Narcolepsy

We are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti's Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in Nature Genetics.

Lüscher A, Csárdi G, de Lachapelle AM, Kutalik Z, Peter B, Bergmann S
ExpressionView--an interactive viewer for modules identified in gene expression data.
Bioinformatics: 2010 Aug 15, 26(16);2062-3
[PubMed:20671149] [WorldCat.org: ISSN ESSN ] [DOI] ( o)