Control of mitosis in fission yeast
Background: Fission yeast cells growth up to a given size and then enters mitosis. The question this project addresses is how does the cell knows it has reached to right size for division. This is achieved by a gradient of the pom1 protein along the cortex.
Goal: The goal is to mathematically describe the mechanism by which such a gradient is achieved using differential equation and analyze such gradients from fluorescence microscopy images.
Mathematical tools: Ordinary differential equations, Mathematica, Matlab, ImageJ
Biological or Medical aspects: Size regulation in the fission yeast
Supervisor: Sascha Dalessi
Students: Degrugillier Lucas, Delapierre Fabien, Merçay Johan.
Presentation:
References: <biblio>
- hachet10 pmid=21703453
</biblio> <a href="http://cshperspectives.cshlp.org/content/1/3/a001255.full.pdf+html">Morpho </a>
Back to UNIL BSc course: "Solving Biological Problems that require Math 2012"]
