Bias in de novo germline mutation rates

Background: A crucial aspect of evolution and a key component of its creativity is the

Goal: The goal of this project is to identify the presence of biases affecting de novo germline mutations. In other words, the students will try to identify what are the factors influencing the probability of spontaneous mutations. We will focus on single nucleotide mutations.

Mathematical tools: Statistics, linear regression, mixed models

Biological aspects: The biology of germline mutations and their consequence in terms of population genetics.

Supervisor: [ User:Micha | Micha]