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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

generation of precursor metabolites and energy

The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.

oxidation reduction

The process of removal or addition of one or more electrons with or without the concomitant removal or addition of a proton or protons.

respiratory electron transport chain

A process whereby a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.

oxidative phosphorylation

The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.

mitochondrial electron transport, NADH to ubiquinone

The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.

electron transport chain

A process whereby a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.

phosphorus metabolic process

The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).

phosphate metabolic process

The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

energy derivation by oxidation of organic compounds

The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

ATP synthesis coupled electron transport

The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.

mitochondrial ATP synthesis coupled electron transport

The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

cellular respiration

The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

electron transport chain

A process whereby a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.

ATP synthesis coupled electron transport

The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.

respiratory electron transport chain

A process whereby a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.

oxidative phosphorylation

The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.

mitochondrial electron transport, NADH to ubiquinone

The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

mitochondrial envelope

The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

mitochondrial respiratory chain

The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

mitochondrial respiratory chain complex I

A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.

organelle inner membrane

The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.

NADH dehydrogenase complex

An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.

organelle membrane

The lipid bilayer surrounding an organelle.

mitochondrial membrane

Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.

organelle envelope

A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.

envelope

A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

mitochondrial part

Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

mitochondrial membrane part

Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

respiratory chain complex I

Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.

respiratory chain

The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle membrane

The lipid bilayer surrounding an organelle.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

organelle envelope

A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

organelle membrane

The lipid bilayer surrounding an organelle.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

organelle envelope

A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.

organelle inner membrane

The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.

NADH dehydrogenase complex

An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

NADH dehydrogenase complex

An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.

organelle inner membrane

The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

mitochondrial membrane part

Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.

mitochondrial envelope

The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.

mitochondrial membrane

Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.

mitochondrial membrane part

Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

mitochondrial part

Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

mitochondrial respiratory chain

The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

respiratory chain complex I

Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.

mitochondrial respiratory chain complex I

A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.

mitochondrial membrane

Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.

mitochondrial part

Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

mitochondrial respiratory chain

The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

mitochondrial respiratory chain complex I

A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

NADH dehydrogenase activity

Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

NADH dehydrogenase (ubiquinone) activity

Catalysis of the reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol.

oxidoreductase activity, acting on NADH or NADPH

Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.

NADH dehydrogenase (quinone) activity

Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.

all

NA

NADH dehydrogenase (quinone) activity

Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0042773	6.362e-03	0.7928	6 COX1, ND2, ND4, ND6, NDUFA8, NDUFB9	17	ATP synthesis coupled electron transport
GO:0042775	6.362e-03	0.7928	6 COX1, ND2, ND4, ND6, NDUFA8, NDUFB9	17	mitochondrial ATP synthesis coupled electron transport
GO:0006120	9.431e-03	0.5597	5 ND2, ND4, ND6, NDUFA8, NDUFB9	12	mitochondrial electron transport, NADH to ubiquinone
GO:0022904	1.775e-02	0.9794	6 COX1, ND2, ND4, ND6, NDUFA8, NDUFB9	21	respiratory electron transport chain
GO:0043170	4.102e-02	91.69	114 AASDHPPT, AGBL2, AIRE, ALKBH2, APAF1, APTX, ARHGAP22, ATG4C, BRPF1, C17orf71, CARS2, CBFA2T2, CDC42BPB, CDKL5, CNOT2, CNOT8, CNTF, DDB1, DDX1, DDX41, DGUOK, DPY30, DUS4L, DUSP4, ECD, EIF2C2, EIF3I, FARS2, FBXO22, FGF10, FGF4, FKBP14, FKBP15, FOXN1, FUT10, GARS, GEMC1, GEMIN5, GLI3, GLMN, GRB10, GRXCR1, HELLS, HNRNPU, HOXB13, IFNAR1, IKBKB, IRAK1BP1, KDM3A, LANCL2, LONRF3, LSM10, LTA4H, MAP3K4, MAPKAPK3, MED1, MED22, MRPL44, MTIF3, MTMR3, MYB, N4BP1, NFKBIA, NIF3L1, NSUN2, PAPD4, PDE6G, PGR, PHF12, PHF21A, PHKA2, PHTF1, PIGL, PIGS, PPP1R8, PRCP, PRKACB, PRKD1, PRSSL1, PSMB4, PUS10, PUS3, RPE65, RPS6KA6, RPUSD2, SAP30L, SCML2, SCRN2, SERPINB10, SFRS8, SKIL, SMUG1, SNRK, STT3B, TAF4B, TERT, TMPRSS4, TMPRSS7, TNKS, TRIP12, TSN, TTLL1, TTLL9, TUSC3, UBE2G1, USP14, USP19, UTP20, WDR48, WDR77, ZFP91, ZNF512, ZNF800, ZNFX1	1966	macromolecule metabolic process

