Difference between revisions of "Narcolepsy"
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We are involved in a [[Genome Wide Association Studies | Genome-wide Association Study]] on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics]. | We are involved in a [[Genome Wide Association Studies | Genome-wide Association Study]] on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics]. | ||
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| + | 20671149 | ||
| + | </pubmed> | ||
Revision as of 16:04, 20 April 2011
We are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti's Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in Nature Genetics.
Lüscher A, Csárdi G, de Lachapelle AM, Kutalik Z, Peter B, Bergmann S
ExpressionView--an interactive viewer for modules identified in gene expression data.
Bioinformatics: 2010 Aug 15, 26(16);2062-3
[PubMed:20671149]
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