activity.
positive regulation of protein kinase activity
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of catalytic activity
Any process that modulates the activity of an enzyme.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of transferase activity
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
cellular response to stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
regulation of molecular function
Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cellular response to stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
cellular response to stress
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
stress-activated protein kinase signaling pathway
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
positive regulation of kinase activity
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
JNK cascade
A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
positive regulation of protein kinase activity
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
positive regulation of MAP kinase activity
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
positive regulation of JUN kinase activity
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
ABCA7ATP-binding cassette, sub-family A (ABC1), member 7 (219577_s_at), score: 0.71 ABCD1ATP-binding cassette, sub-family D (ALD), member 1 (205142_x_at), score: -0.65 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: 0.73 ABLIM3actin binding LIM protein family, member 3 (205730_s_at), score: -0.6 ACTN3actinin, alpha 3 (206891_at), score: 0.85 AGRNagrin (217419_x_at), score: -0.65 AKIRIN1akirin 1 (217893_s_at), score: -0.62 ALDH1L1aldehyde dehydrogenase 1 family, member L1 (215798_at), score: 0.98 AMTaminomethyltransferase (204294_at), score: 0.71 ANKFY1ankyrin repeat and FYVE domain containing 1 (219868_s_at), score: -0.61 ANXA8L2annexin A8-like 2 (203074_at), score: 0.75 APOC4apolipoprotein C-IV (206738_at), score: 0.78 ARMC9armadillo repeat containing 9 (219637_at), score: -0.55 ARSAarylsulfatase A (204443_at), score: -0.74 ATP6V0A1ATPase, H+ transporting, lysosomal V0 subunit a1 (205095_s_at), score: -0.58 BAIAP3BAI1-associated protein 3 (216356_x_at), score: 0.75 BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (201419_at), score: -0.62 BAT2HLA-B associated transcript 2 (212081_x_at), score: -0.82 BAT2LHLA-B associated transcript 2-like (212068_s_at), score: -0.74 BCANbrevican (91920_at), score: 0.76 BCL2L1BCL2-like 1 (215037_s_at), score: -0.57 BTNL3butyrophilin-like 3 (217207_s_at), score: 0.81 C1orf69chromosome 1 open reading frame 69 (215490_at), score: 0.77 C2orf54chromosome 2 open reading frame 54 (220149_at), score: 0.71 C2orf72chromosome 2 open reading frame 72 (213143_at), score: 0.73 C8orf60chromosome 8 open reading frame 60 (220712_at), score: 0.74 CALB1calbindin 1, 28kDa (205626_s_at), score: 0.71 CALB2calbindin 2 (205428_s_at), score: 0.78 CALCOCO1calcium binding and coiled-coil domain 1 (209002_s_at), score: -0.55 CCDC101coiled-coil domain containing 101 (48117_at), score: 0.76 CCDC41coiled-coil domain containing 41 (219644_at), score: 0.71 CD79BCD79b molecule, immunoglobulin-associated beta (205297_s_at), score: 0.83 CDAcytidine deaminase (205627_at), score: -0.64 CDC42BPBCDC42 binding protein kinase beta (DMPK-like) (217849_s_at), score: -0.64 CDC42EP1CDC42 effector protein (Rho GTPase binding) 1 (204693_at), score: -0.59 CHRNA10cholinergic receptor, nicotinic, alpha 10 (220210_at), score: 0.72 CHRNB2cholinergic receptor, nicotinic, beta 2 (neuronal) (206635_at), score: 0.72 CIZ1CDKN1A interacting zinc finger protein 1 (205516_x_at), score: -0.64 CLIP3CAP-GLY domain containing linker protein 3 (212358_at), score: -0.63 CNNM1cyclin M1 (220166_at), score: 0.72 