Previous module | Next module Module #594, TG: 1.8, TC: 2.2, 319 probes, 319 Entrez genes, 10 conditions

Help | Hide | Top Expression data


Expression data for module #594

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

hydrogen transport

The directed movement of hydrogen (H2 or H+), into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

proton transport

The directed movement of protons (hydrogen ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

all

NA

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

proton transport

The directed movement of protons (hydrogen ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

proton-transporting two-sector ATPase complex

A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

cell surface

The external part of the cell wall and/or plasma membrane.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

proton-transporting two-sector ATPase complex

A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

exopeptidase activity

Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

monovalent inorganic cation transmembrane transporter activity

Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
05110 6.641e-03 0.8595 6
15 Vibrio cholerae infection
04966 1.626e-02 0.4011 4
7 Collecting duct acid secretion
04960 4.899e-02 0.9168 5
16 Aldosterone-regulated sodium reabsorption

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ENSG00000125257), score: 0.51 ACE2angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ENSG00000130234), score: 0.61 ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 0.63 ACOT11acyl-CoA thioesterase 11 (ENSG00000162390), score: 0.66 ACPPacid phosphatase, prostate (ENSG00000014257), score: 0.91 ACTN4actinin, alpha 4 (ENSG00000130402), score: 0.54 ADMadrenomedullin (ENSG00000148926), score: 0.61 ADPRHL2ADP-ribosylhydrolase like 2 (ENSG00000116863), score: 0.5 AGR2anterior gradient homolog 2 (Xenopus laevis) (ENSG00000106541), score: 0.57 AIM1absent in melanoma 1 (ENSG00000112297), score: 0.59 AKIRIN2akirin 2 (ENSG00000135334), score: -0.45 AKR1A1aldo-keto reductase family 1, member A1 (aldehyde reductase) (ENSG00000117448), score: 0.48 ALPK1alpha-kinase 1 (ENSG00000073331), score: 0.54 ANXA13annexin A13 (ENSG00000104537), score: 0.67 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.54 ARHGAP24Rho GTPase activating protein 24 (ENSG00000138639), score: 0.58 ARMC7armadillo repeat containing 7 (ENSG00000125449), score: 0.61 ARRDC4arrestin domain containing 4 (ENSG00000140450), score: 0.5 ATP10DATPase, class V, type 10D (ENSG00000145246), score: 0.49 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.76 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.73 ATP6V0E1ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 (ENSG00000113732), score: 0.51 ATP6V1C2ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 (ENSG00000143882), score: 0.53 B4GALNT3beta-1,4-N-acetyl-galactosaminyl transferase 3 (ENSG00000139044), score: 0.5 BACE2beta-site APP-cleaving enzyme 2 (ENSG00000182240), score: 0.58 BARX2BARX homeobox 2 (ENSG00000043039), score: 0.77 BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (ENSG00000129151), score: 0.65 BCAP29B-cell receptor-associated protein 29 (ENSG00000075790), score: -0.52 BDKRB2bradykinin receptor B2 (ENSG00000168398), score: 0.75 BNC2basonuclin 2 (ENSG00000173068), score: 0.6 BSPRYB-box and SPRY domain containing (ENSG00000119411), score: 0.51 C18orf1chromosome 18 open reading frame 1 (ENSG00000168675), score: -0.57 C19orf28chromosome 19 open reading frame 28 (ENSG00000161091), score: 0.52 C4orf31chromosome 4 open reading frame 31 (ENSG00000173376), score: 0.53 C8orf84chromosome 8 open reading frame 84 (ENSG00000164764), score: 0.68 C9orf72chromosome 9 open reading frame 72 (ENSG00000147894), score: -0.55 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.85 