Difference between revisions of "Narcolepsy"
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| − | <newstitle>Genome-wide Association Study reveals | + | <newstitle>Genome-wide Association Study reveals new HLA-haplotype strongly protective against narcolepsy</newstitle> |
<teaser> | <teaser> | ||
| − | + | In collaboration with Mehdi Tafti's research group we have published our recent discovery on a newly identified HLA haplotype that protects individuals from narcolepsy even if they carry the famous risk haplotype. Our article appeared online in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics] on 15 August 2010. | |
<date>16 Aug 2010 — 11:45</date> | <date>16 Aug 2010 — 11:45</date> | ||
</teaser> | </teaser> | ||
We are involved in a Genome-wide Association Study on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics]. | We are involved in a Genome-wide Association Study on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics]. | ||
Revision as of 10:55, 16 August 2010
We are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti's Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in Nature Genetics.