CNOT3CCR4-NOT transcription complex, subunit 3 (203239_s_at), score: -0.55 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: 0.9 COL18A1collagen, type XVIII, alpha 1 (209081_s_at), score: -0.69 CORO1Bcoronin, actin binding protein, 1B (64486_at), score: -0.62 CRCPCGRP receptor component (203898_at), score: 0.73 CRTC3CREB regulated transcription coactivator 3 (218648_at), score: -0.62 CTSEcathepsin E (205927_s_at), score: 0.75 CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4 (205998_x_at), score: 0.73 CYTH4cytohesin 4 (219183_s_at), score: 0.74 DCAKDdephospho-CoA kinase domain containing (221224_s_at), score: 0.71 DEAF1deformed epidermal autoregulatory factor 1 (Drosophila) (209407_s_at), score: -0.58 DGCR2DiGeorge syndrome critical region gene 2 (214198_s_at), score: 0.75 DMBT1deleted in malignant brain tumors 1 (208250_s_at), score: 0.71 DMPKdystrophia myotonica-protein kinase (37996_s_at), score: -0.71 DNAJC4DnaJ (Hsp40) homolog, subfamily C, member 4 (206782_s_at), score: -0.6 DNM2dynamin 2 (202253_s_at), score: -0.56 DOK4docking protein 4 (209691_s_at), score: -0.62 DOPEY1dopey family member 1 (40612_at), score: 0.78 DRG2developmentally regulated GTP binding protein 2 (203267_s_at), score: -0.66 DSPPdentin sialophosphoprotein (221681_s_at), score: 0.93 DUS2Ldihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae) (47105_at), score: 0.78 DUSP3dual specificity phosphatase 3 (201537_s_at), score: -0.68 DUSP5dual specificity phosphatase 5 (209457_at), score: -0.56 ECE1endothelin converting enzyme 1 (201750_s_at), score: -0.66 ECM1extracellular matrix protein 1 (209365_s_at), score: -0.65 EDARectodysplasin A receptor (220048_at), score: 0.74 EFHD2EF-hand domain family, member D2 (217992_s_at), score: -0.61 EHBP1L1EH domain binding protein 1-like 1 (221755_at), score: -0.58 ENTPD1ectonucleoside triphosphate diphosphohydrolase 1 (209473_at), score: 0.75 EPHA4EPH receptor A4 (206114_at), score: 0.73 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (202017_at), score: -0.56 EPM2Aepilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (205231_s_at), score: 0.71 EPN2epsin 2 (203463_s_at), score: -0.57 ERAP2endoplasmic reticulum aminopeptidase 2 (219759_at), score: -0.57 EXOC2exocyst complex component 2 (219349_s_at), score: -0.57 F11coagulation factor XI (206610_s_at), score: 0.77 FAM102Afamily with sequence similarity 102, member A (212400_at), score: -0.57 FAM65Afamily with sequence similarity 65, member A (45749_at), score: -0.56 FBP1fructose-1,6-bisphosphatase 1 (209696_at), score: 0.78 FBXL14F-box and leucine-rich repeat protein 14 (213145_at), score: -0.65 FBXO17F-box protein 17 (220233_at), score: -0.55 FBXO2F-box protein 2 (219305_x_at), score: 0.83 FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide (204232_at), score: 0.87 FETUBfetuin B (214417_s_at), score: 0.81 FGL1fibrinogen-like 1 (205305_at), score: 0.84 FHOD1formin homology 2 domain containing 1 (218530_at), score: -0.8 FLJ40113golgi autoantigen, golgin subfamily a-like pseudogene (213212_x_at), score: 0.76 FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1) (214520_at), score: -0.77 FOXF1forkhead box F1 (205935_at), score: -0.71 FOXK2forkhead box K2 (203064_s_at), score: -0.84 FUT2fucosyltransferase 2 (secretor status included) (210608_s_at), score: 0.74 GBA3glucosidase, beta, acid 3 (cytosolic) (219954_s_at), score: 0.83 GDF9growth differentiation factor 9 (221314_at), score: 0.78 GM2AGM2 ganglioside activator (212737_at), score: -0.56 GMPRguanosine monophosphate reductase (204187_at), score: -0.68 GNL3LPguanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene (220716_at), score: 0.77 GPD1Lglycerol-3-phosphate dehydrogenase 1-like (212510_at), score: -0.6 GTPBP1GTP