CALB1calbindin 1, 28kDa (ENSG00000104327), score: 0.48 CAMK1Dcalcium/calmodulin-dependent protein kinase ID (ENSG00000183049), score: -0.45 CAPN13calpain 13 (ENSG00000162949), score: 0.53 CAPN2calpain 2, (m/II) large subunit (ENSG00000162909), score: 0.51 CAPN5calpain 5 (ENSG00000149260), score: 0.5 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.7 CDCP1CUB domain containing protein 1 (ENSG00000163814), score: 0.51 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (ENSG00000113361), score: 0.63 CDK10cyclin-dependent kinase 10 (ENSG00000185324), score: 0.53 CELcarboxyl ester lipase (bile salt-stimulated lipase) (ENSG00000170835), score: 0.57 CHCHD8coiled-coil-helix-coiled-coil-helix domain containing 8 (ENSG00000181924), score: 0.53 CLCN5chloride channel 5 (ENSG00000171365), score: 0.52 CLDN16claudin 16 (ENSG00000113946), score: 0.75 CLDN19claudin 19 (ENSG00000164007), score: 0.49 CLIC5chloride intracellular channel 5 (ENSG00000112782), score: 0.51 CLPTM1LCLPTM1-like (ENSG00000049656), score: 0.55 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.71 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.56 COMTD1catechol-O-methyltransferase domain containing 1 (ENSG00000165644), score: 0.52 CPEB3cytoplasmic polyadenylation element binding protein 3 (ENSG00000107864), score: -0.49 CPMcarboxypeptidase M (ENSG00000135678), score: 0.55 CRTAPcartilage associated protein (ENSG00000170275), score: 0.48 CRYAAcrystallin, alpha A (ENSG00000160202), score: 0.98 CRYL1crystallin, lambda 1 (ENSG00000165475), score: 0.65 CTGFconnective tissue growth factor (ENSG00000118523), score: 0.55 CTNND1catenin (cadherin-associated protein), delta 1 (ENSG00000198561), score: 0.56 CTSHcathepsin H (ENSG00000103811), score: 0.61 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.72 CUX2cut-like homeobox 2 (ENSG00000111249), score: -0.49 CXCL14chemokine (C-X-C motif) ligand 14 (ENSG00000145824), score: 0.65 D2HGDHD-2-hydroxyglutarate dehydrogenase (ENSG00000180902), score: 0.56 DAAM1dishevelled associated activator of morphogenesis 1 (ENSG00000100592), score: -0.56 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.65 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.76 DDHD1DDHD domain containing 1 (ENSG00000100523), score: -0.49 DENND2DDENN/MADD domain containing 2D (ENSG00000162777), score: 0.57 DENND5BDENN/MADD domain containing 5B (ENSG00000170456), score: -0.49 DOK4docking protein 4 (ENSG00000125170), score: 0.53 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.78 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.61 DSG2desmoglein 2 (ENSG00000046604), score: 0.53 EBNA1BP2EBNA1 binding protein 2 (ENSG00000117395), score: 0.57 EGFepidermal growth factor (ENSG00000138798), score: 0.66 EHFets homologous factor (ENSG00000135373), score: 0.59 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.71 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 0.89 ELMO3engulfment and cell motility 3 (ENSG00000102890), score: 0.54 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.63 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.7 ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ENSG00000141736), score: 0.62 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.7 EVCEllis van Creveld syndrome (ENSG00000072840), score: 0.53 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.82 F2RL3coagulation factor II (thrombin) receptor-like 3 (ENSG00000127533), score: 0.53 FAM107Bfamily with sequence similarity 107, member B (ENSG00000065809), score: 0.48 FAM110Cfamily with sequence similarity 110, member C (ENSG00000184731), score: 0.49 FAM150Bfamily with sequence similarity 150, member B (ENSG00000189292), score: 0.67 FAM3Bfamily with sequence similarity 3, member B (ENSG00000183844), score: 0.68 FAM55Cfamily with sequence similarity 55, member C (ENSG00000144815), score: -0.47 FAM60Afamily