Id	Pvalue	ExpCount	Count	Size	Term
GO:0070469	2.933e-03	0.8313	6 COX1, ND2, ND4, ND6, NDUFA8, NDUFB9	18	respiratory chain
GO:0005747	3.294e-03	0.5542	5 ND2, ND4, ND6, NDUFA8, NDUFB9	12	mitochondrial respiratory chain complex I
GO:0030964	3.294e-03	0.5542	5 ND2, ND4, ND6, NDUFA8, NDUFB9	12	NADH dehydrogenase complex
GO:0045271	3.294e-03	0.5542	5 ND2, ND4, ND6, NDUFA8, NDUFB9	12	respiratory chain complex I
GO:0044424	3.939e-03	163.6	187 AASDHPPT, ACER1, ADC, AGBL2, AHSA2, AIRE, ALKBH2, ANXA6, APAF1, APTX, ARHGAP22, ATG4C, BBS7, BCL2L13, BLVRA, BRPF1, C14orf159, C18orf55, C1orf151, C1orf9, C2CD2, CARS2, CBFA2T2, CDC42BPB, CDCA3, CDKL5, CHMP6, CISD2, CNOT2, CNOT8, CNTF, COX1, COX4I1, DCTN5, DDB1, DDX1, DDX41, DGUOK, DNM1L, DPY30, DUSP4, ECD, EIF2C2, EIF3I, EPS15, FARS2, FBXO15, FGF10, FKBP14, FKBP15, FKTN, FOXN1, FUT10, GARS, GEMC1, GEMIN5, GLB1, GLI3, GM2A, GRB10, GRXCR1, HELLS, HNRNPU, HOXB13, HPRT1, IFT81, IK, IKBIP, IKBKB, INVS, IPP, IRAK1BP1, IWS1, KDM3A, KIAA0174, KIF14, LANCL2, LCA5, LEMD2, LEPRE1, LRAT, LSM10, LTA4H, MAP3K4, MAPKAPK3, MED1, MED22, MEMO1, MID2, MKS1, MRPL44, MTIF3, MTMR3, MYB, MYL1, N4BP1, NARF, ND2, ND4, ND6, NDUFA8, NDUFB9, NFKBIA, NIF3L1, NPSR1, NSUN2, NTS, NUF2, NUP153, NUP54, NUP85, OSTF1, PAPD4, PARK7, PFN4, PGR, PHF12, PHF21A, PHKA2, PHTF1, PIGL, PIGS, PLS3, PPA2, PPP1R8, PRCP, PRKACB, PRKD1, PSMB4, PUS3, RAB38, RABEPK, RIC8B, RPE65, RPGRIP1L, RPS6KA6, SAP30L, SCML2, SERPINB10, SERPINB2, SFRS8, SGCE, SGCZ, SGOL1, SKIL, SLC4A7, SMUG1, SNRK, SPG20, SRPX2, STAU2, STIL, STT3B, STX8, TAF4B, TDRKH, TERT, THEMIS, THYN1, TMEM18, TNKS, TOE1, TPMT, TRAF3IP1, TRIM35, TRIP12, TSN, TTLL1, TTLL9, TUFT1, TUSC3, UBTD2, UNC45A, USP14, USP19, UTP20, WDR48, WDR77, ZC3H15, ZFP91, ZFYVE1, ZMYND10, ZMYND19, ZNF512, ZNF800, ZNFX1, ZWILCH	3542	intracellular part
GO:0005746	1.172e-02	0.739	5 ND2, ND4, ND6, NDUFA8, NDUFB9	16	mitochondrial respiratory chain
GO:0005737	1.411e-02	123.4	147 AASDHPPT, ACER1, ADC, AGBL2, AHSA2, AIRE, ANXA6, APAF1, ARHGAP22, ATG4C, BBS7, BCL2L13, BLVRA, BRPF1, C14orf159, C18orf55, C1orf151, C1orf9, C2CD2, CARS2, CDC42BPB, CDCA3, CHMP6, CISD2, CNOT2, CNOT8, CNTF, COX1, COX4I1, DCTN5, DDB1, DDX1, DGUOK, DNM1L, DPY30, ECD, EIF2C2, EIF3I, EPS15, FARS2, FKBP14, FKBP15, FKTN, FUT10, GARS, GEMIN5, GLB1, GLI3, GM2A, GRB10, HNRNPU, HPRT1, IFT81, IKBIP, IKBKB, INVS, IPP, IRAK1BP1, KDM3A, KIAA0174, KIF14, LANCL2, LCA5, LEPRE1, LRAT, LTA4H, MAP3K4, MAPKAPK3, MED22, MEMO1, MID2, MKS1, MRPL44, MTIF3, MTMR3, MYL1, ND2, ND4, ND6, NDUFA8, NDUFB9, NFKBIA, NIF3L1, NPSR1, NSUN2, NTS, NUP54, NUP85, OSTF1, PAPD4, PARK7, PFN4, PGR, PHKA2, PHTF1, PIGL, PIGS, PLS3, PPA2, PPP1R8, PRCP, PRKACB, PRKD1, PSMB4, RAB38, RABEPK, RIC8B, RPE65, RPGRIP1L, RPS6KA6, SERPINB10, SERPINB2, SGCE, SGCZ, SGOL1, SKIL, SPG20, SRPX2, STAU2, STIL, STT3B, STX8, TAF4B, TDRKH, TERT, THEMIS, TNKS, TPMT, TRAF3IP1, TRIM35, TSN, TTLL1, TTLL9, TUFT1, TUSC3, UBTD2, UNC45A, USP14, USP19, UTP20, WDR48, WDR77, ZC3H15, ZFYVE1, ZMYND10, ZMYND19, ZNFX1	2671	cytoplasm
GO:0005622	1.688e-02	168.1	188 AASDHPPT, ACER1, ADC, AGBL2, AHSA2, AIRE, ALKBH2, ANXA6, APAF1, APTX, ARHGAP22, ATG4C, BBS7, BCL2L13, BLVRA, BRPF1, C14orf159, C18orf55, C1orf151, C1orf9, C2CD2, CARS2, CBFA2T2, CDC42BPB, CDCA3, CDKL5, CHMP6, CISD2, CNOT2, CNOT8, CNTF, COX1, COX4I1, DCTN5, DDB1, DDX1, DDX41, DGUOK, DNM1L, DPY30, DUSP4, ECD, EIF2C2, EIF3I, EPS15, FARS2, FBXO15, FGF10, FKBP14, FKBP15, FKTN, FOXN1, FUT10, GARS, GEMC1, GEMIN5, GLB1, GLI3, GLMN, GM2A, GRB10, GRXCR1, HELLS, HNRNPU, HOXB13, HPRT1, IFT81, IK, IKBIP, IKBKB, INVS, IPP, IRAK1BP1, IWS1, KDM3A, KIAA0174, KIF14, LANCL2, LCA5, LEMD2, LEPRE1, LRAT, LSM10, LTA4H, MAP3K4, MAPKAPK3, MED1, MED22, MEMO1, MID2, MKS1, MRPL44, MTIF3, MTMR3, MYB, MYL1, N4BP1, NARF, ND2, ND4, ND6, NDUFA8, NDUFB9, NFKBIA, NIF3L1, NPSR1, NSUN2, NTS, NUF2, NUP153, NUP54, NUP85, OSTF1, PAPD4, PARK7, PFN4, PGR, PHF12, PHF21A, PHKA2, PHTF1, PIGL, PIGS, PLS3, PPA2, PPP1R8, PRCP, PRKACB, PRKD1, PSMB4, PUS3, RAB38, RABEPK, RIC8B, RPE65, RPGRIP1L, RPS6KA6, SAP30L, SCML2, SERPINB10, SERPINB2, SFRS8, SGCE, SGCZ, SGOL1, SKIL, SLC4A7, SMUG1, SNRK, SPG20, SRPX2, STAU2, STIL, STT3B, STX8, TAF4B, TDRKH, TERT, THEMIS, THYN1, TMEM18, TNKS, TOE1, TPMT, TRAF3IP1, TRIM35, TRIP12, TSN, TTLL1, TTLL9, TUFT1, TUSC3, UBTD2, UNC45A, USP14, USP19, UTP20, WDR48, WDR77, ZC3H15, ZFP91, ZFYVE1, ZMYND10, ZMYND19, ZNF512, ZNF800, ZNFX1, ZWILCH	3640	intracellular
GO:0005634	3.190e-02	70.57	91 AGBL2, AIRE, ALKBH2, APAF1, APTX, ARHGAP22, BCL2L13, BRPF1, C2CD2, CBFA2T2, CDKL5, CNOT2, CNOT8, CNTF, COX4I1, DDB1, DDX41, DPY30, DUSP4, ECD, EIF2C2, FGF10, FKBP15, FOXN1, GEMC1, GEMIN5, GLI3, HELLS, HNRNPU, HOXB13, IK, INVS, IRAK1BP1, IWS1, KDM3A, KIF14, LANCL2, LEMD2, LSM10, LTA4H, MAPKAPK3, MED1, MED22, MEMO1, MYB, N4BP1, NARF, NFKBIA, NPSR1, NSUN2, NUF2, NUP153, NUP54, NUP85, PAPD4, PARK7, PGR, PHF12, PHF21A, PHTF1, PPP1R8, PRKACB, PSMB4, PUS3, RPS6KA6, SAP30L, SCML2, SERPINB10, SFRS8, SGOL1, SKIL, SMUG1, SNRK, STAU2, TAF4B, TERT, THEMIS, THYN1, TMEM18, TNKS, TOE1, TRIM35, TSN, UNC45A, UTP20, WDR48, WDR77, ZC3H15, ZFP91, ZNF512, ZNF800	1528	nucleus

