# Modeling gradient formation in the fission yeast

**Background** Molecular gradients are widely used in biological systems to convey positional information. In fission yeast the Pom1 gradient is used to determine the positioning and timing of the cell division.

**Aim**: The aim is to mathematically model the Pom1 gradient formation, compute the precision that can be expected from such a gradient and compare it to the precision that can be actually observed in fission yeast cells

**Mathematical Tools** Partial differential equations, statistics. The R software will be used

**Biological aspects** The students will learn aspects of cell cycle control in fission yeast and get acquainted with the notion of robustness in biological systems

**Supervisor** Micha

For further information see the project page: [http://www2.unil.ch/cbg/index.php?title=ProjectYeast ]