binding protein 1 (219357_at), score: -0.59 GZMMgranzyme M (lymphocyte met-ase 1) (207460_at), score: 0.73 HAB1B1 for mucin (215778_x_at), score: 1 HAMPhepcidin antimicrobial peptide (220491_at), score: 0.85 HAND1heart and neural crest derivatives expressed 1 (220138_at), score: 0.73 HECTD3HECT domain containing 3 (218632_at), score: -0.6 HHEXhematopoietically expressed homeobox (215933_s_at), score: -0.66 HIST1H4Dhistone cluster 1, H4d (208076_at), score: 0.72 HLA-DQB1major histocompatibility complex, class II, DQ beta 1 (211654_x_at), score: 0.79 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: -0.69 HMGA1high mobility group AT-hook 1 (210457_x_at), score: -0.66 HPCAL1hippocalcin-like 1 (205462_s_at), score: -0.6 HSD17B6hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse) (37512_at), score: 0.77 HSF1heat shock transcription factor 1 (202344_at), score: -0.75 IDUAiduronidase, alpha-L- (205059_s_at), score: -0.8 IGHMBP2immunoglobulin mu binding protein 2 (215980_s_at), score: 0.78 IL22RA1interleukin 22 receptor, alpha 1 (220056_at), score: 0.79 INE1inactivation escape 1 (non-protein coding) (207252_at), score: 0.79 INPP1inositol polyphosphate-1-phosphatase (202794_at), score: -0.67 ITGALintegrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (213475_s_at), score: 0.74 ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (204628_s_at), score: 0.72 JUNDjun D proto-oncogene (203751_x_at), score: -0.68 JUPjunction plakoglobin (201015_s_at), score: -0.81 KAL1Kallmann syndrome 1 sequence (205206_at), score: 0.85 KCTD13potassium channel tetramerisation domain containing 13 (45653_at), score: -0.56 KIAA0317KIAA0317 (202128_at), score: -0.68 KIAA1305KIAA1305 (220911_s_at), score: -0.67 KLHL23kelch-like 23 (Drosophila) (213610_s_at), score: 0.73 KLHL26kelch-like 26 (Drosophila) (219354_at), score: -0.75 KRT24keratin 24 (220267_at), score: 0.76 LEPREL2leprecan-like 2 (204854_at), score: -0.76 LLGL2lethal giant larvae homolog 2 (Drosophila) (203713_s_at), score: 0.75 LOC149478hypothetical protein LOC149478 (215462_at), score: 0.75 LOC390998similar to hCG1644589 (216589_at), score: 0.72 LOC440434hypothetical protein FLJ11822 (215090_x_at), score: -0.72 LRP5low density lipoprotein receptor-related protein 5 (209468_at), score: -0.57 MAGOH2mago-nashi homolog 2, proliferation-associated (Drosophila) (217693_x_at), score: 0.74 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: -0.69 MAP1Smicrotubule-associated protein 1S (218522_s_at), score: -0.86 MAP3K11mitogen-activated protein kinase kinase kinase 11 (203652_at), score: -0.57 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: -0.56 MAP3K6mitogen-activated protein kinase kinase kinase 6 (219278_at), score: -0.7 MAP4microtubule-associated protein 4 (200836_s_at), score: -0.55 MEOX1mesenchyme homeobox 1 (205619_s_at), score: 0.79 MGAT1mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (201126_s_at), score: -0.59 MGST2microsomal glutathione S-transferase 2 (204168_at), score: -0.56 MICAL3microtubule associated monoxygenase, calponin and LIM domain containing 3 (212715_s_at), score: -0.63 MKL1megakaryoblastic leukemia (translocation) 1 (212748_at), score: -0.59 MPP1membrane protein, palmitoylated 1, 55kDa (202974_at), score: -0.6 MRPS2mitochondrial ribosomal protein S2 (218001_at), score: -0.57 MUC5ACmucin 5AC, oligomeric mucus/gel-forming (217182_at), score: 0.74 MUL1mitochondrial E3 ubiquitin ligase 1 (218246_at), score: -0.65 MYH15myosin, heavy chain 15 (215331_at), score: 0.74 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: 0.86 MYO15Amyosin XVA (220288_at), score: 0.78 NACAP1nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 (211445_x_at), score: 0.81 NCDNneurochondrin (209556_at), score: -0.56 NCKAP1NCK-associated protein 1 (217465_at), score: 0.77 NCRNA00093non-protein coding RNA 93 (210723_x_at), score: 0.83 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: -0.69 NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (201502_s_at), score: -0.57 NINJ1ninjurin 1 (203045_at), score: -0.7 NOL10nucleolar protein 10 (218591_s_at), score: 0.71 NOVA2neuro-oncological ventral antigen 2 (206477_s_at), score: 0.89 NPDC1neural proliferation, differentiation and control, 1 (218086_at), score: -0.58 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: 0.71 NXPH3neurexophilin 3 (221991_at), score: 0.8 OBFC2Boligonucleotide/oligosaccharide-binding fold containing 2B (218903_s_at), score: -0.56 OGDHoxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (201282_at), score: -0.59 OPRL1opiate receptor-like 1 (206564_at), score: 0.78 OR7E47Polfactory receptor, family 7, subfamily E, member 47 pseudogene (216698_x_at), score: 0.81 PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans) (205245_at), score: 0.74 PARVBparvin, beta (204629_at), score: -0.67 PCDHG@protocadherin gamma cluster (215836_s_at), score: -0.69 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: -0.69 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: -0.67 PDE5Aphosphodiesterase 5A, cGMP-specific (206757_at), score: -0.73 PDE7Bphosphodiesterase 7B (220343_at), score: 0.75 PGCprogastricsin (pepsinogen C) (205261_at), score: 0.76 PHF7PHD finger protein 7 (215622_x_at), score: 0.88 PI4K2Aphosphatidylinositol 4-kinase type 2 alpha (209345_s_at), score: -0.57 PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta) (207105_s_at), score: -0.56 PINK1PTEN induced putative kinase 1 (209018_s_at), score: -0.55 PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma (212518_at), score: -0.86 PKN1protein kinase N1 (202161_at), score: -0.67 PLAUplasminogen activator, urokinase (211668_s_at), score: -0.7 PLK3polo-like kinase 3 (Drosophila) (204958_at), score: -0.59 PMS2L2postmeiotic segregation increased 2-like 2 pseudogene (215410_at), score: 0.77 PNPLA6patatin-like phospholipase domain containing 6 (203718_at), score: -0.6 POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa (202725_at), score: -0.63 POLRMTpolymerase (RNA) mitochondrial (DNA directed) (203782_s_at), score: -0.55 POLSpolymerase (DNA directed) sigma (202466_at), score: -0.58 POM121POM121 membrane glycoprotein (rat) (212178_s_at), score: -0.57 PORP450 (cytochrome) oxidoreductase (208928_at), score: -0.67 PRKCBprotein kinase C, beta (209685_s_at), score: 0.76 PRKCDprotein kinase C, delta (202545_at), score: -0.69 PTPN6protein tyrosine phosphatase, non-receptor type 6 (206687_s_at), score: 0.84 PTPROprotein tyrosine phosphatase, receptor type, O (211600_at), score: -0.64 PXNpaxillin (211823_s_at), score: -0.79 PYGBphosphorylase, glycogen; brain (201481_s_at), score: -0.55 RAB11BRAB11B, member RAS oncogene family (34478_at), score: -0.56 RAB11FIP3RAB11 family interacting protein 3 (class II) (203933_at), score: -0.56 RAB22ARAB22A, member RAS oncogene family (218360_at), score: -0.6 RABL4RAB, member of RAS oncogene family-like 4 (205037_at), score: -0.56 REG3Aregenerating islet-derived 3 alpha (205815_at), score: 0.79 RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 1 (209941_at), score: -0.65 RLN1relaxin 1 (211753_s_at), score: 0.85 RNF130ring finger protein 130 (217865_at), score: -0.66 RNF24ring finger protein 24 (204669_s_at), score: -0.58 RNF40ring finger protein 40 (206845_s_at), score: -0.61 RP3-377H14.5hypothetical LOC285830 (222279_at), score: 0.81 RP5-1000E10.4suppressor of IKK epsilon (221705_s_at), score: 0.71 RP5-886K2.1neuronal thread protein AD7c-NTP (207953_at), score: 0.76 RPL18AP6ribosomal protein L18a