Id	Pvalue	ExpCount	Count	Size	Term
GO:0003954	7.813e-03	0.5567	5 ND2, ND4, ND6, NDUFA8, NDUFB9	12	NADH dehydrogenase activity
GO:0008137	7.813e-03	0.5567	5 ND2, ND4, ND6, NDUFA8, NDUFB9	12	NADH dehydrogenase (ubiquinone) activity
GO:0050136	7.813e-03	0.5567	5 ND2, ND4, ND6, NDUFA8, NDUFB9	12	NADH dehydrogenase (quinone) activity
GO:0016655	1.092e-02	0.6031	5 ND2, ND4, ND6, NDUFA8, NDUFB9	13	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor

Id	Pvalue	ExpCount	Count	Size	Term
05012	1.841e-06	1.221	11 APAF1, COX1, COX4I1, CYTB, ND2, ND4, ND6, NDUFA8, NDUFB9, PARK7, UBE2G1	27	Parkinson's disease
00190	4.055e-04	1.357	9 COX1, COX4I1, CYTB, ND2, ND4, ND6, NDUFA8, NDUFB9, PPA2	30	Oxidative phosphorylation

No enriched terms

Id	Pvalue	ExpCount	Count	Size
MT	2.326e-03	0.286	5 COX1, CYTB, ND2, ND4, ND6	6

Entrez genes

AASDHPPTaminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (ENSG00000149313), score: -0.59 ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 (ENSG00000114331), score: 0.7 ACER1alkaline ceramidase 1 (ENSG00000167769), score: 0.64 ADCarginine decarboxylase (ENSG00000142920), score: 0.53 ADCY7adenylate cyclase 7 (ENSG00000121281), score: -0.52 AGBL2ATP/GTP binding protein-like 2 (ENSG00000165923), score: 0.57 AHSA2AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) (ENSG00000173209), score: -0.67 AIREautoimmune regulator (ENSG00000160224), score: 0.75 ALKBH2alkB, alkylation repair homolog 2 (E. coli) (ENSG00000189046), score: 0.57 ANXA6annexin A6 (ENSG00000197043), score: -0.56 APAF1apoptotic peptidase activating factor 1 (ENSG00000120868), score: 0.62 APTXaprataxin (ENSG00000137074), score: 0.65 ARHGAP22Rho GTPase activating protein 22 (ENSG00000128805), score: 0.59 ARSKarylsulfatase family, member K (ENSG00000164291), score: 0.54 ATG4CATG4 autophagy related 4 homolog C (S. cerevisiae) (ENSG00000125703), score: 0.6 ATP2C2ATPase, Ca++ transporting, type 2C, member 2 (ENSG00000064270), score: 0.65 BBS7Bardet-Biedl syndrome 7 (ENSG00000138686), score: 0.53 BCL2L13BCL2-like 13 (apoptosis facilitator) (ENSG00000099968), score: -0.68 BLVRAbiliverdin reductase A (ENSG00000106605), score: -0.74 BRPF1bromodomain and PHD finger containing, 1 (ENSG00000156983), score: 0.61 C10orf28chromosome 10 open reading frame 28 (ENSG00000166024), score: 0.58 C11orf46chromosome 11 open reading frame 46 (ENSG00000152219), score: 0.97 C11orf57chromosome 11 open reading frame 57 (ENSG00000150776), score: -0.58 C12orf23chromosome 12 open reading frame 23 (ENSG00000151135), score: 0.63 C13orf23chromosome 13 open reading frame 23 (ENSG00000120685), score: 0.54 C13orf31chromosome 13 open reading frame 31 (ENSG00000179630), score: 0.8 C14orf118chromosome 14 open reading frame 118 (ENSG00000089916), score: 0.59 C14orf159chromosome 14 open reading frame 159 (ENSG00000133943), score: -0.51 C17orf71chromosome 17 open reading frame 71 (ENSG00000167447), score: 0.65 C18orf55chromosome 18 open reading frame 55 (ENSG00000075336), score: -0.69 C1orf151chromosome 1 open reading frame 151 (ENSG00000173436), score: -0.52 C1orf159chromosome 1 open reading frame 159 (ENSG00000131591), score: 0.51 C1orf9chromosome 1 open reading frame 9 (ENSG00000094975), score: 0.53 C2CD2C2 calcium-dependent domain containing 2 (ENSG00000157617), score: -0.57 C3orf39chromosome 3 open reading frame 39 (ENSG00000144647), score: 0.76 C5orf30chromosome 5 open reading frame 30 (ENSG00000181751), score: 0.54 C6orf89chromosome 6 open reading frame 89 (ENSG00000198663), score: 0.63 C9orf103chromosome 9 open reading frame 103 (ENSG00000148057), score: -0.55 CA13carbonic anhydrase XIII (ENSG00000185015), score: 0.53 CARS2cysteinyl-tRNA synthetase 2, mitochondrial (putative) (ENSG00000134905), score: -0.55 CBFA2T2core-binding factor, runt domain, alpha subunit 2; translocated to, 2 (ENSG00000078699), score: 0.5 CCDC43coiled-coil domain containing 43 (ENSG00000180329), score: 0.67 CDC42BPBCDC42 binding protein kinase beta (DMPK-like) (ENSG00000198752), score: -0.67 CDCA3cell division cycle associated 3 (ENSG00000111665), score: 0.65 CDKL5cyclin-dependent kinase-like 5 (ENSG00000008086), score: 0.52 CFDP1craniofacial development protein 1 (ENSG00000153774), score: -0.53 CHMP6chromatin modifying protein 6 (ENSG00000176108), score: -0.51 CISD2CDGSH iron sulfur domain 2 (ENSG00000145354), score: -0.51 CNOT2CCR4-NOT transcription complex, subunit 2 (ENSG00000111596), score: 0.54 CNOT8CCR4-NOT transcription complex, subunit 8 (ENSG00000155508), score: 0.63 CNTFciliary neurotrophic factor (ENSG00000186660), score: 0.64 COX1cytochrome c oxidase subunit I (ENSG00000198804), score: -0.92 COX4I1cytochrome c oxidase subunit IV isoform 1 (ENSG00000131143), score: -0.65 CRTAPcartilage associated protein (ENSG00000170275), score: -0.78 CYTBcytochrome b (ENSG00000198727), score: -0.91 DCTN5dynactin 5 (p25) (ENSG00000166847), score: -0.54 DDX1DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 (ENSG00000079785), score: 0.7 DDX41DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (ENSG00000183258), score: -0.63 DENND2CDENN/MADD domain containing 2C (ENSG00000175984), score: 0.56 DGUOKdeoxyguanosine kinase (ENSG00000114956), score: -0.78 DNM1Ldynamin 1-like (ENSG00000087470), score: 0.5 DUS4Ldihydrouridine synthase 4-like (S. cerevisiae) (ENSG00000105865), score: -0.51 DUSP4dual specificity phosphatase 4 (ENSG00000120875), score: 0.7 ECDecdysoneless homolog (Drosophila) (ENSG00000122882), score: 0.94 EFCAB7EF-hand calcium binding domain 7 (ENSG00000203965), score: 0.53 EIF2C2eukaryotic translation initiation factor 2C, 2 (ENSG00000123908), score: -0.57 EIF3Ieukaryotic translation initiation factor 3, subunit I (ENSG00000084623), score: -0.58 EPS15epidermal growth factor receptor pathway substrate 15 (ENSG00000085832), score: 0.61 FAM13Cfamily with sequence similarity 13, member C (ENSG00000148541), score: 0.58 FAM179Afamily with sequence similarity 179, member A (ENSG00000189350), score: 0.51 FAM18Afamily with sequence similarity 18, member A (ENSG00000166676), score: 0.53 FAM54Afamily with sequence similarity 54, member A (ENSG00000146410), score: 0.5 FAM73Afamily with sequence similarity 73, member A (ENSG00000180488), score: 0.58 FARS2phenylalanyl-tRNA synthetase 2, mitochondrial (ENSG00000145982), score: -0.52 FBXO15F-box protein 15 (ENSG00000141665), score: 0.65 FBXO22F-box protein 22 (ENSG00000167196), score: 0.69 FGF10fibroblast growth factor 10 (ENSG00000070193), score: 0.6 FGF4fibroblast growth factor 4 (ENSG00000075388), score: 0.54 FGL2fibrinogen-like 2 (ENSG00000127951), score: -0.6 FKBP14FK506 binding protein 14, 22 kDa (ENSG00000106080), score: 0.69 FKBP15FK506 binding protein 15, 133kDa (ENSG00000119321), score: 0.55 FKTNfukutin (ENSG00000106692), score: 0.51 FLVCR1feline leukemia virus subgroup C cellular receptor 1 (ENSG00000162769), score: 0.53 FOXN1forkhead box N1 (ENSG00000109101), score: 1 FUT10fucosyltransferase 10 (alpha (1,3) fucosyltransferase) (ENSG00000172728), score: 0.84 GABREgamma-aminobutyric acid (GABA) A receptor, epsilon (ENSG00000102287), score: 0.67 GARSglycyl-tRNA synthetase (ENSG00000106105), score: 0.69 GDPD4glycerophosphodiester phosphodiesterase domain containing 4 (ENSG00000178795), score: 0.68 GEMC1geminin coiled-coil domain-containing protein 1 (ENSG00000205835), score: 0.77 GEMIN5gem (nuclear organelle) associated protein 5 (ENSG00000082516), score: 0.69 GLB1galactosidase, beta 1 (ENSG00000170266), score: -0.72 GLI3GLI family zinc finger 3 (ENSG00000106571), score: 0.55 GLMNglomulin, FKBP associated protein (ENSG00000174842), score: 0.72 GM2AGM2 ganglioside activator (ENSG00000196743), score: -0.5 GPR1G protein-coupled receptor 1 (ENSG00000183671), score: 0.53 GPR107G protein-coupled receptor 107 (ENSG00000148358), score: -0.53 GRAMD3GRAM domain containing 3 (ENSG00000155324), score: -0.65 GRB10growth factor receptor-bound protein 10 (ENSG00000106070), score: -0.62 GRXCR1glutaredoxin, cysteine rich 1 (ENSG00000215203), score: 0.53 HAPLN1hyaluronan and proteoglycan link protein 1 (ENSG00000145681), score: 0.52 HEATR6HEAT repeat