with sequence similarity 60, member A (ENSG00000139146), score: 0.5 FAM83Bfamily with sequence similarity 83, member B (ENSG00000168143), score: 0.54 FAM83Hfamily with sequence similarity 83, member H (ENSG00000180921), score: 0.55 FARP1FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) (ENSG00000152767), score: 0.59 FBXL5F-box and leucine-rich repeat protein 5 (ENSG00000118564), score: 0.56 FBXO7F-box protein 7 (ENSG00000100225), score: 0.52 FBXW7F-box and WD repeat domain containing 7 (ENSG00000109670), score: -0.5 FEM1Cfem-1 homolog c (C. elegans) (ENSG00000145780), score: -0.45 FGFR4fibroblast growth factor receptor 4 (ENSG00000160867), score: 0.5 FOXI1forkhead box I1 (ENSG00000168269), score: 0.88 FUCA2fucosidase, alpha-L- 2, plasma (ENSG00000001036), score: 0.5 GALNT10UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) (ENSG00000164574), score: 0.56 GALNT11UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (ENSG00000178234), score: 0.52 GALNT14UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (ENSG00000158089), score: 0.57 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.77 GCNT3glucosaminyl (N-acetyl) transferase 3, mucin type (ENSG00000140297), score: 0.67 GHRHRgrowth hormone releasing hormone receptor (ENSG00000106128), score: 0.74 GJA5gap junction protein, alpha 5, 40kDa (ENSG00000143140), score: 0.51 GLB1galactosidase, beta 1 (ENSG00000170266), score: 0.52 GLT1D1glycosyltransferase 1 domain containing 1 (ENSG00000151948), score: -0.45 GPR114G protein-coupled receptor 114 (ENSG00000159618), score: 0.53 GPR160G protein-coupled receptor 160 (ENSG00000173890), score: 0.49 GPR56G protein-coupled receptor 56 (ENSG00000205336), score: 0.6 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.75 HAO2hydroxyacid oxidase 2 (long chain) (ENSG00000116882), score: 0.54 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.58 HNF4Ahepatocyte nuclear factor 4, alpha (ENSG00000101076), score: 0.49 HOXA10homeobox A10 (ENSG00000153807), score: 0.83 HOXB7homeobox B7 (ENSG00000120087), score: 0.73 HOXD10homeobox D10 (ENSG00000128710), score: 0.74 HOXD4homeobox D4 (ENSG00000170166), score: 0.79 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.82 IGFBP7insulin-like growth factor binding protein 7 (ENSG00000163453), score: 0.55 IL1RL1interleukin 1 receptor-like 1 (ENSG00000115602), score: 0.73 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.72 IMPA2inositol(myo)-1(or 4)-monophosphatase 2 (ENSG00000141401), score: 0.76 ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ENSG00000056345), score: 0.75 ITGB6integrin, beta 6 (ENSG00000115221), score: 0.49 ITM2Bintegral membrane protein 2B (ENSG00000136156), score: 0.52 ITPKAinositol 1,4,5-trisphosphate 3-kinase A (ENSG00000137825), score: -0.47 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (ENSG00000006459), score: -0.44 KCNE3potassium voltage-gated channel, Isk-related family, member 3 (ENSG00000175538), score: 0.53 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.87 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.58 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.66 KCNQ1potassium voltage-gated channel, KQT-like subfamily, member 1 (ENSG00000053918), score: 0.6 KIAA0174KIAA0174 (ENSG00000182149), score: 0.49 KIAA0391KIAA0391 (ENSG00000100890), score: 0.49 KIAA1522KIAA1522 (ENSG00000162522), score: 0.49 KIF12kinesin family member 12 (ENSG00000136883), score: 0.67 KIF13Bkinesin family member 13B (ENSG00000197892), score: 0.62 KIRRELkin of IRRE like (Drosophila) (ENSG00000183853), score: 0.56 KLklotho (ENSG00000133116), score: 0.71 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.69 KLHL28kelch-like 28 (Drosophila) (ENSG00000179454), score: -0.48 LAD1ladinin 1 (ENSG00000159166), score: 0.59 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.8 LIFleukemia inhibitory factor (cholinergic