pseudogene 6 (216383_at), score: 0.84 RPL21P68ribosomal protein L21 pseudogene 68 (217340_at), score: 0.8 RPS17P5ribosomal protein S17 pseudogene 5 (216348_at), score: 0.93 S100A14S100 calcium binding protein A14 (218677_at), score: 0.83 SAA4serum amyloid A4, constitutive (207096_at), score: 0.75 SAV1salvador homolog 1 (Drosophila) (218276_s_at), score: -0.71 SBNO2strawberry notch homolog 2 (Drosophila) (204166_at), score: -0.59 SCAMP4secretory carrier membrane protein 4 (213244_at), score: -0.86 SCAMP5secretory carrier membrane protein 5 (212699_at), score: 0.75 SDAD1SDA1 domain containing 1 (218607_s_at), score: -0.58 SDC3syndecan 3 (202898_at), score: -0.61 SDPRserum deprivation response (phosphatidylserine binding protein) (218711_s_at), score: -0.55 SEMA3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (35666_at), score: 0.72 SH2B3SH2B adaptor protein 3 (203320_at), score: -0.58 SH3GLB2SH3-domain GRB2-like endophilin B2 (218813_s_at), score: -0.68 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: -0.65 SIGIRRsingle immunoglobulin and toll-interleukin 1 receptor (TIR) domain (52940_at), score: -0.65 SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin (44673_at), score: 0.87 SIGLEC6sialic acid binding Ig-like lectin 6 (210796_x_at), score: 0.79 SIN3BSIN3 homolog B, transcription regulator (yeast) (209352_s_at), score: -0.76 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: 0.74 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (210923_at), score: 0.72 SLC26A10solute carrier family 26, member 10 (214951_at), score: 0.74 SLC2A8solute carrier family 2 (facilitated glucose transporter), member 8 (218985_at), score: -0.61 SLC5A5solute carrier family 5 (sodium iodide symporter), member 5 (211123_at), score: 0.85 SLC6A11solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (207048_at), score: 0.87 SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 1 (209453_at), score: -0.63 SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 (209830_s_at), score: -0.73 SMG6Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) (214940_s_at), score: -0.62 SMYD5SMYD family member 5 (209516_at), score: -0.56 SNAP25synaptosomal-associated protein, 25kDa (202508_s_at), score: -0.65 SNIP1Smad nuclear interacting protein 1 (219409_at), score: -0.55 SOLHsmall optic lobes homolog (Drosophila) (204275_at), score: -0.75 SORL1sortilin-related receptor, L(DLR class) A repeats-containing (203509_at), score: 0.77 SPARCL1SPARC-like 1 (hevin) (200795_at), score: 0.74 SPATA20spermatogenesis associated 20 (218164_at), score: -0.59 SPG7spastic paraplegia 7 (pure and complicated autosomal recessive) (202104_s_at), score: -0.67 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: -0.68 SSBP3single stranded DNA binding protein 3 (217991_x_at), score: -0.63 ST5suppression of tumorigenicity 5 (202440_s_at), score: -0.55 STOMstomatin (201060_x_at), score: -0.61 SULT1B1sulfotransferase family, cytosolic, 1B, member 1 (207601_at), score: 0.82 SYT1synaptotagmin I (203999_at), score: -0.65 TAF15TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa (202840_at), score: 0.77 TAL1T-cell acute lymphocytic leukemia 1 (206283_s_at), score: 0.73 TAPBPTAP binding protein (tapasin) (208829_at), score: -0.71 TBC1D2BTBC1 domain family, member 2B (212796_s_at), score: -0.61 TERF2telomeric repeat binding factor 2 (203611_at), score: -0.72 TGFBR2transforming growth factor, beta receptor II (70/80kDa) (207334_s_at), score: -0.62 TGM4transglutaminase 4 (prostate) (217566_s_at), score: 0.75 TIAF1TGFB1-induced anti-apoptotic factor 1 (202039_at), score: -0.72 TLE6transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila) (222219_s_at), score: 0.79 TMCC2transmembrane and coiled-coil domain family 