Slightly off topic relative to the usual journal-club posts, but I think that this is relevant to understanding where we are going with genomics for studying variability:
Next-Gen 101: Video Tutorial on Conducting Whole-Exome Sequencing Research from the National Human Genome Research Institute
(from the Nielsen lab blog)
Cool, thanks Marc!If interested in exome sequencing, here is another discussion thread :The-Beginning-of-the-End-for-Exome-Sequencingalso commented in NGS Linkedin discussion group:death-exome-sequencing