differentiation factor) (ENSG00000128342), score: 0.61 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.62 LMBRD2LMBR1 domain containing 2 (ENSG00000164187), score: -0.45 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.89 LOC100294412similar to KIAA0655 protein (ENSG00000130787), score: 0.49 LPIN3lipin 3 (ENSG00000132793), score: 0.58 MALmal, T-cell differentiation protein (ENSG00000172005), score: 0.59 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.52 METRNLmeteorin, glial cell differentiation regulator-like (ENSG00000176845), score: 0.54 METTL9methyltransferase like 9 (ENSG00000197006), score: 0.64 MMDmonocyte to macrophage differentiation-associated (ENSG00000108960), score: -0.47 MMP7matrix metallopeptidase 7 (matrilysin, uterine) (ENSG00000137673), score: 1 MPP5membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (ENSG00000072415), score: 0.54 MSNmoesin (ENSG00000147065), score: 0.49 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.51 MYO19myosin XIX (ENSG00000141140), score: 0.48 MYO6myosin VI (ENSG00000196586), score: 0.58 NDRG4NDRG family member 4 (ENSG00000103034), score: -0.48 NINJ1ninjurin 1 (ENSG00000131669), score: 0.49 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.79 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.96 NPNTnephronectin (ENSG00000168743), score: 0.68 NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (ENSG00000113389), score: 0.66 NTN4netrin 4 (ENSG00000074527), score: 0.51 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.57 OGG18-oxoguanine DNA glycosylase (ENSG00000114026), score: 0.5 OLFM4olfactomedin 4 (ENSG00000102837), score: 0.74 ORC6Lorigin recognition complex, subunit 6 like (yeast) (ENSG00000091651), score: -0.51 OVCH2ovochymase 2 (gene/pseudogene) (ENSG00000183378), score: 0.81 PABPC1Lpoly(A) binding protein, cytoplasmic 1-like (ENSG00000101104), score: 0.51 PAPPApregnancy-associated plasma protein A, pappalysin 1 (ENSG00000182752), score: 0.68 PAPPA2pappalysin 2 (ENSG00000116183), score: 0.8 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.58 PAQR9progestin and adipoQ receptor family member IX (ENSG00000188582), score: -0.49 PCGF2polycomb group ring finger 2 (ENSG00000056661), score: 0.49 PELI1pellino homolog 1 (Drosophila) (ENSG00000197329), score: -0.44 PEPDpeptidase D (ENSG00000124299), score: 0.73 PGAP3post-GPI attachment to proteins 3 (ENSG00000161395), score: 0.51 PGPEP1pyroglutamyl-peptidase I (ENSG00000130517), score: 0.52 PHLPP1PH domain and leucine rich repeat protein phosphatase 1 (ENSG00000081913), score: -0.51 PICALMphosphatidylinositol binding clathrin assembly protein (ENSG00000073921), score: 0.5 PLA2R1phospholipase A2 receptor 1, 180kDa (ENSG00000153246), score: 0.8 PLATplasminogen activator, tissue (ENSG00000104368), score: 0.59 PLAUplasminogen activator, urokinase (ENSG00000122861), score: 0.6 PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific) (ENSG00000197943), score: 0.82 PLEK2pleckstrin 2 (ENSG00000100558), score: 0.67 PLEKHJ1pleckstrin homology domain containing, family J member 1 (ENSG00000104886), score: 0.6 PNPLA1patatin-like phospholipase domain containing 1 (ENSG00000180316), score: 0.77 PPCSphosphopantothenoylcysteine synthetase (ENSG00000127125), score: 0.5 PPP4R4protein phosphatase 4, regulatory subunit 4 (ENSG00000119698), score: -0.45 PRCPprolylcarboxypeptidase (angiotensinase C) (ENSG00000137509), score: 0.49 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (ENSG00000111725), score: 0.71 PROM2prominin 2 (ENSG00000155066), score: 0.84 PROX1prospero homeobox 1 (ENSG00000117707), score: -0.55 PRSS23protease, serine, 23 (ENSG00000150687), score: 0.55 PSKH1protein serine kinase H1 (ENSG00000159792), score: 0.49 PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (ENSG00000197170), score: -0.48 PTGER4prostaglandin E receptor 4 (subtype EP4) (ENSG00000171522), score: 