containing 6 (ENSG00000068097), score: 0.76 HELLShelicase, lymphoid-specific (ENSG00000119969), score: 0.58 HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (ENSG00000153187), score: 0.66 HOXB13homeobox B13 (ENSG00000159184), score: 0.87 HPRT1hypoxanthine phosphoribosyltransferase 1 (ENSG00000165704), score: 0.52 HYIhydroxypyruvate isomerase (putative) (ENSG00000178922), score: -0.58 IFNAR1interferon (alpha, beta and omega) receptor 1 (ENSG00000142166), score: -0.56 IFT81intraflagellar transport 81 homolog (Chlamydomonas) (ENSG00000122970), score: 0.64 IKIK cytokine, down-regulator of HLA II (ENSG00000113141), score: -0.54 IKBIPIKBKB interacting protein (ENSG00000166130), score: 0.7 IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (ENSG00000104365), score: -0.73 IL10RBinterleukin 10 receptor, beta (ENSG00000243646), score: -0.57 INPP4Binositol polyphosphate-4-phosphatase, type II, 105kDa (ENSG00000109452), score: 0.57 INVSinversin (ENSG00000119509), score: -0.65 IPPintracisternal A particle-promoted polypeptide (ENSG00000197429), score: 0.92 IRAK1BP1interleukin-1 receptor-associated kinase 1 binding protein 1 (ENSG00000146243), score: 0.53 IWS1IWS1 homolog (S. cerevisiae) (ENSG00000163166), score: 0.51 KBTBD8kelch repeat and BTB (POZ) domain containing 8 (ENSG00000163376), score: 0.62 KDM3Alysine (K)-specific demethylase 3A (ENSG00000115548), score: 0.65 KIAA0146KIAA0146 (ENSG00000164808), score: -0.51 KIAA0174KIAA0174 (ENSG00000182149), score: -0.65 KIAA0895KIAA0895 (ENSG00000164542), score: 0.56 KIAA1609KIAA1609 (ENSG00000140950), score: 0.79 KIAA1712KIAA1712 (ENSG00000164118), score: 0.62 KIF14kinesin family member 14 (ENSG00000118193), score: 0.56 LAMC3laminin, gamma 3 (ENSG00000050555), score: 0.55 LANCL2LanC lantibiotic synthetase component C-like 2 (bacterial) (ENSG00000132434), score: 0.58 LARP4BLa ribonucleoprotein domain family, member 4B (ENSG00000107929), score: -0.58 LCA5Leber congenital amaurosis 5 (ENSG00000135338), score: 0.65 LEMD2LEM domain containing 2 (ENSG00000161904), score: -0.52 LEPRE1leucine proline-enriched proteoglycan (leprecan) 1 (ENSG00000117385), score: 0.51 LIMD2LIM domain containing 2 (ENSG00000136490), score: 0.54 LOC100290337similar to damage-specific DNA binding protein 1 (ENSG00000167986), score: 0.52 LONRF3LON peptidase N-terminal domain and ring finger 3 (ENSG00000175556), score: 0.62 LRATlecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (ENSG00000121207), score: 0.54 LSM10LSM10, U7 small nuclear RNA associated (ENSG00000181817), score: -0.54 LTA4Hleukotriene A4 hydrolase (ENSG00000111144), score: -0.54 MAP3K4mitogen-activated protein kinase kinase kinase 4 (ENSG00000085511), score: -0.51 MAPKAPK3mitogen-activated protein kinase-activated protein kinase 3 (ENSG00000114738), score: -0.51 MED1mediator complex subunit 1 (ENSG00000125686), score: 0.56 MED22mediator complex subunit 22 (ENSG00000148297), score: -0.51 MEMO1mediator of cell motility 1 (ENSG00000162961), score: -0.68 METRNLmeteorin, glial cell differentiation regulator-like (ENSG00000176845), score: -0.55 MID2midline 2 (ENSG00000080561), score: 0.51 MKS1Meckel syndrome, type 1 (ENSG00000011143), score: 0.55 MRPL44mitochondrial ribosomal protein L44 (ENSG00000135900), score: -0.52 MTIF3mitochondrial translational initiation factor 3 (ENSG00000122033), score: -0.72 MTMR3myotubularin related protein 3 (ENSG00000100330), score: 0.57 MYBv-myb myeloblastosis viral oncogene homolog (avian) (ENSG00000118513), score: 0.71 MYL1myosin, light chain 1, alkali; skeletal, fast (ENSG00000168530), score: 0.55 N4BP1NEDD4 binding protein 1 (ENSG00000102921), score: 0.58 NARFnuclear prelamin A recognition factor (ENSG00000141562), score: -0.72 NAT9N-acetyltransferase 9 (GCN5-related, putative) (ENSG00000109065), score: -0.55 ND2MTND2 (ENSG00000198763), score: -0.85 ND4NADH dehydrogenase, subunit 4 (complex I) (ENSG00000198886), score: -0.53 ND6NADH dehydrogenase, subunit 6 (complex I) (ENSG00000198695), score: -0.63 NDUFA8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (ENSG00000119421), score: -0.53 NDUFB9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa (ENSG00000147684), score: -0.5 NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (ENSG00000100906), score: -0.52 NIF3L1NIF3 NGG1 interacting factor 3-like 1 (S. pombe) (ENSG00000196290), score: 0.61 NOXO1NADPH oxidase organizer 1 (ENSG00000196408), score: 0.68 NPSR1neuropeptide S receptor 1 (ENSG00000187258), score: 0.67 NSUN2NOP2/Sun domain family, member 2 (ENSG00000037474), score: -0.65 NTSneurotensin (ENSG00000133636), score: 0.63 NUDCD3NudC domain containing 3 (ENSG00000015676), score: -0.53 NUF2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) (ENSG00000143228), score: 0.52 NUP153nucleoporin 153kDa (ENSG00000124789), score: 0.64 NUP54nucleoporin 54kDa (ENSG00000138750), score: 0.57 NUP85nucleoporin 85kDa (ENSG00000125450), score: 0.51 OSTF1osteoclast stimulating factor 1 (ENSG00000134996), score: -0.53 OTOL1otolin 1 homolog (zebrafish) (ENSG00000182447), score: 0.61 PAPD4PAP associated domain containing 4 (ENSG00000164329), score: 0.67 PARK7Parkinson disease (autosomal recessive, early onset) 7 (ENSG00000116288), score: -0.61 PDE6Gphosphodiesterase 6G, cGMP-specific, rod, gamma (ENSG00000185527), score: 0.62 PFN4profilin family, member 4 (ENSG00000176732), score: 0.51 PGRprogesterone receptor (ENSG00000082175), score: 0.8 PHF12PHD finger protein 12 (ENSG00000109118), score: 0.53 PHF21APHD finger protein 21A (ENSG00000135365), score: 0.53 PHKA2phosphorylase kinase, alpha 2 (liver) (ENSG00000044446), score: 0.55 PHTF1putative homeodomain transcription factor 1 (ENSG00000116793), score: 0.76 PIGLphosphatidylinositol glycan anchor biosynthesis, class L (ENSG00000108474), score: 0.56 PIGSphosphatidylinositol glycan anchor biosynthesis, class S (ENSG00000087111), score: 0.6 PLS3plastin 3 (ENSG00000102024), score: -0.5 PPA2pyrophosphatase (inorganic) 2 (ENSG00000138777), score: -0.7 PPP1R8protein phosphatase 1, regulatory (inhibitor) subunit 8 (ENSG00000117751), score: 0.76 PRCPprolylcarboxypeptidase (angiotensinase C) (ENSG00000137509), score: -0.62 PRKACBprotein kinase, cAMP-dependent, catalytic, beta (ENSG00000142875), score: -0.64 PRKD1protein kinase D1 (ENSG00000184304), score: 0.53 PRSSL1protease, serine-like 1 (ENSG00000185198), score: 0.68 PSMB4proteasome (prosome, macropain) subunit, beta type, 4 (ENSG00000159377), score: -0.54 PUS10pseudouridylate synthase 10 (ENSG00000162927), score: 0.52 PUS3pseudouridylate synthase 3 (ENSG00000110060), score: 0.56 PYCRLpyrroline-5-carboxylate reductase-like (ENSG00000104524), score: 0.81 RAB38RAB38, member RAS oncogene family (ENSG00000123892), score: 0.58 RABEPKRab9 effector protein with kelch motifs (ENSG00000136933), score: -0.65 RGP1RGP1 retrograde golgi transport homolog (S. cerevisiae) (ENSG00000107185), score: 0.77 RIBC2RIB43A domain with coiled-coils 2 (ENSG00000128408), score: 0.5 RIC8Bresistance to inhibitors of cholinesterase 8 homolog B (C. elegans) (ENSG00000111785), score: 0.71 RPE65retinal pigment epithelium-specific protein 65kDa (ENSG00000116745), score: 0.62 RPGRIP1LRPGRIP1-like (ENSG00000103494), score: 0.65 RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 6 (ENSG00000072133), score: 0.56 RPUSD2RNA pseudouridylate synthase domain containing 2 (ENSG00000166133), score: -0.55 SAP30LSAP30-like (ENSG00000164576), score: 0.57 SCML2sex comb on midleg-like 2 (Drosophila) (ENSG00000102098), score: 0.71 SCRN2secernin 2 (ENSG00000141295), score: -0.52 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (ENSG00000197632), score: 0.51 SFRS8splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) (ENSG00000061936), score: 0.54 SGCEsarcoglycan, epsilon (ENSG00000127990), score: 0.54 SGCZsarcoglycan, zeta (ENSG00000185053), score: 0.52 SGOL1shugoshin-like 1 (S. pombe) (ENSG00000129810), score: 0.64 SH3YL1SH3 domain containing, Ysc84-like 1 (S. cerevisiae) (ENSG00000035115), score: -0.51 SIDT1SID1 transmembrane family, member 1 (ENSG00000072858), score: 0.56 SKILSKI-like oncogene (ENSG00000136603), score: 