2 (213096_at), score: 0.79 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: 0.89 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: -0.64 TNFRSF8tumor necrosis factor receptor superfamily, member 8 (206729_at), score: 0.9 TNK1tyrosine kinase, non-receptor, 1 (217149_x_at), score: 0.76 TOB2transducer of ERBB2, 2 (221496_s_at), score: -0.55 TRIM45tripartite motif-containing 45 (219923_at), score: 0.71 TSC2tuberous sclerosis 2 (215735_s_at), score: -0.7 TSKUtsukushin (218245_at), score: -0.61 TUBA4Btubulin, alpha 4b (pseudogene) (207490_at), score: 0.96 TULP2tubby like protein 2 (206733_at), score: 0.77 TXLNAtaxilin alpha (212300_at), score: -0.62 UBAC1UBA domain containing 1 (202151_s_at), score: -0.58 UBTD1ubiquitin domain containing 1 (219172_at), score: -0.79 USF2upstream transcription factor 2, c-fos interacting (202152_x_at), score: -0.65 VCPIP1valosin containing protein (p97)/p47 complex interacting protein 1 (219810_at), score: 0.78 VEGFBvascular endothelial growth factor B (203683_s_at), score: -0.88 VPS37Bvacuolar protein sorting 37 homolog B (S. cerevisiae) (221704_s_at), score: -0.82 WDR4WD repeat domain 4 (221632_s_at), score: 0.72 WDR42AWD repeat domain 42A (202249_s_at), score: -0.69 WDR6WD repeat domain 6 (217734_s_at), score: -0.69 WNT2Bwingless-type MMTV integration site family, member 2B (206459_s_at), score: 0.79 WSB1WD repeat and SOCS box-containing 1 (201294_s_at), score: 0.75 XYLBxylulokinase homolog (H. influenzae) (214776_x_at), score: 0.74 ZFHX3zinc finger homeobox 3 (208033_s_at), score: -0.6 ZNF282zinc finger protein 282 (212892_at), score: -0.6
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-TABM-263-raw-cel-1515485691.cel | 3 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485871.cel | 12 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485711.cel | 4 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 46A.CEL | 1 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 1 |
| E-TABM-263-raw-cel-1515486071.cel | 22 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486211.cel | 29 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485831.cel | 10 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486411.cel | 39 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486171.cel | 27 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485991.cel | 18 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485951.cel | 16 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485791.cel | 8 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 46C.CEL | 3 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 3 |
| E-TABM-263-raw-cel-1515486151.cel | 26 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 3Twin.CEL | 3 | 2 | DS-twin | hgu133plus2 | Down | DS-twin 3 |
| 4Twin.CEL | 4 | 2 | DS-twin | hgu133plus2 | none | DS-twin 4 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| E-TABM-263-raw-cel-1515485811.cel | 9 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 6Twin.CEL | 6 | 2 | DS-twin | hgu133plus2 | none | DS-twin 6 |
| 5CTwin.CEL | 5 | 2 | DS-twin | hgu133plus2 | Down | DS-twin 5 |
| E-TABM-263-raw-cel-1515485891.cel | 13 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486091.cel | 23 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485931.cel | 15 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| E-TABM-263-raw-cel-1515485671.cel | 2 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486371.cel | 37 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
| E-TABM-263-raw-cel-1515485771.cel | 7 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485751.cel | 6 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486431.cel | 40 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