0.48 PTPN1protein tyrosine phosphatase, non-receptor type 1 (ENSG00000196396), score: 0.56 PTPRQprotein tyrosine phosphatase, receptor type, Q (ENSG00000139304), score: 0.5 QARSglutaminyl-tRNA synthetase (ENSG00000172053), score: 0.55 R3HDM1R3H domain containing 1 (ENSG00000048991), score: -0.45 RAB11FIP1RAB11 family interacting protein 1 (class I) (ENSG00000156675), score: 0.54 RAB11FIP3RAB11 family interacting protein 3 (class II) (ENSG00000090565), score: 0.58 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.66 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.48 RAB38RAB38, member RAS oncogene family (ENSG00000123892), score: 0.54 RAB7L1RAB7, member RAS oncogene family-like 1 (ENSG00000117280), score: 0.65 RAMP3receptor (G protein-coupled) activity modifying protein 3 (ENSG00000122679), score: 0.51 RASL11ARAS-like, family 11, member A (ENSG00000122035), score: 0.5 RBKSribokinase (ENSG00000171174), score: 0.48 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.81 RIPK4receptor-interacting serine-threonine kinase 4 (ENSG00000183421), score: 0.59 RLFrearranged L-myc fusion (ENSG00000117000), score: -0.48 RNF152ring finger protein 152 (ENSG00000176641), score: 0.7 RPS6KA1ribosomal protein S6 kinase, 90kDa, polypeptide 1 (ENSG00000117676), score: 0.51 SACSspastic ataxia of Charlevoix-Saguenay (sacsin) (ENSG00000151835), score: -0.45 SAP30Sin3A-associated protein, 30kDa (ENSG00000164105), score: -0.52 SCINscinderin (ENSG00000006747), score: 0.7 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.78 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.73 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.74 SCRN2secernin 2 (ENSG00000141295), score: 0.58 SDC4syndecan 4 (ENSG00000124145), score: 0.51 SEH1LSEH1-like (S. cerevisiae) (ENSG00000085415), score: -0.47 SGK196protein kinase-like protein SgK196 (ENSG00000185900), score: -0.52 SGK2serum/glucocorticoid regulated kinase 2 (ENSG00000101049), score: 0.55 SH3YL1SH3 domain containing, Ysc84-like 1 (S. cerevisiae) (ENSG00000035115), score: 0.68 SHFSrc homology 2 domain containing F (ENSG00000138606), score: -0.47 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.6 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.79 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.49 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.72 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.67 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (ENSG00000088386), score: 0.56 SLC16A12solute carrier family 16, member 12 (monocarboxylic acid transporter 12) (ENSG00000152779), score: 0.54 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.72 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (ENSG00000162383), score: 0.53 SLC22A7solute carrier family 22 (organic anion transporter), member 7 (ENSG00000137204), score: 0.5 SLC25A10solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 (ENSG00000183048), score: 0.52 SLC25A42solute carrier family 25, member 42 (ENSG00000181035), score: 0.5 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.86 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.73 SLC35F2solute carrier family 35, member F2 (ENSG00000110660), score: 0.55 SLC39A13solute carrier family 39 (zinc transporter), member 13 (ENSG00000165915), score: 0.5 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.65 SLC44A3solute carrier family 44, member 3 (ENSG00000143036), score: 0.7 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.81 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.56 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.74 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.73 SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 3 (ENSG00000066230), score: 0.69 SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (ENSG00000109062), score: 0.51 SLC9A4solute carrier family 9 (sodium/hydrogen