0.55 SLC38A8solute carrier family 38, member 8 (ENSG00000166558), score: 0.76 SLC4A7solute carrier family 4, sodium bicarbonate cotransporter, member 7 (ENSG00000033867), score: 0.69 SMUG1single-strand-selective monofunctional uracil-DNA glycosylase 1 (ENSG00000123415), score: -0.54 SNRKSNF related kinase (ENSG00000163788), score: 0.71 SNX13sorting nexin 13 (ENSG00000071189), score: 0.55 SPG20spastic paraplegia 20 (Troyer syndrome) (ENSG00000133104), score: -0.61 SRPX2sushi-repeat-containing protein, X-linked 2 (ENSG00000102359), score: 0.56 STAU2staufen, RNA binding protein, homolog 2 (Drosophila) (ENSG00000040341), score: -0.51 STILSCL/TAL1 interrupting locus (ENSG00000123473), score: 0.78 STT3BSTT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) (ENSG00000163527), score: 0.52 STX8syntaxin 8 (ENSG00000170310), score: -0.84 TAF4BTAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa (ENSG00000141384), score: 0.51 TDRKHtudor and KH domain containing (ENSG00000182134), score: 0.51 TECTBtectorin beta (ENSG00000119913), score: 0.52 TERTtelomerase reverse transcriptase (ENSG00000164362), score: 0.91 TEX9testis expressed 9 (ENSG00000151575), score: 0.57 THEMISthymocyte selection associated (ENSG00000172673), score: 0.53 THYN1thymocyte nuclear protein 1 (ENSG00000151500), score: -0.75 TM2D2TM2 domain containing 2 (ENSG00000169490), score: -0.5 TMEM100transmembrane protein 100 (ENSG00000166292), score: 0.58 TMEM138transmembrane protein 138 (ENSG00000149483), score: 0.52 TMEM18transmembrane protein 18 (ENSG00000151353), score: -0.62 TMPRSS4transmembrane protease, serine 4 (ENSG00000137648), score: 0.52 TMPRSS7transmembrane protease, serine 7 (ENSG00000176040), score: 0.61 TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (ENSG00000173273), score: 0.58 TOE1target of EGR1, member 1 (nuclear) (ENSG00000132773), score: 0.85 TPMTthiopurine S-methyltransferase (ENSG00000137364), score: -0.65 TRAF3IP1TNF receptor-associated factor 3 interacting protein 1 (ENSG00000204104), score: 0.53 TRIM35tripartite motif-containing 35 (ENSG00000104228), score: -0.71 TRIP12thyroid hormone receptor interactor 12 (ENSG00000153827), score: 0.51 TSNtranslin (ENSG00000211460), score: -0.59 TTLL1tubulin tyrosine ligase-like family, member 1 (ENSG00000100271), score: 0.52 TTLL9tubulin tyrosine ligase-like family, member 9 (ENSG00000131044), score: 0.58 TUFT1tuftelin 1 (ENSG00000143367), score: 0.66 TUSC3tumor suppressor candidate 3 (ENSG00000104723), score: 0.56 UAP1L1UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 (ENSG00000197355), score: -0.53 UBE2G1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) (ENSG00000132388), score: -0.55 UBTD2ubiquitin domain containing 2 (ENSG00000168246), score: 0.51 UNC45Aunc-45 homolog A (C. elegans) (ENSG00000140553), score: -0.51 USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (ENSG00000101557), score: 0.54 USP19ubiquitin specific peptidase 19 (ENSG00000172046), score: 0.57 UTP20UTP20, small subunit (SSU) processome component, homolog (yeast) (ENSG00000120800), score: 0.75 WDR48WD repeat domain 48 (ENSG00000114742), score: 0.76 WDR77WD repeat domain 77 (ENSG00000116455), score: 0.57 ZC3H15zinc finger CCCH-type containing 15 (ENSG00000065548), score: -0.84 ZFYVE1zinc finger, FYVE domain containing 1 (ENSG00000165861), score: 0.51 ZFYVE21zinc finger, FYVE domain containing 21 (ENSG00000100711), score: -0.59 ZMYND10zinc finger, MYND-type containing 10 (ENSG00000004838), score: 0.52 ZMYND19zinc finger, MYND-type containing 19 (ENSG00000165724), score: 0.55 ZNF512zinc finger protein 512 (ENSG00000243943), score: 0.93 ZNF800zinc finger protein 800 (ENSG00000048405), score: 0.62 ZNFX1zinc finger, NFX1-type containing 1 (ENSG00000124201), score: 0.53 ZWILCHZwilch, kinetochore associated, homolog (Drosophila) (ENSG00000174442), score: 0.73

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
mdo_br_f_ca1	mdo	br	f	_
mdo_cb_f_ca1	mdo	cb	f	_
mdo_br_m_ca1	mdo	br	m	_
mdo_cb_m_ca1	mdo	cb	m	_
mdo_ts_m2_ca1	mdo	ts	m	2
mdo_ts_m1_ca1	mdo	ts	m	1