Difference between revisions of "Daniel Marbach"
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* 2009 - 2013: Postdoctoral Fellow at [http://compbio.mit.edu Manolis Kellis' group], '''Broad Institute of MIT and Harvard''' | * 2009 - 2013: Postdoctoral Fellow at [http://compbio.mit.edu Manolis Kellis' group], '''Broad Institute of MIT and Harvard''' | ||
* 2005 - 2009: PhD Student at [http://lis.epfl.ch Dario Floreano's group], '''EPFL''' | * 2005 - 2009: PhD Student at [http://lis.epfl.ch Dario Floreano's group], '''EPFL''' | ||
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== Research == | == Research == | ||
Revision as of 16:25, 4 April 2016
File:Daniel Marbach.png
Daniel Marbach
Short bio
- Since 2013: Senior Researcher at Sven Bergmann's group, University of Lausanne
- 2009 - 2013: Postdoctoral Fellow at Manolis Kellis' group, Broad Institute of MIT and Harvard
- 2005 - 2009: PhD Student at Dario Floreano's group, EPFL
Research
The overarching aim of my work is to:
- (1) Develop computational methods to unravel molecular networks from large-scale data
- (2) Leverage these networks to improve our understanding of genetic variants and disease mechanisms
I have a strong interest in open, collaborative approaches to tackle these problems. As part of the DREAM Challenges, I develop and lead crowdsourced competitions addressing key challenges in systems biology and translational medicine. By bringing together teams of researchers working on the same problem, I leverage the wisdom of crowds to accelerate biological and biomedical discoveries.
Publications
Selected publications:
- Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases. (PDF)
Marbach D, Lamparter D, Quon G, Kellis M, Kutalik Z, and Bergmann S.
Nature Methods, 13, 366-370, 2016. - Fast and rigorous computation of gene and pathway scores from SNP-based summary statistics. (PDF)
Lamparter D*, Marbach D*, Rueedi R, Kutalik Z, and Bergmann S.
PLoS Computational Biology 12, e1004714, 2016. - Wisdom of crowds for robust gene network inference. (PDF)
Marbach D*, Costello JC*, Küffner R*, Vega NM, Prill RJ, Camacho DM, Allison KR, The DREAM5 Consortium, Kellis M, Collins JJ, Stolovitzky G.
Nature Methods, 9, 796-804, 2012. - Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks. (PDF)
Marbach D*, Roy S*, Ay F, Meyer PE, Candeias R, Kahveci T, Bristow CA, Kellis M.
Genome Research, 22, 1334-49, 2012. - Revealing strengths and weaknesses of methods for gene network inference. (PDF)
Marbach D, Prill RJ, Schaffter T, Mattiussi C, Floreano D, Stolovitzky G.
PNAS, 107, 6286-6291, 2010.
Complete list of publications: Google Scholar
Web sites
Contact
- Address: Rue du Bugnon 27 - DGM 023 - CH-1005 Lausanne - Switzerland
- Phone at work: +41-21-692-5378
- Cell phone: +41-78-966-3168
- e-mail: daniel.marb...@unil.ch (fill in the blank)