exchanger), member 4 (ENSG00000180251), score: 0.8 SLIT2slit homolog 2 (Drosophila) (ENSG00000145147), score: 0.49 SMOsmoothened homolog (Drosophila) (ENSG00000128602), score: 0.55 SNX29sorting nexin 29 (ENSG00000048471), score: 0.54 SNX5sorting nexin 5 (ENSG00000089006), score: 0.65 SOSTDC1sclerostin domain containing 1 (ENSG00000171243), score: 0.57 SOX13SRY (sex determining region Y)-box 13 (ENSG00000143842), score: 0.5 SPASTspastin (ENSG00000021574), score: -0.5 SPP1secreted phosphoprotein 1 (ENSG00000118785), score: 0.61 SPTLC3serine palmitoyltransferase, long chain base subunit 3 (ENSG00000172296), score: 0.73 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.63 STAP1signal transducing adaptor family member 1 (ENSG00000035720), score: 0.49 STC1stanniocalcin 1 (ENSG00000159167), score: 0.53 STK24serine/threonine kinase 24 (ENSG00000102572), score: 0.48 STK32Bserine/threonine kinase 32B (ENSG00000152953), score: 0.8 SULF2sulfatase 2 (ENSG00000196562), score: 0.54 SUMF1sulfatase modifying factor 1 (ENSG00000144455), score: 0.6 SUSD1sushi domain containing 1 (ENSG00000106868), score: 0.61 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.62 SUSD3sushi domain containing 3 (ENSG00000157303), score: 0.52 TAOK1TAO kinase 1 (ENSG00000160551), score: -0.44 TBC1D1TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (ENSG00000065882), score: 0.66 TBC1D13TBC1 domain family, member 13 (ENSG00000107021), score: 0.57 TBX2T-box 2 (ENSG00000121068), score: 0.72 TCF21transcription factor 21 (ENSG00000118526), score: 0.58 TCN2transcobalamin II (ENSG00000185339), score: 0.53 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.85 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.76 TM7SF3transmembrane 7 superfamily member 3 (ENSG00000064115), score: 0.63 TMCO4transmembrane and coiled-coil domains 4 (ENSG00000162542), score: 0.48 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.59 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.65 TMEM51transmembrane protein 51 (ENSG00000171729), score: 0.61 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.76 TMPRSS4transmembrane protease, serine 4 (ENSG00000137648), score: 0.82 TNFSF15tumor necrosis factor (ligand) superfamily, member 15 (ENSG00000181634), score: 0.57 TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (ENSG00000173273), score: -0.47 TNRC6Ctrinucleotide repeat containing 6C (ENSG00000078687), score: -0.6 TOM1L1target of myb1 (chicken)-like 1 (ENSG00000141198), score: 0.52 TRIM23tripartite motif-containing 23 (ENSG00000113595), score: -0.44 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.77 VCAM1vascular cell adhesion molecule 1 (ENSG00000162692), score: 0.71 WDR1WD repeat domain 1 (ENSG00000071127), score: 0.5 WDR34WD repeat domain 34 (ENSG00000119333), score: 0.48 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.82 WISP1WNT1 inducible signaling pathway protein 1 (ENSG00000104415), score: 0.53 WNT8Bwingless-type MMTV integration site family, member 8B (ENSG00000075290), score: 0.56 XPCxeroderma pigmentosum, complementation group C (ENSG00000154767), score: 0.49 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.73 ZDHHC6zinc finger, DHHC-type containing 6 (ENSG00000023041), score: 0.53 ZFATzinc finger and AT hook domain containing (ENSG00000066827), score: 0.52 ZFPM2zinc finger protein, multitype 2 (ENSG00000169946), score: -0.44 ZNF618zinc finger protein 618 (ENSG00000157657), score: 0.59

Non-Entrez genes

Unknown, score:

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Id species tissue sex individual
mml_kd_f_ca1 mml kd f _
ptr_kd_f_ca1 ptr kd f _
ppa_kd_m_ca1 ppa kd m _
ggo_kd_m_ca1 ggo kd m _
ggo_kd_f_ca1 ggo kd f _
ptr_kd_m_ca1 ptr kd m _
ppa_kd_f_ca1 ppa kd f _
hsa_kd_f_ca1 hsa kd f _
hsa_kd_m2_ca1 hsa kd m 2
hsa_kd_m1_ca1 hsa kd m 1

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